Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicolette A Zielinski Mozny"'
Autor:
Lauren R. Begg, Adrienne M. Orriols, Markella Zannikou, Chen Yeh, Pranathi Vadlamani, Deepak Kanojia, Rosemary Bolin, Sara F. Dunne, Sanjeev Balakrishnan, Roman Camarda, Diane Roth, Nicolette A. Zielinski-Mozny, Christina Yau, Athanassios Vassilopoulos, Tzu-Hsuan Huang, Kwang-Youn A. Kim, Dai Horiuchi
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-17 (2024)
Abstract Background Understanding why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well remains a challenge. This study aims to understand the potential underlying mechanisms distinguish
Externí odkaz:
https://doaj.org/article/bbe12d3b38a147d5bf67e56921985ad3
Autor:
Athanassios Vassilopoulos, Alesia Vialichka, Erica Fleming-Trujillo, Young Ah Goo, Massimo Cristofanilli, Matthew R. Clutter, Pranathi Vadlamani, Marc L. Mendillo, Jessica N. Perrino, Sara Fernandez Dunne, Michelle Velyunskiy, Diane Roth, Adrienne M. Orriols, Rosemary Bolin, Lauren Begg, Byoung-Kyu Cho, Ratika Kunder, Deepak Kanojia, Nicolette A. Zielinski-Mozny, Dai Horiuchi
Publikováno v:
Cell Chem Biol
Triple-negative breast cancer (TNBC) is the breast cancer subtype with the poorest clinical outcome. The PIM family of kinases has emerged as a factor that is both overexpressed in TNBC and associated with poor outcomes. Preclinical data suggest that
Autor:
Paul W. Hager, Paul V. Phibbs, Tricia C. Maleniak, Carolyn H. MacGregor, Laura J. Runyen-Janecky, Nicolette A. Zielinski-Mozny, Susan E. H. West, Sang-Jin Suh
Publikováno v:
Microbiology. 148:1561-1569
Vfr of Pseudomonas aeruginosa is 91% similar to the cAMP receptor protein (CRP) of Escherichia coli. Based on the high degree of sequence homology between the two proteins, the question arose whether Vfr had a global regulatory effect on gene express
Publikováno v:
Lab animal. 42(2)
Autor:
Stephen K, Tahir, Michael A, Nukkala, Nicolette A, Zielinski Mozny, R Bruce, Credo, Robert B, Warner, Qun, Li, Keith W, Woods, Akiyo, Claiborne, Stephen L, Gwaltney, David J, Frost, Hing L, Sham, Saul H, Rosenberg, Shi-Chung, Ng
Publikováno v:
Molecular cancer therapeutics. 2(3)
In this report, we describe the antitumor activity of A-289099, an indolyloxazoline derivative with antimitotic activity. A-289099 decreased the proliferation of a variety of cells with EC(50) values ranging from 5.1 to 12.8 nM in a P-glycoprotein-in