Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice

Autor: Smith, Christopher W., Campos, Joana, Brown, Helena C., Jooss, Natalie J., Ivanova, Vanesa-Sindi, Harbi, Maan, Garcia-Quintanilla, Lourdes, Jossi, Sian, Perez-Toledo, Marisol, Rookes, Kieran, Brill, Alexander, Theodore, Lindsay N., Owens, Tim, LaStant, Jacob, Foulke, Matthew C., Mukai, Shin, Francesco, Michelle, Storek, Michael, Hicks, Alexandra, Langrish, Claire, Nunn, Philip A., Cunningham, Adam F., Chauhan, Abhi, Thomas, Mark R., Watson, Steve P., Nicolson, Phillip L. R.

Publikováno v: In Blood Advances 12 November 2024 8(21):5557-5570

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The Btk inhibitor AB‐95‐LH34 potently inhibits atherosclerotic plaque–induced thrombus formation and platelet procoagulant activity

Autor: Smith, Christopher W., Harbi, Maan H., Garcia‐Quintanilla, Lourdes, Rookes, Kieran, Brown, Helena, Poulter, Natalie S., Watson, Steve P., Nicolson, Phillip L.R. ^*, Thomas, Mark R.

Publikováno v: In Journal of Thrombosis and Haemostasis December 2022 20(12):2939-2952

Diagnostic uncertainty presented barriers to the timely management of acute thrombotic thrombocytopenic purpura in the United Kingdom between 2014 and 2019

Autor: Bull, Tom P., McCulloch, Rory, Nicolson, Phillip L.R., Doyle, Andrew J., Shaw, Rebecca J., Langridge, Alexander, Sayar, Zara, Tucker, David L., Pettit, Michala, Perry, Rita, Thomas, William, Page, Catherine, Whalley, Ioana, Dutt, Tina, Garth, Louise, Lester, Will, Buka, Richard J., Subhan, Mary, Ware, Victoria, Rayment, Rachel, Castle, Daniel, Etherington, Astrid, Carter‐Brzezinski, Luke, Peters, Jayne, Corrigan, Claire, Sharma, Narind, Benson, Gary, Challenor, Sarah, Skinner, Thomas S., Zhao, Rui, McLeod‐Kennedy, Lyndsay A.G., Douglas, Kenneth, Knott, Amy, Smith, Sophie, Wolf, Julia, Todd, Sophie A., McDonald, Vickie, Rampotas, Alexandros, Dean, Christopher, Sangha, Gavinda, Pavord, Sue, Denny, Nicholas, Jaafar, Sarah, McLaughlin, David P.T., Ross, Jennifer E., Karanth, Mamatha, Beverstock, Sarah L., Mansonso, Lynn, Burrows, Samuel H., Tauro, Sudhir, Shenouda, Amir, Bailiff, Benjamin M., Kajita, Daniel, Hermans, Joannes, Goradia, Harshita, Finan, Emily M., Alford, Sarah, Pickard, Keir, Greystoke, Brigit, Fail, Thomas, Abdussalam, Asmaa, Roberts, Lara N, Clark, James B., Heeney, Natalie, Young, Jennifer, Maddox, Jamie, Srinath, Swathy, Khawaja, Jahanzeb, Parkes, Jayne, Babiker, Samah, Hunt, Beverley J., Wheeldon, Sarah L., Kerr, Paul, Tahhan, Molham, Vickers, Mark, Pike, Alexandra C., Hill, Quentin, Mustafa, Nadreen, Almaremi, Azza, Hughes, Emily, McGoldrick, Sean J.F., Loizou, Eleana, James, Izabela, Boyce, Sara R., Farmer, Isabel, Thanigaikumar, Murugaiyan, Wickenden, Katherine, Gooding, Richard, Thornton, Kathryn, Kane, Clare, Cole, Adam, Griffin, JessicaC, Docherty, Suzanne, Dixon, Kiri I., Crowe, Josephine, Sheridan, Mathew, De Lord, Corinne, Sud, Amit, Austin, Anna, Coooper, Nichola, Bailey, Chris, Attwell, Luke, Hall, Rachel, Gray, Benjamin, Chauhan, Salena R., Lokare, Anand, Gudger, Amy, Horgan, Claire, Venkatadasari, Indrani, Kaddam, Israa, Mapplebeck, Claire L., Van Veen, Joost, Raj, Maya, De Abrew, Kanchana, Belsham, Edward, Gyansah, Cecilia, Sadullah, Shalal, Salhan, Beena, Murrin, Richard, Williams, Rhys L., Stewart, Andrew, Cornish, Naomi, Otton, Sophie, Khan, Zeeshan, Ackroyd, Sam, Chen, Lucia Y., Lafferty, Nicholas P., Leonforte, Francesca, Pemberton, Nicholas, Rawi, Emanal, Triantafyllopoulou, Diana, Adiyodi, Jagdish, Yong, Jun, Jones, Elizabeth, Davies, David, Peck, Rachel C., Philip, Robson, Seddon, Thomas, Cahalin, Paul, Prodger, Catherine, Dutton, David A., Sternberg, Alexander J., Chengal, Rajani, Polzella, Paolo, Scully, Marie

Publikováno v: In Journal of Thrombosis and Haemostasis June 2022 20(6):1428-1436

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