Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicole Zinger"'
Autor:
Melanie Marcille, Sandra Hurtado Rúa, Charles Tyshkov, Abhishek Jaywant, Joseph Comunale, Ulrike W. Kaunzner, Nancy Nealon, Jai S. Perumal, Lily Zexter, Nicole Zinger, Olivia Bruvik, Yi Wang, Elizabeth Sweeney, Amy Kuceyeski, Thanh D. Nguyen, Susan A. Gauthier
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Quantitative susceptibility mapping (QSM), an imaging technique sensitive to brain iron, has been used to detect paramagnetic rims of iron-laden active microglia and macrophages in a subset of multiple sclerosis (MS) lesions, known as rim+ l
Externí odkaz:
https://doaj.org/article/4ef6e94e55394aebb8a3b3f194aec9b7
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1755-1759 (2021)
Abstract The objective of this pilot study was to assess a 2‐year change in innate immune burden in 15 progressive multiple sclerosis (MS) patients using PK11195‐PET. Sixteen age‐matched healthy controls (HC) were included for baseline comparis
Externí odkaz:
https://doaj.org/article/f6d5c88a07614bbea10c13a0ed3a23be
Autor:
Ceren Tozlu, Keith Jamison, Thanh Nguyen, Nicole Zinger, Ulrike Kaunzner, Sneha Pandya, Yi Wang, Susan Gauthier, Amy Kuceyeski
Publikováno v:
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background In people with multiple sclerosis (pwMS), lesions with a hyperintense rim (rim+) on Quantitative Susceptibility Mapping (QSM) have been shown to have greater myelin damage compared to rim‐ lesions, but their association with dis
Externí odkaz:
https://doaj.org/article/4c315457e6ee4a13ba3d1c6a8579e208
Autor:
Ceren Tozlu, Emily Olafson, Keith Jamison, Emily Demmon, Ulrike Kaunzner, Melanie Marcille, Nicole Zinger, Nara Michaelson, Neha Safi, Thanh Nguyen, Susan Gauthier, Amy Kuceyeski
Publikováno v:
bioRxiv
ObjectivePrediction of disease progression is challenging in multiple sclerosis (MS) as the sequence of lesion development and retention of inflammation within a subset of chronic lesions is heterogeneous among patients. We investigated the sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f15eae5b7f9c9286fefc14431202e2
https://doi.org/10.1101/2023.01.26.525537
https://doi.org/10.1101/2023.01.26.525537
Autor:
Nicole Zinger, Gerald Ponath, Elizabeth Sweeney, Thanh D. Nguyen, Chih Hung Lo, Ivan Diaz, Alexey Dimov, Leilei Teng, Lily Zexter, Joseph Comunale, Yi Wang, David Pitt, Susan A. Gauthier
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
BACKGROUND AND OBJECTIVES: To determine the effects of dimethyl fumarate (DMF) and glatiramer acetate on iron content in chronic active lesions in patients with multiple sclerosis (MS) and in human microglia in vitro. METHODS: This was a retrospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60b4e044a911b9132c855006fba1827
https://hdl.handle.net/10356/164429
https://hdl.handle.net/10356/164429
Autor:
Ulrike W. Kaunzner, Sandra M. Hurtado Rúa, Joseph P. Comunale, Amy Kuceyeski, Thanh D. Nguyen, Melanie Marcille, Elizabeth M. Sweeney, Charles Tyshkov, Olivia Bruvik, Lily Zexter, Nicole Zinger, Abhishek Jaywant, Nancy N Nealon, Yi Wang, Jai S. Perumal, Susan A. Gauthier
Publikováno v:
Scientific reports. 12(1)
Quantitative susceptibility mapping (QSM), an imaging technique sensitive to brain iron, has been used to detect paramagnetic rims of iron-laden active microglia and macrophages in a subset of multiple sclerosis (MS) lesions, known as rim+ lesions, t
Autor:
Keith Jamison, Thanh D. Nguyen, Yi Wang, Amy Kuceyeski, Ceren Tozlu, Sneha Pandya, Ulrike W. Kaunzner, Susan A. Gauthier, Nicole Zinger
Publikováno v:
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Brain and Behavior
Brain and Behavior
Background In people with multiple sclerosis (pwMS), lesions with a hyperintense rim (rim+) on Quantitative Susceptibility Mapping (QSM) have been shown to have greater myelin damage compared to rim‐ lesions, but their association with disability h
Autor:
Amy Kuceyeski, Ceren Tozlu, Susan A. Gauthier, Nicole Zinger, Ulrike W. Kaunzner, Yi Wang, Sneha Pandya, Keith Jamison, Thanh N. Nguyen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebbc61569db36c572dc1a8efc9a6e3b7
https://doi.org/10.1002/brb3.2353/v2/response1
https://doi.org/10.1002/brb3.2353/v2/response1
Autor:
Nicole Zinger, Ilhami Kovanlikaya, Pascal Spincemaille, Elizabeth M. Sweeney, Susan A. Gauthier, Alexey Dimov, Brian H. Kopell, Yi Wang, Thanh D. Nguyen
Publikováno v:
J Neuroimaging
BACKGROUND AND PURPOSE: The objective ofthis study was to demonstrate a global cerebrospinal fluid (CSF) method for a consistent and automated zero referencing of brain quantitative susceptibility mapping (QSM). METHODS: Whole brain CSF mask was auto
Autor:
Sandra M. Hurtado Rúa, Susan A. Gauthier, Bruvik O, Thanh D. Nguyen, Amy Kuceyeski, Joseph P. Comunale, Jai Perumal, Ulrike W. Kaunzner, Elizabeth M. Sweeney, Nicole Zinger, Tyshkov C, Lily Zexter, Yi Wang, Nancy N Nealon, Melanie Marcille, Abhishek Jaywant
ObjectiveThis study aimed to explore the association between chronic active rim+ lesions, identified as having a hyperintense rim on quantitative susceptibility mapping (QSM), on both clinical disability and imaging measures of neurodegeneration in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5785be8b992f7cef279b496b094f2404
https://doi.org/10.1101/2021.05.29.21257734
https://doi.org/10.1101/2021.05.29.21257734