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pro vyhledávání: '"Nicole Vüllings"'
Autor:
Tobias Troost, Ekaterina Seib, Alina Airich, Nicole Vüllings, Aleksandar Necakov, Stefano De Renzis, Thomas Klein
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background Ubiquitylation (ubi) of the intracellular domain of the Notch ligand Delta (Dl) by the E3 ligases Neuralized (Neur) and Mindbomb1 (Mib1) on lysines (Ks) is thought to be essential for the its signalling activity. Nevertheless, we
Externí odkaz:
https://doaj.org/article/9fca8440eb534bae9f46251419d5f760
Autor:
Konstantina Kalodimou, Margarita Stapountzi, Nicole Vüllings, Ekaterina Seib, Thomas Klein, Christos Delidakis
Publikováno v:
Cells, Vol 12, Iss 24, p 2833 (2023)
The execution of a Notch signal at the plasma membrane relies on the mechanical force exerted onto Notch by its ligand. It has been appreciated that the DSL ligands need to collaborate with a ubiquitin (Ub) ligase, either Neuralized or Mindbomb1, in
Externí odkaz:
https://doaj.org/article/bd7a264b81ec44f696af942a890b3ad9