Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicolie Young"'
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23252 (2011)
NK cells kill target cells mainly via exocytosis of granules containing perforin (perf) and granzymes (gzm). In vitro, gzm delivery into the target cell cytosol results in apoptosis, and induction of apoptosis is severely impaired in the absence of g
Externí odkaz:
https://doaj.org/article/c3361fd38f2b47f5b9389d6227a5ec61
Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses
Publikováno v:
Antiviral Research. 69:31-38
Many viruses, including flaviviruses, display affinity for cell surface heparan sulfate (HS) proteoglycans with biological relevance in virus attachment/entry. This raises the possibility of the application of HS mimetics in antiviral therapy. We hav
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23252 (2011)
PLoS ONE
PLoS ONE
NK cells kill target cells mainly via exocytosis of granules containing perforin (perf) and granzymes (gzm). In vitro, gzm delivery into the target cell cytosol results in apoptosis, and induction of apoptosis is severely impaired in the absence of g
Autor:
Joseph A. Trapani, Lisa Pavlinovic, Arno Müllbacher, Aulikki Koskinen, Nicolie Young, Matthias Regner
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 183(1)
Cytotoxic T (Tc) cells lyse target cells via exocytosis of granules containing perforin (perf) and granzymes (gzm). In vitro, gzm delivery into the target cell cytosol results in apoptosis, and in the absence of gzm A and B the induction of apoptosis