Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicole Teller"'
Autor:
Stefan Bräse, Sonja Thaler, Sylvia Vanderheiden, Jonathan P. Sleeman, Doris Marko, Bettina Göppert, Wilko Thiele, Melanie Rothley, Arno Dimmler, Verena Eschbach, Nicole Teller, Diana Plaumann, Bekir Bulat, Natascha Cremers, Anja Schmaus, Nicole Jung, Luca Quagliata
Publikováno v:
Carcinogenesis. 34:2804-2813
We have recently demonstrated that the anthocyanidin delphinidin (DEL), one of the most abundant dietary flavonoids, inhibits activation of ErbB and vascular endothelial growth factor receptor family members. These receptors play crucial roles in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb5e4c3c434d6c7b43a44cf8b248df6
https://doi.org/10.1093/carcin/bgt291
https://doi.org/10.1093/carcin/bgt291
Autor:
Thomas Hofmann, Veronika Somoza, Nicole Teller, Ute Boettler, Doris Marko, Katharina Sommerfeld, Gudrun Pahlke, Roman Lang, Nadine Volz
Publikováno v:
The Journal of Nutritional Biochemistry. 22:426-440
Oxidative cellular stress initiates Nrf2 translocation into the nucleus, thus inducing antioxidant response element (ARE)-mediated expression of Phase II enzymes involved in detoxification and antioxidant defence. We investigated whether coffee extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e876293a2f7c1bb29b02a7867ee9b4f8
https://doi.org/10.1016/j.jnutbio.2010.03.011
https://doi.org/10.1016/j.jnutbio.2010.03.011
Publikováno v:
Molecular Nutrition & Food Research. 53:1075-1083
Delphinidin has been reported to inhibit EGFR signalling. To determine whether other receptor tyrosine kinases (RTKs) are also influenced by delphinidin, we examined its ability to inhibit the kinase activity of EGFR, ErbB2, VEGFR-2, VEGFR-3 and IGF1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6ba40520d59f1de47ffb156fb6eab9
https://doi.org/10.1002/mnfr.200800524
https://doi.org/10.1002/mnfr.200800524
Autor:
David P. Berry, Andreas J. Gescher, Hong Cai, Sarah C. Thomasset, William P. Steward, Doris Marko, Nicole Teller
Publikováno v:
Cancer Chemotherapy and Pharmacology. 64:201-211
Anthocyanins, plant pigments in fruits and berries, have been shown to delay cancer development in rodent models of carcinogenesis, especially those of the colorectal tract. Anthocyanins and anthocyanidins, their aglycons, especially cyanidin and del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e9f10b62a7ebbbbf8e1f94e1bd187a
https://doi.org/10.1007/s00280-009-0976-y
https://doi.org/10.1007/s00280-009-0976-y
Publikováno v:
Molecular Nutrition & Food Research. 52:815-822
In the present study, delphinidin was found to suppress the phosphorylation of the epidermal growth factor receptor (EGFR) within human tumour cells (human colon carcinoma cell line (HT29), human vulva carcinoma cell line (A431)), albeit less effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2104fd6e8902ed4839ce0b183a8ebc6f
https://doi.org/10.1002/mnfr.200800026
https://doi.org/10.1002/mnfr.200800026
Autor:
Wolfgang Hümmer, Francis Raul, Volker Blust, Ute Boettler, Melanie Esselen, Elke Richling, Matthias Roth, Peter Schreier, Diana Fridrich, Nicole Teller, Helmut Dietrich, Frank Will, Doris Marko
Publikováno v:
Foodfunction. 4(5)
Complex polyphenol-rich extracts from apples are known to inhibit the activity of the epidermal growth factor receptor (EGFR) in vitro. The aim of the present study was to identify the bioactive constituents of the apple juice extract which contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0021ae8d8dbe94bf231fc78fc6636fa6
https://pubmed.ncbi.nlm.nih.gov/23403595
https://pubmed.ncbi.nlm.nih.gov/23403595
Autor:
Herbert Stiebitz, Ingo Lantz, Veronika Somoza, Nadine Volz, Lyn R. Griffiths, Roman Lang, Ute Boettler, Nicole Teller, Christoph Schwarz, Doris Marko, Gerhard Bytof, Tamara Bakuradze, Thomas Hofmann, Gerhard Eisenbrand, Larisa M. Haupt, Swantje Winkler
Publikováno v:
Journal of agricultural and food chemistry. 60(38)
This study investigated Nrf2-activating properties of a coffee blend combining raw coffee bean constituents with 5-O-caffeoylquinic acid (CGA) as a lead component with typical roasting products such as N-methylpyridinium (NMP). In cell culture (HT29)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0cdcf039522a66601fc5f13412f9ee
https://pubmed.ncbi.nlm.nih.gov/22946519
https://pubmed.ncbi.nlm.nih.gov/22946519
Autor:
Tamara Bakuradze, Larisa M. Haupt, Ingo Lantz, Ute Boettler, Gerhard Eisenbrand, Nadine Volz, Gerhard Bytof, Nicole Teller, Lyn R. Griffiths, Doris Marko
Publikováno v:
Molecular Biology Reports
The Nrf2/ARE pathway is a major cellular defense mechanism that prevents damage by reactive oxygen species through induction of antioxidative phase II enzymes. However, the activity of the Nrf2/ARE system is not uniform with variability in response p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0606b9c71bbccf6961cc0f65563d93
https://pubmed.ncbi.nlm.nih.gov/22314914
https://pubmed.ncbi.nlm.nih.gov/22314914
Autor:
Doris Marko, Melanie Hutter, Ute Boettler, S. Skrbek, Simone Bächler, Nicole Teller, Melanie Esselen, Corinna E. Rüfer
Publikováno v:
Journal of agricultural and food chemistry. 59(13)
In the present study, we addressed the question whether cyanidin-3-glucoside (C3G) or complex C3G-rich blackberry extracts affect human topoisomerases with special emphasis on the contribution of the potential degradation products phloroglucinol alde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3d88335c69799bf1dabbbec0569ec0
https://pubmed.ncbi.nlm.nih.gov/21599019
https://pubmed.ncbi.nlm.nih.gov/21599019
Autor:
Ingo Lantz, Nadine Volz, Herbert Stiebitz, Veronika Somoza, Ute Boettler, Gerhard Bytof, Roman Lang, Christine Kotyczka, Gudrun Pahlke, Doris Marko, Nicole Teller, Thomas Hofmann
Publikováno v:
University of Vienna-u:cris
Recently, the coffee constituents 5-O-caffeoylquinic acid (CGA) and N-methylpyridinium (NMP) were identified as inducers of the Nrf2/antioxidant-response element (ARE) detoxifying pathway under cell-culture condition. To study the impact of CGA and N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1573acca03f443b85aa0267e2e9746
https://pubmed.ncbi.nlm.nih.gov/21448860
https://pubmed.ncbi.nlm.nih.gov/21448860