Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicole Strätz"'
Autor:
Katja Quarch, Stefanie Ruhs, Claudia Grossmann, Michael Gekle, Conny Köhler, Alexander Nolze, Nicole Strätz
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 233(3)
Aim This study investigates the role of calcineurin for angiotensin II (AngII)-induced vascular remodelling with the help of a mouse model lacking the catalytic beta subunit of calcineurin (PPP3CB KO). Methods Wildtype (WT) and PPP3CB KO mice were tr
Autor:
Barbara Schreier, Julia Hupfeld, Danny Misiak, Maria Knyrim, Sigrid Mildenberger, Nicole Strätz, Katja Quarch, Stephanie Binas, Udo Kloeckner, Claudia Grossmann, Michael Gekle, Sindy Rabe
Publikováno v:
Cellular and Molecular Life Sciences
MicroRNAs (miRs) contribute to different aspects of cardiovascular pathology, among others cardiac hypertrophy and atrial fibrillation. The aim of our study was to evaluate the impact of miR-221/222 on cardiac electrical remodeling. Cardiac miR expre
Autor:
Katja Quarch, Mike Schutkowski, Stefanie Ruhs, Nicole Strätz, Claudia Grossmann, Michael Gekle, Antonia Masch
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
The pathogenesis of cardiovascular diseases is a multifunctional process in which the mineralocorticoid receptor (MR), a ligand-dependent transcription factor, is involved as proven by numerous clinical studies. The development of pathophysiological
Autor:
Kay Trenkmann, Katja Schumann, Barbara Schreier, Jens Keilwagen, Ivo Grosse, Stefanie Ruhs, Claudia Grossmann, Michael Gekle, Nicole Strätz, Sandra Meinel
Publikováno v:
Nucleic Acids Research
The mineralocorticoid receptor (MR) is a ligand-induced transcription factor belonging to the steroid receptor family and involved in water-electrolyte homeostasis, blood pressure regulation, inflammation and fibrosis in the renocardiovascular system
Autor:
Nicole Strätz, Stefanie Ruhs, Sindy Rabe, Kathleen Schlör, Sandra Meinel, Claudia Grossmann, Michael Gekle, Sigrid Mildenberger
Publikováno v:
Free Radical Biology and Medicine. 53:1088-1100
The mineralocorticoid receptor (MR) plays an important role in salt and water homeostasis and pathological tissue modifications, such as cardiovascular and renal fibrosis. Importantly, MR activation by aldosterone per se is not sufficient for the del
Autor:
Katja Schumann, Lisa Langenbruch, Stefanie Ruhs, Nicole Strätz, Sigrid Mildenberger, Claudia Grossmann, Michael Gekle
Publikováno v:
Chemistry & Biology. (6):742-751
SummaryThe mineralocorticoid receptor (MR), a member of the steroid receptor superfamily, regulates water-electrolyte balance and mediates pathophysiological effects in the renocardiovascular system. Previously, it was assumed that after binding aldo