Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging

Autor: Corina T. Madreiter-Sokolowski, Markus Waldeck-Weiermair, Marie-Pierre Bourguignon, Nicole Villeneuve, Benjamin Gottschalk, Christiane Klec, Sarah Stryeck, Snjezana Radulovic, Warisara Parichatikanond, Saša Frank, Tobias Madl, Roland Malli, Wolfgang F. Graier

Publikováno v: Redox Biology, Vol 20, Iss , Pp 458-466 (2019)

Background: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxyge

Externí odkaz: https://doaj.org/article/f1455c7fc7a64f4581c789ca027a95e2

P2 LOCAL ABDOMINAL VERSUS THORACIC AORTA STIFFENING IN HYPERTENSIVE RATS UNDER EITHER NO RESTRICTION OR SALTED DIET

Autor: George Lindesay, Neila Malti, Christophe Ragonnet, Marc Isabelle, Nicole Villeneuve, Yvonnick Bézie, Christine Vayssettes-Courchay

Publikováno v: Artery Research, Vol 20 (2017)

Background: Hypertensive humans exhibit reduced nitric oxide bioavailability and increased salt sensitivity, both of which are related to central artery stiffening. We studied the effect of 5 week NO restriction via L-NAME treatment in spontaneously

Externí odkaz: https://doaj.org/article/0f572dfe8d3e426e957a6d3db8534f88

P1.5 AGE AND HYPERTENSION STRONGLY REDUCE AORTIC VISCO-ELASTIC PROPERTIES IN RATS AT BASAL AND MATCHED BLOOD PRESSURE LEVELS

Autor: George Lindesay, Christophe Ragonnet, Stefano Chimenti, Nicole Villeneuve, Christine Vayssettes-Courchay

Publikováno v: Artery Research, Vol 12 (2015)

Age and hypertension are major causes of large artery stiffening, a cardiovascular risk factor for heart and kidney damage. Long term hypertension induces vascular remodeling, accelerating vascular aging. The aged Spontaneously Hypertensive Rat (SHR)

Externí odkaz: https://doaj.org/article/5af4dd4651724e9da6a8c39777e3f074

Differential Stiffening between the Abdominal and Thoracic Aorta: Effect of Salt Loading in Stroke-Prone Hypertensive Rats

Autor: Christine Vayssettes-Courchay, Yvonnick Bézie, Chandima Dharmasena, Nicole Villeneuve, Véronique Duchatelle, George Lindesay, Christophe Ragonnet

Publikováno v: Journal of Vascular Research. 55:144-158

Central artery stiffening is recognized as a cardiovascular risk. The effects of hypertension and aging have been shown in human and animal models but the effect of salt is still controversial. We studied the effect of a high-salt diet on aortic stif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52de9c8594e29d96b34778b673cbe94e
https://doi.org/10.1159/000488877

Le système lymphatique cardiaque

Autor: Barbara Garmy-Susini, Ebba Brakenhielm, Nicole Villeneuve, Nathalie Pizzinat, Antoine Bril, Angelo Parini

Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2017, 33 (8-9), pp.765-770. ⟨10.1051/medsci/20173308022⟩
médecine/sciences, 2017, 33 (8-9), pp.765-770. ⟨10.1051/medsci/20173308022⟩

International audience; > Le système lymphatique est un réseau vas-culaire responsable du transport des graisses intestinales. Il participe à la surveillance immune et permet le maintien de l'homéostasie tissu-laire. Malgré un grand nombre d'év

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645f8703879312155c2b08104c09a886
https://doi.org/10.1051/medsci/20173308022