Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicole Wretham"'
Autor:
Abdulaziz Alhussan, Nolan Jackson, Norman Chow, Ermias Gete, Nicole Wretham, Nancy Dos Santos, Wayne Beckham, Cheryl Duzenli, Devika B. Chithrani
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 713 (2024)
This research underscores the potential of combining nanotechnology with conventional therapies in cancer treatment, particularly for challenging cases like pancreatic cancer. We aimed to enhance pancreatic cancer treatment by investigating the syner
Externí odkaz:
https://doaj.org/article/da12d4fe204b42e1b9d76ee5d42418a7
Autor:
Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is as
Externí odkaz:
https://doaj.org/article/a628231eefc547ca89a67c8ce3fcdf31
Autor:
Courtney van Ballegooie, Nicole Wretham, Tanya Ren, Ioana-Mihaela Popescu, Donald T. Yapp, Marcel B. Bally
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1831 (2022)
Zein can be utilized to form nanoscale particles for drug delivery applications. Despite the ease of synthesis, these particles often aggregate when exposed to physiologically relevant conditions (e.g., pH and salt concentrations). This instability h
Externí odkaz:
https://doaj.org/article/eb980ce762fe45bcbfaa86d0e5df9aba
Autor:
Ada W.Y. Leung, Kent T.J. Chen, Gemma M. Ryan, Malathi Anantha, Nicole Wretham, Zeynab Nosrati, Devon Heroux, Linchuan Wang, Norman Chow, Zhongye Dai, Marcel B. Bally
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 345
CX5461, a compound initially identified as an RNA polymerase inhibitor and more recently as a G-quadruplex binder, binds copper to form a complex. Our previous publication showed that the complexation reaction can be leveraged to formulate copper-CX5
Autor:
Tia Dash, Katy Milne, Basile Tessier-Cloutier, Elizabeth C. Halvorsen, Nancy Erro Go, Norman S. Chow, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Dos Santos, Nicole Wretham, Maryam Osooly, Brad H. Nelson, Sharon M. Gorski, Chandra Lebovitz, Marcel B. Bally, Wan L. Lam, Shelby Thornton, Kevin L. Bennewith, Rachel A. Cederberg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is associated
Autor:
Daisuke Ennishi, Robert S. Molday, Robert Kridel, Graham W. Slack, Barbara Meissner, Allen W. Zhang, Christoffer Hother, Laurie L. Molday, Joseph M. Connors, Ali Bashashati, Libin Abraham, Nancy Dos Santos, Adele Telenius, Saeed Saberi, Michael Y. Li, Michael R. Gold, Andrew J. Mungall, Randy D. Gascoyne, Pedro Farinha, Daniel Lai, Da Wei Huang, Marco A. Marra, Lauren Chong, Diego Villa, Nicole Wretham, Christian Steidl, Brianna N. Bristow, Fong Chun Chan, Louis M. Staudt, Natasja N. Viller, Christopher Rushton, Alina S. Gerrie, Sohrab P. Shah, Shannon Healy, Elena Viganò, Sara Mostafavi, Abigail Baticados, Ryan D. Morin, Derek S. Chiu, Gerben Duns, Anja Mottok, Susana Ben-Neriah, Gabriela V. Cohen Freue, Sohrab Salehi, David Scott, Katsuyoshi Takata, Merrill Boyle, Kerry J. Savage, Bruce Woolcock, Laurie H. Sehn, Angel Madero, Robert A. Uger, Hennady P. Shulha, Andrew P. Weng, Marcel B. Bally, Mark Wong, Tomohiro Aoki
Publikováno v:
Nat Med
Transmembrane protein 30A (TMEM30A) maintains the asymmetric distribution of phosphatidylserine, an integral component of the cell membrane and ‘eat-me’ signal recognized by macrophages. Integrative genomic and transcriptomic analysis of diffuse