Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Nicolle Kränkel"'
Autor:
Katharina Lechner, Sylvia Kia, Pia von Korn, Sophia M. Dinges, Stephan Mueller, Arnt-Erik Tjønna, Ulrik Wisløff, Emeline M. Van Craenenbroeck, Burkert Pieske, Volker Adams, Axel Pressler, Ulf Landmesser, Martin Halle, Nicolle Kränkel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundMetabolic syndrome (MetS) is defined by the presence of central obesity plus ≥two metabolic/cardiovascular risk factors (RF), with inflammation being a major disease-driving mechanism. Structured endurance exercise training (ET) may posit
Externí odkaz:
https://doaj.org/article/c38112165f794ac9b20e315531e45ac9
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/dd06b5f2b09e46fa896ec8fc703572ac
Autor:
Emily Parissa Ghanbari, Kai Jakobs, Marianna Puccini, Leander Reinshagen, Julian Friebel, Arash Haghikia, Nicolle Kränkel, Ulf Landmesser, Ursula Rauch-Kröhnert
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1371 (2023)
Inflammation-induced coagulopathy is a common complication associated with coronavirus disease 2019 (COVID-19). We aim to evaluate the association of NETosis and complement markers with each other as well as their association with thrombogenicity and
Externí odkaz:
https://doaj.org/article/440fcb475f094b16b0292c9d40f839e3
Autor:
Marianna Puccini, Kai Jakobs, Leander Reinshagen, Julian Friebel, Philipp-Alexander Schencke, Emily Ghanbari, Ulf Landmesser, Arash Haghikia, Nicolle Kränkel, Ursula Rauch
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7683 (2023)
Galectin-3 is a beta-galactoside-binding lectin involved in inflammation and lung fibrosis and postulated to enhance thrombosis. In COVID-19, it is considered to be a prognostic marker of severity. The aim of this study was to evaluate whether galect
Externí odkaz:
https://doaj.org/article/07a4233f8a8241a2bc91c3426e04256f
Autor:
Hector Giral, Vedran Franke, Minoo Moobed, Maja F. Müller, Laura Lübking, Divya Maria James, Johannes Hartung, Kira Kuschnerus, Denitsa Meteva, Claudio Seppelt, Philipp Jakob, Roland Klingenberg, Nicolle Kränkel, David Leistner, Tanja Zeller, Stefan Blankenberg, Friederike Zimmermann, Arash Haghikia, Thomas F. Lüscher, Altuna Akalin, Ulf Landmesser, Adelheid Kratzer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inflammasomes are crucial gatekeepers of the immune response, but their maladaptive activation associates with inflammatory pathologies. Besides canonical activation, monocytes can trigger non-transcriptional or rapid inflammasome activation that has
Externí odkaz:
https://doaj.org/article/83cde5d17281485182d722555e086e4e
Autor:
Kai Jakobs, Leander Reinshagen, Marianna Puccini, Julian Friebel, Anne-Christin Beatrice Wilde, Ayman Alsheik, Andi Rroku, Ulf Landmesser, Arash Haghikia, Nicolle Kränkel, Ursula Rauch-Kröhnert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundHemostasis and inflammation are both dysregulated in patients with moderate-to-severe coronavirus disease 2019 (COVID-19). Yet, both processes can also be disturbed in patients with other respiratory diseases, and the interactions between c
Externí odkaz:
https://doaj.org/article/240ff28ed78a47fa82b37668494935f4
Autor:
Ruben A. Jödicke, Shufan Huo, Nicolle Kränkel, Sophie K. Piper, Martin Ebinger, Ulf Landmesser, Agnes Flöel, Matthias Endres, Alexander H. Nave
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: Extracellular vesicles (EV) are sub-1 μm bilayer lipid coated particles and have been shown play a role in long-term cardiovascular outcome after ischemic stroke. However, the dynamic change of EV after stroke and their implications for f
Externí odkaz:
https://doaj.org/article/34d1128cd443468e8fbc33fc40c95200
Autor:
Julian Friebel, Eileen Moritz, Marco Witkowski, Kai Jakobs, Elisabeth Strässler, Andrea Dörner, Daniel Steffens, Marianna Puccini, Stella Lammel, Rainer Glauben, Franziska Nowak, Nicolle Kränkel, Arash Haghikia, Verena Moos, Heinz-Peter Schutheiss, Stephan B. Felix, Ulf Landmesser, Bernhard H. Rauch, Ursula Rauch
Publikováno v:
Cells, Vol 10, Iss 12, p 3517 (2021)
Background: Protease-activated receptor 1 (PAR1) and toll-like receptors (TLRs) are inflammatory mediators contributing to atherogenesis and atherothrombosis. Vorapaxar, which selectively antagonizes PAR1-signaling, is an approved, add-on antiplatele
Externí odkaz:
https://doaj.org/article/c8594175c3e34c72945b83a56f22566c
Autor:
Fatih Yergöz, Julian Friebel, Nicolle Kränkel, Ursula Rauch-Kroehnert, Heinz-Peter Schultheiss, Ulf Landmesser, Andrea Dörner
Publikováno v:
Cells, Vol 10, Iss 8, p 2130 (2021)
Adenine nucleotide translocase 1 (ANT1) transfers ATP and ADP over the mitochondrial inner membrane and thus supplies the cell with energy. This study analyzed the role of ANT1 in the immune response of ischemic heart tissue. Ischemic ANT1 overexpres
Externí odkaz:
https://doaj.org/article/1d0652c371f84dd6947cb96886023ed4
Autor:
Elisabeth Tamara Strässler, Katriina Aalto-Setälä, Mostafa Kiamehr, Ulf Landmesser, Nicolle Kränkel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Induced pluripotent stem cells (iPSCs) avoid many of the restrictions that hamper the application of human embryonic stem cells: limited availability of source material due to legal restrictions in some countries, immunogenic rejection and ethical co
Externí odkaz:
https://doaj.org/article/08541e2ad62d411eb72fbb0fc4cb7567