Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicolette M Johnson"'
Autor:
Young-Jun Choi, Melissa S. Kim, Joshua H. Rhoades, Nicolette M. Johnson, Corbett T. Berry, Sarah Root, Qijun Chen, Yuhua Tian, Rafael J. Fernandez, III, Zvi Cramer, Stephanie Adams-Tzivelekidis, Ning Li, F. Brad Johnson, Christopher J. Lengner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 451-472 (2023)
Background & Aims: Dyskeratosis congenita (DC) is a telomere biology disorder caused primarily by mutations in the DKC1 gene. Patients with DC and related telomeropathies resulting from premature telomere dysfunction experience multiorgan failure. In
Externí odkaz:
https://doaj.org/article/097aee7b209740a1bf70038743eb0b74
Understanding how macroautophagy/autophagy contributes to tissue homeostasis is essential for understanding organismal health. The intestinal epithelium is an ideal model to define mechanisms that regulate tissue homeostasis because it houses well-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae245c003ed16850375fe6ef989fc91
Autor:
Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams‐Tzivelekidis, Yuhua Tian, Patrick A Williams, N Adrian Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton
Publikováno v:
EMBO reports. 23(11)
The intestinal epithelium exhibits a rapid and efficient regenerative response to injury. Emerging evidence supports a model where plasticity of differentiated cells, particularly those in the secretory lineages, contributes to epithelial regeneratio
Autor:
Christopher J. Lengner, Corbett T. Berry, Joshua H. Rhoades, Stephanie Adams-Tzivelekidis, Zvi Cramer, F. Brad Johnson, Qijun Chen, Youngjun Choi, Nicolette M. Johnson, Melissa S. Kim, Sarah Root, Rafael Fernandez, Yuhua Tian, Ning Li
Patients with dyskeratosis congenita (DC) and related telomeropathies resulting from premature telomere dysfunction suffer from multi-organ failure. In the liver, DC patients present with nodular hyperplasia, steatosis, inflammation, and cirrhosis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabf41108c7a36495a0b9a59caa39c65
https://doi.org/10.1101/2021.11.19.469258
https://doi.org/10.1101/2021.11.19.469258
Autor:
Orith Waisbourd-Zinman, Gauri Khandekar, Jessica Llewellyn, Neil D. Theise, Rebecca G. Wells, Pierre Russo, Xiao Liu, Alyssa Kriegermeier, Tatiana Kisseleva, Roquibat Giwa, Yu Du, Nicolette M. Johnson
Publikováno v:
J Hepatol
Background & AimsThe extrahepatic bile duct is the primary tissue initially affected by the cholangiopathy biliary atresia. Biliary atresia affects neonates exclusively and current animal models suggest that the developing bile duct is uniquely susce
Publikováno v:
Developmental Cell. 55:113-115
MTORC1 activity is critical for tissue regeneration in multiple organs and contexts. In this issue of Developmental Cell, Miao et al. describe upstream regulators of mTORC1 activity which promote paligenosis, a process where mature cells de-different
Autor:
Christopher J. Miller, Ying Zheng, Thomas H. Leung, Misha Rosenbach, Denis H. Y. Leung, Casey A. Spencer, Hali S. Kim, Nicolette M. Johnson, Donna M. Brennan-Crispi, George Cotsarelis, Jenny J. Wei
Publikováno v:
Sci Immunol
Adult mammalian wounds, with rare exception, heal with fibrotic scars that severely disrupt tissue architecture and function. Regenerative medicine seeks methods to avoid scar formation and restore the original tissue structures. We show that pharmac
Autor:
Nicolette M, Johnson, Jeeyoon, Na, Keara E, Monaghan, Alan T, Tang, Yuhua, Tian, Nicolae A, Leu, Ning, Li, Mark L, Kahn, Christopher J, Lengner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology. 14:1334-1337.e1