Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Nicoletta Kessaris"'
Autor:
Lorenza Magno, Zeinab Asgarian, Migle Apanaviciute, Yasmin Milner, Nora Bengoa-Vergniory, Anna Noren Rubin, Nicoletta Kessaris
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Cre transgene-based fate mapping in mice reveals that most septal neurons originate from progenitor domains in the septum and identifies Bsx as an embryonic marker and essential regulator of glutamatergic neuron development and locomotion behaviour.
Externí odkaz:
https://doaj.org/article/46ce62f914df4e1290d81a4df49037b2
Autor:
Zeinab Asgarian, Marcio Guiomar Oliveira, Agata Stryjewska, Ioannis Maragkos, Anna Noren Rubin, Lorenza Magno, Vassilis Pachnis, Mohammadmersad Ghorbani, Scott Wayne Hiebert, Myrto Denaxa, Nicoletta Kessaris
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
There is a large diversity of inhibitory interneurons in the mammalian cerebral cortex. How this emerges during embryogenesis remains unclear. Here, the authors identify MTG8 as a co-factor of LHX6 and a new regulator of cortical interneuron developm
Externí odkaz:
https://doaj.org/article/00979fa66fb446ab972a14461acf5a6a
Autor:
Lorenza Magno, Zeinab Asgarian, Valentina Pendolino, Theodora Velona, Albert Mackintosh, Flora Lee, Agata Stryjewska, Celine Zimmer, François Guillemot, Mark Farrant, Beverley Clark, Nicoletta Kessaris
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109249- (2021)
Summary: Cortical GABAergic interneurons are generated in large numbers in the ganglionic eminences and migrate into the cerebral cortex during embryogenesis. At early postnatal stages, during neuronal circuit maturation, autonomous and activity-depe
Externí odkaz:
https://doaj.org/article/e2d0408bf0594de0a7200913d8bf8c4f
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 793-802 (2019)
Summary: Oriens lacunosum-moleculare (O-LM) interneurons constitute 40% of hippocampal interneurons expressing Somatostatin (SST). Recent evidence has indicated a dual origin for these cells in the medial and caudal ganglionic eminences (MGE and CGE)
Externí odkaz:
https://doaj.org/article/169d175e91ea479dac6f2012566036a9
Autor:
Lorenza Magno, Caswell Barry, Christoph Schmidt-Hieber, Polyvios Theodotou, Michael Häusser, Nicoletta Kessaris
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1572-1584 (2017)
The transcription factor NKX2-1 is best known for its role in the specification of subsets of cortical, striatal, and pallidal neurons. We demonstrate through genetic fate mapping and intersectional focal septal deletion that NKX2-1 is selectively re
Externí odkaz:
https://doaj.org/article/312dd285d5d04ed3ae8c4d8bc3ebe2d0
Autor:
Kenneth D Harris, Hannah Hochgerner, Nathan G Skene, Lorenza Magno, Linda Katona, Carolina Bengtsson Gonzales, Peter Somogyi, Nicoletta Kessaris, Sten Linnarsson, Jens Hjerling-Leffler
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2006387 (2018)
Understanding any brain circuit will require a categorization of its constituent neurons. In hippocampal area CA1, at least 23 classes of GABAergic neuron have been proposed to date. However, this list may be incomplete; additionally, it is unclear w
Externí odkaz:
https://doaj.org/article/ccf484a2854f4fbdad2326e2044d9008
Autor:
Neal Anthwal, Michelle Pelling, Suzanne Claxton, Georg Mellitzer, Caitlin Collin, Nicoletta Kessaris, William D. Richardson, Gérard Gradwohl, Siew-Lan Ang
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 5, Pp 1133-1145 (2013)
SUMMARY The ventral hypothalamus acts to integrate visceral and systemic information to control energy balance. The basic helix-loop-helix transcription factor neurogenin-3 (Ngn3) is required for pancreatic β-cell development and has been implicated
Externí odkaz:
https://doaj.org/article/5f550611b1a74183bc5fedc179c29251
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
The proper function of the CNS requires the correct integration of glutamatergic neurons and GABAergic interneurons. Cortical GABAergic interneurons are characterized by extraordinary neurochemical and functional diversity. Although recent studies ha
Externí odkaz:
https://doaj.org/article/e02d3a3b3ae2437e9779265eb2fa2f94
Autor:
Anna Noren Rubin, Nicoletta Kessaris
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77339 (2013)
The homeobox-encoding gene Prox1 and its Drosophila homologue prospero are key regulators of cell fate-specification. In the developing rodent cortex a sparse population of cells thought to correspond to late-generated cortical pyramidal neuron precu
Externí odkaz:
https://doaj.org/article/583f0b335e28489694ca51a42416bfdb
Autor:
Frédéric Causeret, Monica Ensini, Anne Teissier, Nicoletta Kessaris, William D Richardson, Thibaut Lucas de Couville, Alessandra Pierani
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19367 (2011)
Development of the vertebrate forebrain and craniofacial structures are intimately linked processes, the coordinated growth of these tissues being required to ensure normal head formation. In this study, we identify five small subsets of progenitors
Externí odkaz:
https://doaj.org/article/23faa8afe08f41efbde7bd175a665c5f