Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicole V. Warrington"'
Autor:
David T Fox, Emily N Schmidt, Hongzhao Tian, Suraj Dhungana, Michael C Valentine, Nicole V Warrington, Paul D Phillips, Kellan B Finney, Emily K Cope, Jeff G Leid, Charles A Testa, Andrew T Koppisch
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95271 (2014)
Fosmidomycin is a time-dependent nanomolar inhibitor of methylerythritol phosphate (MEP) synthase, which is the enzyme that catalyzes the first committed step in the MEP pathway to isoprenoids. Importantly, fosmidomycin is one of only a few MEP pathw
Externí odkaz:
https://doaj.org/article/9f74c1a2a0db47f1993e3256248be398
Autor:
Wayne F. Anderson, Ryan J. Vierling, J M Smith, Caren L. Freel Meyers, Andrew T. Koppisch, Misty L. Kuhn, Nicole V. Warrington
Publikováno v:
The Journal of antibiotics
The unique methylerythritol phosphate (MEP) pathway for isoprenoid biosynthesis is essential in most bacterial pathogens. The first enzyme in this pathway, 1-deoxy-D-xylulose 5-phosphate (DXP) synthase, catalyzes a distinct thiamin diphosphate (ThDP)
Autor:
Emily N. Schmidt, Hongzhao Tian, Charles Testa, Jeff G. Leid, Michael Valentine, Nicole V. Warrington, Andrew T. Koppisch, Emily K. Cope, David T. Fox, Kellan B. Finney, Suraj Dhungana, Paul D. Phillips
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95271 (2014)
PLoS ONE
PLoS ONE
Fosmidomycin is a time-dependent nanomolar inhibitor of methylerythritol phosphate (MEP) synthase, which is the enzyme that catalyzes the first committed step in the MEP pathway to isoprenoids. Importantly, fosmidomycin is one of only a few MEP pathw