Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nicole Ulmer"'
Autor:
Caterina Ruggeri, Hervé Broly, Moritz Wolf, Fabian Feidl, Massimo Morbidelli, Sebastian Vogg, Matevz Podobnik, Alessandro Butté, Nicole Ulmer, Ruben Wälchli, Jonathan Souquet
Publikováno v:
Biotechnology and Bioengineering. 117:1367-1380
Integrated continuous manufacturing is entering the biopharmaceutical industry. The main drivers range from improved economics, manufacturing flexibility, and more consistent product quality. However, studies on fully integrated production platforms
Publikováno v:
Biotechnology and Bioengineering. 117:662-672
Aggregates are amongst the most important product-related impurities to be removed during the downstream processing of antibodies due to their potential immunogenicity. Traditional operations use cation-exchange resins in bind-elute mode for their se
Publikováno v:
Current Opinion in Colloid & Interface Science. 31:86-91
Protein PEGylation plays an important role in the whole panel of reactions used for the modification and improvement of therapeutic proteins. The classic production process consists of a batch reactor followed by a purification unit. In this review,
Publikováno v:
Chemie Ingenieur Technik. 88:1598-1608
Over the past decades, the pharmaceutical industry has shown a continuous infatuation for therapeutic proteins. In order to constantly improve their efficacy, chemical reactions involving the conjugation of the therapeutic protein with various chemic
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1904
This chapter summarizes the most common chromatographic mAb and mAb fragment purification methods, starting by elucidating the relevant properties of the compounds and introducing the various chromatography modes that are available and useful for thi
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989577
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24cd3816a3fe73e4174883183b65f990
https://doi.org/10.1007/978-1-4939-8958-4_7
https://doi.org/10.1007/978-1-4939-8958-4_7
Publikováno v:
Biotechnology journal. 14(10)
Intensified processing and end-to-end integrated continuous manufacturing are increasingly being considered in bioprocessing as an alternative to the current batch-based technologies. Similar approaches can also be used at later stages of the product
Publikováno v:
Journal of chromatography. A. 1492
As typical for separation processes, single unit batch chromatography exhibits a trade-off between purity and yield. The twin-column MCSGP (multi-column countercurrent solvent gradient purification) process allows alleviating such trade-offs, particu
Publikováno v:
Biotechnology Journal. 14:1800732
The semicontinuous twin-column multicolumn countercurrent solvent gradient purification (MCSGP) process improves the trade-off between purity and yield encountered in traditional batch chromatography, while its complexity, in terms of hardware requir
Rare earth elements (REE) are widely used in industrial products, such as magnets, superconductors, and batteries. As the worldwide demand of REEs was increasing drastically during the past decade and the applications require very high purity materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb86147df5b2bfb8dc0b65e72d1b55
http://hdl.handle.net/11311/901955
http://hdl.handle.net/11311/901955