Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicolette Gouder"'
Autor:
Laetitia Gabernet, Martin Güttinger, Nicolette Gouder, Louis Scheurer, Florence Crestani, Thomas Rülicke, Denise E. Fedele, Detlev Boison
Publikováno v:
Brain. 128:2383-2395
Adenosine kinase (ADK) is considered to be the key regulator of the brain's endogenous anticonvulsant, adenosine. In adult brain, ADK is primarily expressed in a subpopulation of astrocytes and striking upregulation of ADK in these cells has been ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433f57d67b63dde1fbd59eeb53a4d215
https://doi.org/10.1093/brain/awh555
https://doi.org/10.1093/brain/awh555
Publikováno v:
Epilepsia. 44:877-885
Summary: Purpose: Because of the high incidence of pharmacoresistance in the treatment of epilepsy (20–30%), alternative treatment strategies are needed. Recently a proof-of-principle for a new therapeutic approach was established by the intraventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc233da933190848dcd97054dbdd8278
https://doi.org/10.1046/j.1528-1157.2003.03603.x
https://doi.org/10.1046/j.1528-1157.2003.03603.x
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(3)
Endogenous adenosine in the brain is thought to prevent the development and spread of seizures via a tonic anticonvulsant effect. Brain levels of adenosine are primarily regulated by the activity of adenosine kinase. To establish a link between adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea7ff477d51924a0db2c79e47807fab
https://pubmed.ncbi.nlm.nih.gov/14736855
https://pubmed.ncbi.nlm.nih.gov/14736855
Autor:
Detlev Boison, Rainer Klocke, Kristina Becker, Cord-Michael Becker, Julia Brill, Nicolette Gouder, Norbert Klugbauer, Franz Hofmann, Dieter Paul
Publikováno v:
The Journal of biological chemistry. 279(8)
entla (ent) is a novel recessive phenotype of mice. The underlying mutation was mapped to chromosome 9 (60.1 centimorgans) and identified as an allele of the Cacna2d2 gene encoding the alpha2delta-2 subunit of voltage-gated calcium channels. The Cacn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6db4ca6631447b755f500b4270909a
https://pubmed.ncbi.nlm.nih.gov/14660671
https://pubmed.ncbi.nlm.nih.gov/14660671
Autor:
Denise E. Fedele, Nicolette Gouder
Publikováno v:
Brain: A Journal of Neurology; Oct2005, Vol. 128 Issue 10, p2383-2395, 13p