Nanostructured Dense Collagen‐Polyester Composite Hydrogels as Amphiphilic Platforms for Drug Delivery

Autor: Xiaolin Wang, Olivier Ronsin, Basile Gravez, Nicolette Farman, Tristan Baumberger, Frédéric Jaisser, Thibaud Coradin, Christophe Hélary

Publikováno v: Advanced Science, Vol 8, Iss 7, Pp n/a-n/a (2021)

Abstract Associating collagen with biodegradable hydrophobic polyesters constitutes a promising method for the design of medicated biomaterials. Current collagen‐polyester composite hydrogels consisting of pre‐formed polymeric particles encapsula

Externí odkaz: https://doaj.org/article/4a20ad989914425bbca688615dd8e974

The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis.

Autor: Elodie Bousquet, Min Zhao, André Ly, Guillaume Leroux Les Jardins, Brigitte Goldenberg, Marie-Christine Naud, Laurent Jonet, Bernadette Besson-Lescure, Frederic Jaisser, Nicolette Farman, Yvonne De Kozak, Francine Behar-Cohen

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49036 (2012)

We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular inflammation. The endotoxin-induced uveitis (EIU), a rat model of human intraocular inflammation, w

Externí odkaz: https://doaj.org/article/7bfb709a03424e99b1d667ab4b94afeb

Nanostructured Dense Collagen-Polyester Composite Hydrogels as Amphiphilic Platforms for Drug Delivery

Autor: Olivier Ronsin, Basile Gravez, Xiaolin Wang, Christophe Hélary, Tristan Baumberger, Frederic Jaisser, Thibaud Coradin, Nicolette Farman

Publikováno v: Advanced Science
Advanced Science, 2021, pp.2004213. ⟨10.1002/advs.202004213⟩
Advanced Science, Wiley Open Access, 2021, pp.2004213. ⟨10.1002/advs.202004213⟩
Advanced Science, Vol 8, Iss 7, Pp n/a-n/a (2021)

Associating collagen with biodegradable hydrophobic polyesters constitutes a promising method for the design of medicated biomaterials. Current collagen‐polyester composite hydrogels consisting of pre‐formed polymeric particles encapsulated withi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a65920b0ac855d306fcf51d05ba84bd
https://doi.org/10.1002/advs.202004213

Abstract P2021: Cutaneous Wound Healing in Diabetic Mice is Improved by Topical Mineralocorticoid Receptor Blockade

Autor: Van Tuan Nguyen, Selim Aractingi, Nicolette Farman, Frederic Jaisser

Publikováno v: Hypertension. 74

Introduction: Chronic skin ulcers resulting from impaired wound healing are a serious complication of diabetes. Unresolved inflammation, associated with the dysregulation of both the phenotype and function of macrophages, is involved in the poor heal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80c61db88ddbb92233d20c3877188dde
https://doi.org/10.1161/hyp.74.suppl_1.p2021

11β-HSD2 SUMOylation Modulates Cortisol-induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation

Autor: Frederic Jaisser, Dawn E W Livingstone, Matthew A. Bailey, Alex Odermatt, Nicolette Farman, Ruben Jimenez-Canino, Fabián Lorenzo-Díaz, Diego Alvarez de la Rosa

Publikováno v: Jiménez-Canino, R, Lorenzo-Díaz, F, Odermatt, A, Bailey, M A, Livingstone, D E W, Jaisser, F, Farman, N & Alvarez de la Rosa, D 2017, ' 11β-HSD2 SUMOylation Modulates Cortisol-induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation ', Endocrinology . https://doi.org/10.1210/en.2017-00440

The enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) has an essential role in aldosterone target tissues, conferring aldosterone selectivity for the mineralocorticoid receptor (MR) by converting 11β-hydroxyglucocorticoids to inactive 11-k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a048ba8ff35683c402e6d077da84dfff
https://hdl.handle.net/20.500.11820/5c759c6f-8606-4653-ae8a-52bcc804639e