Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Niculin J Herz"'
Autor:
Nunzia Pastore, Anna Vainshtein, Tiemo J Klisch, Andrea Armani, Tuong Huynh, Niculin J Herz, Elena V Polishchuk, Marco Sandri, Andrea Ballabio
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 5, Pp 605-621 (2017)
Abstract TFE3 and TFEB are members of the MiT family of HLH–leucine zipper transcription factors. Recent studies demonstrated that they bind overlapping sets of promoters and are post‐transcriptionally regulated through a similar mechanism. Howev
Externí odkaz:
https://doaj.org/article/3577a82b5d6945a083275779521971e1
Autor:
Nunzia Pastore, Tuong Huynh, Niculin J. Herz, Alessia Calcagni’, Tiemo J. Klisch, Lorenzo Brunetti, Kangho Ho Kim, Marco De Giorgi, Ayrea Hurley, Annamaria Carissimo, Margherita Mutarelli, Niya Aleksieva, Luca D’Orsi, William R. Lagor, David D. Moore, Carmine Settembre, Milton J. Finegold, Stuart J. Forbes, Andrea Ballabio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The Transcription Factor EB (TFEB) is known to regulate cellular homeostasis and energy metabolism, but its role in cell fate determination in the liver is unknown. Here, the authors show that TFEB regulates the progenitor/cholangiocyte lineage and t
Externí odkaz:
https://doaj.org/article/dac8c6aa736f4598a4966ab084bf32fc
Autor:
Tuong Huynh, Alessia Calcagni, Ayrea Hurley, Milton J. Finegold, Stuart J. Forbes, Nunzia Pastore, William R. Lagor, Luca D’Orsi, Carmine Settembre, Niculin J. Herz, Marco De Giorgi, Tiemo J. Klisch, Lorenzo Brunetti, David D. Moore, Margherita Mutarelli, Andrea Ballabio, Niya Aleksieva, Annamaria Carissimo, Kangho Ho Kim
Publikováno v:
Pastore, N, Huynh, T, Herz, N J, Calcagni, A, Klisch, T J, Brunetti, L, Kim, K H, De Giorgi, M, Hurley, A, Carissimo, A, Mutarelli, M, Aleksieva, N, D'Orsi, L, Lagor, W R, Moore, D D, Settembre, C, Finegold, M J, Forbes, S & Ballabio, A 2020, ' TFEB regulates murine liver cell fate during development and regeneration ', Nature Communications, vol. 11, no. 1, 2461 . https://doi.org/10.1038/s41467-020-16300-x
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications
It is well established that pluripotent stem cells in fetal and postnatal liver (LPCs) can differentiate into both hepatocytes and cholangiocytes. However, the signaling pathways implicated in the differentiation of LPCs are still incompletely unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5314b8c610c8b861361f1fbdf8cd1a
https://hdl.handle.net/20.500.11820/28ac7cb3-4fea-443e-8589-7951236bbe85
https://hdl.handle.net/20.500.11820/28ac7cb3-4fea-443e-8589-7951236bbe85
Autor:
Kenichiro Kinouchi, Anna Vainshtein, Patrizia Annunziata, Tuong Huynh, Nicola Brunetti-Pierri, Paolo Sassone-Corsi, Lorenzo Brunetti, Andrea Ballabio, Tiemo J. Klisch, Niculin J. Herz, Nunzia Pastore, Margherita Mutarelli
Publikováno v:
EMBO J
The EMBO journal, vol 38, iss 12
The EMBO journal, vol 38, iss 12
Autophagy and energy metabolism are known to follow a circadian pattern. However, it is unclear whether autophagy and the circadian clock are coordinated by common control mechanisms. Here, we show that the oscillation of autophagy genes is dependent
Autor:
Tuong Huynh, Tiemo J. Klisch, Niculin J. Herz, Anna Vainshtein, Elena V. Polishchuk, Andrea Armani, Nunzia Pastore, Andrea Ballabio, Marco Sandri
Publikováno v:
EMBO Molecular Medicine
TFE3 and TFEB are members of the MiT family of HLH–leucine zipper transcription factors. Recent studies demonstrated that they bind overlapping sets of promoters and are post‐transcriptionally regulated through a similar mechanism. However, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09839133d7862f5d966c50d8429c7bdb
http://hdl.handle.net/11588/667379
http://hdl.handle.net/11588/667379
Autor:
Niculin J. Herz, Sofie Bergstrand, Anna Tamburrino, Rossana Ippolito, Mickael Decressac, Oi Wan Wan, Daniel Wolf, Charles K. Meshul, Anders Björklund, Madeline J Churchill, Michelle D Sconce, Yolanda Colino-Sanguino
Publikováno v:
Acta Neuropathologica Communications
Background The early clinical trials using fetal ventral mesencephalic (VM) allografts in Parkinson’s disease (PD) patients have shown efficacy (albeit not in all cases) and have paved the way for further development of cell replacement therapy str
Autor:
Alessia Calcagni’, Leopoldo Staiano, Nicolina Zampelli, Nadia Minopoli, Niculin J. Herz, Giuseppe Di Tullio, Tuong Huynh, Jlenia Monfregola, Alessandra Esposito, Carmine Cirillo, Aleksandar Bajic, Mahla Zahabiyon, Rachel Curnock, Elena Polishchuk, Luke Parkitny, Diego Luis Medina, Nunzia Pastore, Peter J. Cullen, Giancarlo Parenti, Maria Antonietta De Matteis, Paolo Grumati, Andrea Ballabio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Batten disease, one of the most devastating types of neurodegenerative lysosomal storage disorders, is caused by mutations in CLN3. Here, we show that CLN3 is a vesicular trafficking hub connecting the Golgi and lysosome compartments. Proteo
Externí odkaz:
https://doaj.org/article/6b4c5ef6c8024f6aa64e8fc752ca2920