Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicolette Fonseca"'
Autor:
Alexander W. Wyatt, Andrew J. Murtha, Arkhjamil Angeles, Arshia Beigi, Amanda Wong, Gang Wang, Steven Yip, Cameron Herberts, Daniel Khalaf, Elena Schönlau, Kevin Beja, Elie Ritch, Nicolette Fonseca, Matti Annala, Simon Yuen Fai Fu, Evan W. Warner, Kim N. Chi, Gillian Vandekerkhove
Publikováno v:
Clinical Cancer Research. 27:1650-1662
Purpose: DNA damage repair (DDR) defects are common across cancer types and can indicate therapeutic vulnerability. Optimal exploitation of DDR defects in prostate cancer requires new diagnostic strategies and a better understanding of associated cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7aff2192dcc596e5daeb5a50db2c4f
https://doi.org/10.1158/1078-0432.ccr-20-3708
https://doi.org/10.1158/1078-0432.ccr-20-3708
Autor:
Corinne Maurice-Dror, Nicolette Fonseca, Cameron Herberts, Edmond Michael Kwan, Catarina Kollmannsberger, Wilson Tu, Daniel Joseph Khalaf, Matti Annala, Elena Schönlau, Cecily Q. Bernales, Gráinne Donnellan, Joanna Vergidis, Krista Noonan, Daygen L. Finch, Muhammad Zulfiqar, Miller Stacy, Alexander William Wyatt, Kim N. Chi
Publikováno v:
Journal of Clinical Oncology. 40:5055-5055
5055 Background: Deleterious alterations in tumor suppressor genes (TSGs) TP53, RB1, and PTEN are potential markers of small cell neuroendocrine prostate cancer (SCNP), and androgen receptor pathway inhibitor (ARPI) resistance. We examined the outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff68250a103e47ebc061da4411dbcbb5
https://doi.org/10.1200/jco.2022.40.16_suppl.5055
https://doi.org/10.1200/jco.2022.40.16_suppl.5055
Publikováno v:
Transl Androl Urol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b5273565054474418fc7ac15ef1c67
https://pubmed.ncbi.nlm.nih.gov/34804843
https://pubmed.ncbi.nlm.nih.gov/34804843
Functional specialization of intestinal dendritic cell subsets during Th2 helminth infection in mice
Autor:
Stephen A. Redpath, Graham Heieis, Georgia Perona-Wright, Nicolette Fonseca, Sandra S.Y. Kim, Lisa A. Reynolds
Publikováno v:
European Journal of Immunology. 48:87-98
Dendritic cells (DCs) are essential in dictating the nature and effectiveness of immune responses. In the intestine DCs can be separated into discrete subsets, defined by expression of CD11b and CD103, each with different developmental requirements a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7504917010b9236187c3f95e7a48c8a6
https://doi.org/10.1002/eji.201747073
https://doi.org/10.1002/eji.201747073
Autor:
Nicolette Fonseca, William Fan, Cameron Herberts, Alexander W. Wyatt, Corinne Maurice-Dror, Kim N. Chi
Publikováno v:
Journal of Clinical Oncology. 39:5049-5049
5049 Background: CtDNA% (the tumour-derived proportion of cell-free DNA (cfDNA)) is abundant in >60% of mCRPC pts and associates with adverse clinical prognostic factors. However, prognostic associations have not been comprehensively tested across cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e936f63fb602a1dc91d131464e1196e6
https://doi.org/10.1200/jco.2021.39.15_suppl.5049
https://doi.org/10.1200/jco.2021.39.15_suppl.5049
Publikováno v:
Parasite immunology. 36(6)
The host response to infection requires an immune response to be strong enough to control the pathogen but also restrained, to minimize immune-mediated pathology. The conflicting pressures of immune activation and immune suppression are particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40e859d5065967974e5976b663b62ff
https://pubmed.ncbi.nlm.nih.gov/24666543
https://pubmed.ncbi.nlm.nih.gov/24666543
Publikováno v:
Cytokine. 76:110-111
The Influenza A virus causes severe respiratory infections that are a major health problem on a global scale. Annual outbreaks of influenza result in up to 8000 deaths in Canada each year, especially affecting the elderly, the young and others with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd72611e72a7209a26f260cc93ae60f
https://doi.org/10.1016/j.cyto.2015.08.250
https://doi.org/10.1016/j.cyto.2015.08.250
Autor:
Stephen A. Redpath, Lisa A. Reynolds, Graham Heieis, Nicolette Fonseca, Georgia Perona-Wright
Publikováno v:
Cytokine. 76:110
Dendritic cells are key to the initiation and regulation of immune responses. In the gut there are three distinct dendritic cell (DC) subsets, defined by CD11b and CD103, each with different developmental requirements and distinct functional potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cccd567cea77e9f11388c4909885736
https://doi.org/10.1016/j.cyto.2015.08.247
https://doi.org/10.1016/j.cyto.2015.08.247
Publikováno v:
Cytokine. 76:110
Surviving influenza infection requires a careful balance of pro-inflammatory signals that promote viral clearance and anti-inflammatory signals that prevent immunopathology. IL-10 is a potent immunosuppressive cytokine that is essential to this balan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb9ab340f897c2cc7ac77bc56fb300c
https://doi.org/10.1016/j.cyto.2015.08.249
https://doi.org/10.1016/j.cyto.2015.08.249
Publikováno v:
Cytokine. 76:110
Upon activation, CD4+ T cells adopt a highly glycolytic metabolism to meet the increased energy demands of proliferation and cytokine production. It has been reported that different CD4+ T cell subsets exhibit different metabolic profiles, implying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc7cbcd4468e89c1983d4034762de76
https://doi.org/10.1016/j.cyto.2015.08.248
https://doi.org/10.1016/j.cyto.2015.08.248