Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nicoletta Sorvillo"'
Autor:
Isabel Arenas Hoyos, Anja Helmer, Anaïs Yerly, Ioana Lese, Stefanie Hirsiger, Lei Zhang, Daniela Casoni, Luisana Garcia, MariaFrancesca Petrucci, Sabine E. Hammer, Tereza Duckova, Yara Banz, Matteo Montani, Mihai Constantinescu, Esther Vögelin, Gregor Bordon, Simone Aleandri, Jean-Christophe Prost, Adriano Taddeo, Paola Luciani, Robert Rieben, Nicoletta Sorvillo, Radu Olariu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe standard treatment for preventing rejection in vascularized composite allotransplantation (VCA) currently relies on systemic immunosuppression, which exposes the host to well-known side effects. Locally administered immunosuppression
Externí odkaz:
https://doaj.org/article/3e407b5b4cfb452a91c1f1944aded4ad
Autor:
Tom Arfman, Valentina Zollet, Nick vanEs, Floris T. M. Bosch, Gerry A. F. Nicolaes, Nicoletta Sorvillo, Jan Voorberg
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 136-140 (2024)
Abstract Neutrophil released peptidyl arginine deiminase 4 (PAD4) converts arginine residues on plasma proteins into citrulline. Here, we developed an assay to quantify citrullinated fibrinogen. We employed a biotin‐conjugated phenylglyoxal (biotin
Externí odkaz:
https://doaj.org/article/81af964bf12e4c81afc00468102d5cf6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Endothelial dysfunction is an early event of vascular injury defined by a proinflammatory and procoagulant endothelial cell (EC) phenotype. Although endothelial glycocalyx disruption is associated with vascular damage, how various inflammato
Externí odkaz:
https://doaj.org/article/0a7c372a9ffb46298b65497ced1331ef
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The physiological, anti-inflammatory, and anti-coagulant properties of endothelial cells (ECs) rely on a complex carbohydrate-rich layer covering the luminal surface of ECs, called the glycocalyx. In a range of cardiovascular disorders, glycocalyx sh
Externí odkaz:
https://doaj.org/article/652e0d0abd2f40e6a74a84faa1df80db
Autor:
Patrick Münzer, Roberto Negro, Shoichi Fukui, Lucas di Meglio, Karen Aymonnier, Long Chu, Deya Cherpokova, Sarah Gutch, Nicoletta Sorvillo, Lai Shi, Venkat Giri Magupalli, Alexander N. R. Weber, Rüdiger E. Scharf, Clare M. Waterman, Hao Wu, Denisa D. Wagner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophil extracellular trap formation (NETosis) and the NLR family pyrin domain containing 3 (NLRP3) inflammasome assembly are associated with a similar spectrum of human disorders. While NETosis is known to be regulated by peptidylarginine deimina
Externí odkaz:
https://doaj.org/article/2d05e129ea374b9f8cb826c28431c42d
Autor:
Fabian C. Verbij, Nicoletta Sorvillo, Paul H.P. Kaijen, Johana Hrdinova, Ivan Peyron, Rob Fijnheer, Anja ten Brinke, Alexander B. Meijer, Floris P.J. van Alphen, Timo K. van den Berg, Jonas J.H. Graversen, Soren K. Moestrup, Jan Voorberg
Publikováno v:
Blood Advances, Vol 1, Iss 5, Pp 293-305 (2017)
Abstract: Internalization of ADAMTS13 by macrophages may contribute to its clearance from the circulation. Here we investigated endocytic mechanisms that contribute to the uptake of ADAMTS13 by macrophages. Human monocyte-derived macrophages were use
Externí odkaz:
https://doaj.org/article/0e83cb2011d54b119ca1833b16f9349c
Autor:
Thilo Witsch, Kimberly Martinod, Nicoletta Sorvillo, Irina Portier, Simon F. De Meyer, Denisa D. Wagner
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 3 (2018)
BackgroundA disintegrin‐like metalloproteinase with thrombospondin motif type 1 member 13 (ADAMTS13), the von Willebrand factor–cleaving enzyme, decreases leukocyte and platelet recruitment and, thus, reduces thrombosis and inflammation. Recombin
Externí odkaz:
https://doaj.org/article/35fc72c938ad47429f6a03b592e2821a
Autor:
Nicoletta Sorvillo, Robin B. Hartholt, Esther Bloem, Magdalena Sedek, Anja ten Brinke, Carmen van der Zwaan, Floris P. van Alphen, Alexander B. Meijer, Jan Voorberg
Publikováno v:
Haematologica, Vol 101, Iss 3 (2016)
It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derive
Externí odkaz:
https://doaj.org/article/b28ed143071e4b9a842230f9a440e7b1
Autor:
Wouter Pos, Nicoletta Sorvillo, Rob Fijnheer, Hendrik B. Feys, Paul H.P Kaijen, Gestur Vidarsson, Jan Voorberg
Publikováno v:
Haematologica, Vol 96, Iss 11 (2011)
Background The majority of patients diagnosed with thrombotic thrombocytopenic purpura have autoantibodies directed towards the spacer domain of ADAMTS13.Design and Methods In this study we explored the epitope specificity and immunoglobulin class an
Externí odkaz:
https://doaj.org/article/8fc0f4b6bb634dae802129eeb96e189e
Autor:
Krasimir Kolev, Á. Farkas, Balázs Kiss, Imre Varjú, Deya Cherpokova, Veronika J. Farkas, Attila Bóta, Colin Longstaff, Erzsébet Komorowicz, Nicoletta Sorvillo, Tímea Feller, András Wacha, László Szabó, Denisa D. Wagner, Miklós Z. Kellermayer
Publikováno v:
Circulation Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446b14f2932991fcbc68704f48a006f0
https://doi.org/10.1161/circresaha.121.319061
https://doi.org/10.1161/circresaha.121.319061