Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nicoletta Eliopoulos"'
Autor:
Maria Petropavlovskaia, Beatrice Assouline-Thomas, Jessica Cuerquis, Jing Zhao, Shaun Violette-Deslauriers, Eni Nano, Nicoletta Eliopoulos, Lawrence Rosenberg
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35372- (2024)
Mesenchymal stem/stromal cells (MSCs) are emerging as a new therapy for diabetes. Here we investigate the properties of MSCs engineered to express Islet Neogenesis Associated Protein (INGAP) previously shown to reverse diabetes in animal models and e
Externí odkaz:
https://doaj.org/article/f41f8cdf79f647ae8031aed30ac59381
Autor:
Natasha Salame, Jean-Pierre Bikorimana, Nehme El-Hachem, Wael Saad, Mazen Kurdi, Jing Zhao, Nicoletta Eliopoulos, Riam Shammaa, Moutih Rafei
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background Mesenchymal stromal cells (MSCs) have been extensively used in the clinic due to their exquisite tissue repair capacity. However, they also hold promise in the field of cellular vaccination as they can behave as conditional antige
Externí odkaz:
https://doaj.org/article/fffee480623141a1968e76cc81908d9e
Autor:
Jean-Pierre Bikorimana, Nehme El-Hachem, Jamilah Abusarah, Nicoletta Eliopoulos, Sebastien Talbot, Riam Shammaa, Moutih Rafei
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105537- (2022)
Summary: Immunoproteasome-reprogrammed mesenchymal stromal cells (IRMs) can surpass dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination regimen remains clinically unsuitable due to the relatively high dose of IR
Externí odkaz:
https://doaj.org/article/ca5732deff804308b5e2a158b4707052
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has marked adverse effects on patient quality of life and cancer the
Externí odkaz:
https://doaj.org/article/90b832c5128647efbc1a06739218e188
Autor:
Diana M Iglesias, Reyhan El-Kares, Anna Taranta, Francesco Bellomo, Francesco Emma, Martine Besouw, Elena Levtchenko, Jaan Toelen, Lambertus van den Heuvel, Leelee Chu, Jing Zhao, Yoon Kow Young, Nicoletta Eliopoulos, Paul Goodyer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42840 (2012)
Cystinosis is a rare disease caused by homozygous mutations of the CTNS gene, encoding a cystine efflux channel in the lysosomal membrane. In Ctns knockout mice, the pathologic intralysosomal accumulation of cystine that drives progressive organ dama
Externí odkaz:
https://doaj.org/article/353a18b5afee4d52adc1fd7c0dda280d
Autor:
Jean-Pierre, Bikorimana, Nehme, El-Hachem, Jamilah, Abusarah, Nicoletta, Eliopoulos, Sebastien, Talbot, Riam, Shammaa, Moutih, Rafei
Publikováno v:
iScience. 25(12)
Immunoproteasome-reprogrammed mesenchymal stromal cells (IRMs) can surpass dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination regimen remains clinically unsuitable due to the relatively high dose of IRMs needed
Autor:
Jean Pierre Bikorimana, Nehme El-Hachem, Jamilah Abusarah, Nicoletta Eliopoulos, Sebastien Talbot, Riam Shammaa, Moutih Rafei
Publikováno v:
SSRN Electronic Journal.
Autor:
Jean-Pierre Bikorimana, Jing Zhao, Riam Shammaa, Mazen Kurdi, Wael Saad, Nicoletta Eliopoulos, Natasha Salame, Moutih Rafei, Nehme El-Hachem
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Background Mesenchymal stromal cells (MSCs) have been extensively used in the clinic due to their exquisite tissue repair capacity. However, they also hold promise in the field of cellular vaccination as they can behave as conditional antigen present
Autor:
Fiona Lau, Jing Zhao, Yu Ling Zhang, Benjamin Dalisson, Nicoletta Eliopoulos, Jake E. Barralet
Publikováno v:
Advanced biosystems. 4(11)
This study determines whether the viability of mesenchymal stem cell (MSC) in vitro is most sensitive to oxygen supply, energetic substrate supply, or accumulation of lactate. Mouse unmodified (wild type (WT)) and erythropoietin (EPO) gene-modified M
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Cells mobilized from the bone marrow can contribute to endothelial regeneration and repair. Nevertheless, cardiovascular diseases are associated with diminished numbers and function of these cells, attenuating their healing potential. Gene transfer o