Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicoline W. Thorsen"'
Publikováno v:
Jensen, M, Thorsen, N W, Hallberg, L A E, Hägglund, P & Hawkins, C L 2023, ' New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers ', Free Radical Biology and Medicine, vol. 202, pp. 97-109 . https://doi.org/10.1016/j.freeradbiomed.2023.03.025
Neutrophil extracellular trap (NET) release plays a key role in many chronic disease settings, including atherosclerosis. They are critical to innate immune defence, but also contribute to disease by promoting thrombosis and inflammation. Macrophages
Mapping the modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl)
Publikováno v:
Hallberg, L A E, Thorsen, N W, Hartsema, E A, Hägglund, P M & Hawkins, C L 2022, ' Mapping the modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl) ', Free Radical Biology and Medicine, vol. 192, pp. 152-164 . https://doi.org/10.1016/j.freeradbiomed.2022.09.016
Histones are critical for the packaging of nuclear DNA and chromatin assembly, which is facilitated by the high abundance of Lys and Arg residues within these proteins. These residues are also the site of a range of post-translational modifications,