Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Nicos, Angelopoulos"'
Autor:
Andrew Muir, Basudev Paudyal, Selma Schmidt, Ehsan Sedaghat-Rostami, Soumendu Chakravarti, Sonia Villanueva-Hernández, Katy Moffat, Noemi Polo, Nicos Angelopoulos, Anna Schmidt, Matthias Tenbusch, Graham Freimanis, Wilhelm Gerner, Arianne C Richard, Elma Tchilian
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1011910 (2024)
The pig is a natural host for influenza viruses and integrally involved in virus evolution through interspecies transmissions between humans and swine. Swine have many physiological, anatomical, and immunological similarities to humans, and are an ex
Externí odkaz:
https://doaj.org/article/bc240ee05da74cccb8d07006bf4911f8
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Bayesian network inference on several blood and solid cancer genomic datasets provides more accessible ways to explore driver events in cancer.
Externí odkaz:
https://doaj.org/article/9cd6211b053c4064aaf9b1e2c3b20d65
Autor:
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment. Identifying biomarkers that can reliably diagnose
Externí odkaz:
https://doaj.org/article/372307b61d504c2f82b75430deb7c6d3
Autor:
Even H. Rustad, Ferran Nadeu, Nicos Angelopoulos, Bachisio Ziccheddu, Niccolò Bolli, Xose S. Puente, Elias Campo, Ola Landgren, Francesco Maura
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Rustad et al. present a software package for the R statistical environment for the accurately quantify of somatic mutational signatures in hematological malignancies
Externí odkaz:
https://doaj.org/article/1798eaafba7b4603af2c13853c09ffc6
Autor:
Even H. Rustad, Venkata Yellapantula, Daniel Leongamornlert, Niccolò Bolli, Guy Ledergor, Ferran Nadeu, Nicos Angelopoulos, Kevin J. Dawson, Thomas J. Mitchell, Robert J. Osborne, Bachisio Ziccheddu, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, Philippe Moreau, Elli Papaemmanuil, Ludmil B. Alexandrov, Xose S. Puente, Elias Campo, Reiner Siebert, Herve Avet-Loiseau, Ola Landgren, Nikhil Munshi, Peter J. Campbell, Francesco Maura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The initial mutational processes and how these lead to progression in multiple myeloma (MM) are unclear. Here, the authors identify mutational signatures that occur over time in a large cohort of MM patients and suggest features that may help in earl
Externí odkaz:
https://doaj.org/article/5bcecbd98cdc4f9fbf76239987880049
Autor:
Nicos Angelopoulos, Jan Wielemaker
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 306, Iss Proc. ICLP 2019, Pp 309-322 (2019)
Delivering effective data analytics is of crucial importance to the interpretation of the multitude of biological datasets currently generated by an ever increasing number of high throughput techniques. Logic programming has much to offer in this are
Externí odkaz:
https://doaj.org/article/c65cbe3fb8514ab6980138d1d49cf104
Autor:
Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C. Anderson, Jose M. C. Tubio, David C. Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J. Campbell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.
Externí odkaz:
https://doaj.org/article/a38608a486ef471e8da57b4ab94d19b3
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 740-746 (2016)
Tyrosine kinases (TKs) play an essential role in regulating various cellular activities and dysregulation of TK signaling contributes to oncogenesis. However, less than half of the TKs have been thoroughly studied. Through a combined use of RNAi and
Externí odkaz:
https://doaj.org/article/0975c39c76d14b21aac2eabaf1342f16
Autor:
Yichen Xu, Hua Zhang, Van Thuy Mai Nguyen, Nicos Angelopoulos, Joao Nunes, Alistair Reid, Laki Buluwela, Luca Magnani, Justin Stebbing, Georgios Giamas
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 837-849 (2015)
LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer, including breast, lung, gastric, and colorectal cancer. It is localized in different cellular compartments, but its nuclear function has not been investigated
Externí odkaz:
https://doaj.org/article/4f5d33af40df4d308e7e51b76320a8af
Autor:
Niccolo Bolli, Xose S. Puente, Ferran Nadeu, Elias Campo, Francesco Maura, Bachisio Ziccheddu, Nicos Angelopoulos, Even H Rustad, Ola Landgren
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Communications Biology
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Mutational signatures have emerged as powerful biomarkers in cancer patients, with prognostic and therapeutic implications. Wider clinical utility requires access to reproducible algorithms, which allow characterization of mutational signatures in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434d3aed20df22bce033cbc717b1e35d
https://doaj.org/article/1798eaafba7b4603af2c13853c09ffc6
https://doaj.org/article/1798eaafba7b4603af2c13853c09ffc6