Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Nicole Stolte"'
Autor:
Alexandre Laliberté, Caterina Prelli Bozzo, Christiane Stahl-Hennig, Victoria Hunszinger, Simone Joas, Ulrike Sauermann, Berit Roshani, Antonina Klippert, Maria Daskalaki, Kerstin Mätz-Rensing, Nicole Stolte-Leeb, Gregory K. Tharp, Dietmar Fuchs, Prachi Mehrotra Gupta, Guido Silvestri, Sydney A. Nelson, Laura Parodi, Luis Giavedoni, Steven E. Bosinger, Konstantin M.J. Sparrer, Frank Kirchhoff
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108351- (2023)
Summary: The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces cell-cycle arrest in cell culture. However, its impact in vivo is controversial. Her
Externí odkaz:
https://doaj.org/article/d97b01ec79264fde9d35d16bbbf8793a
Autor:
Simone Joas, Ulrike Sauermann, Berit Roshani, Antonina Klippert, Maria Daskalaki, Kerstin Mätz-Rensing, Nicole Stolte-Leeb, Anke Heigele, Gregory K. Tharp, Prachi Mehrotra Gupta, Sydney Nelson, Steven Bosinger, Laura Parodi, Luis Giavedoni, Guido Silvestri, Daniel Sauter, Christiane Stahl-Hennig, Frank Kirchhoff
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
Summary: The inability of Nef to downmodulate the CD3-T cell receptor (TCR) complex distinguishes HIV-1 from other primate lentiviruses and may contribute to its high virulence. However, the role of this Nef function in virus-mediated immune activati
Externí odkaz:
https://doaj.org/article/03906fd8cd7840c89119e99657af1d0a
Autor:
Artur Kaul, Martina Bleyer, Ulrike Sauermann, Maria Daskalaki, Berit Neumann, Christiane Stahl-Hennig, Frank Kirchhoff, Antonina Klippert, Nicole Stolte-Leeb
Publikováno v:
Primate Biology, Vol 3, Iss 2, Pp 65-75 (2016)
Despite combination antiretroviral therapy, high-grade malignant non-Hodgkin's lymphoma (NHL) is still one of the most frequently acquired immunodeficiency syndrome (AIDS)-defining disorders in the end stage of infection with human immunodeficiency v
Autor:
Sydney A. Nelson, Kerstin Mätz-Rensing, Christiane Stahl-Hennig, Simone Joas, Anke Heigele, Luis D. Giavedoni, Ulrike Sauermann, Daniel Sauter, Guido Silvestri, Antonina Klippert, Prachi Mehrotra Gupta, Berit Roshani, Frank Kirchhoff, Gregory K. Tharp, Laura M. Parodi, Maria Daskalaki, Steven E. Bosinger, Nicole Stolte-Leeb
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
Cell Reports, Vol 30, Iss 7, Pp 2261-2274.e7 (2020)
SUMMARY The inability of Nef to downmodulate the CD3-T cell receptor (TCR) complex distinguishes HIV-1 from other primate lentiviruses and may contribute to its high virulence. However, the role of this Nef function in virus-mediated immune activatio
Autor:
Antonia Radaelli, Nicole Stolte-Leeb, Katharina Raue, Klaus Überla, Carlo De Giuli Morghen, Brandon F. Keele, Massimiliano Bissa, Sieghart Sopper, Carlo Zanotto, Michael Krawczak, Matthias Tenbusch, Ulrike Sauermann, Christiane Stahl-Hennig
Publikováno v:
Journal of Virology. 91
An effective AIDS vaccine should elicit strong humoral and cellular immune responses while maintaining low levels of CD4 + T-cell activation to avoid the generation of target cells for viral infection. The present study investigated two prime-boost r
Autor:
Christiane Stahl-Hennig, Ali Gawanbacht, Antonina Klippert, Nicole Stolte-Leeb, Maria Daskalaki, Berit Neumann, Ulrike Sauermann, Frank Kirchhoff
Publikováno v:
Journal of Medical Primatology. 44:253-262
Background T-follicular helper (TFH) cells are an important population in lymph nodes (LNs) contributing to the generation of highly specific B cells. For SIV studies in rhesus macaques (RM), analysis of LN is necessary, but restricted due to invasiv
Autor:
Ulrike, Sauermann, Antonia, Radaelli, Nicole, Stolte-Leeb, Katharina, Raue, Massimiliano, Bissa, Carlo, Zanotto, Michael, Krawczak, Matthias, Tenbusch, Klaus, Überla, Brandon F, Keele, Carlo, De Giuli Morghen, Sieghart, Sopper, Christiane, Stahl-Hennig
Publikováno v:
Journal of virology. 91(23)
An effective AIDS vaccine should elicit strong humoral and cellular immune responses while maintaining low levels of CD4+ T-cell activation to avoid the generation of target cells for viral infection. The present study investigated two prime-boost re
Autor:
Maria Daskalaki, Li Lin Gan, Nicole Stolte-Leeb, Tingchuan Shi, Christiane Stahl-Hennig, Berit Neumann, Antonina Klippert
Publikováno v:
Journal of medical primatology. 45(3)
Background Common marmosets are extensively used in immunological and pharmacological research, and the usage of methods such as flow cytometry gain increasing importance. Methods Using multicolor flow cytometry cross-reactivity of monoclonal antibod
Autor:
Tina Schultheiss, Sophia G. Antimisiaris, Richard Storer, Roberta Loddo, Christophe Parsy, Nicole Stolte-Leeb, Ulrike Sauermann, Paolo La Colla, Christiane Stahl-Hennig, Monika Franz, Spyridon Mourtas
Publikováno v:
AIDS Research and Human Retroviruses. 27:933-943
The availability of an effective vaginal microbicide would be a major step toward containment of HIV transmission as well as allowing women self-protection against HIV infection. Here we evaluated the efficacy of vaginal application of the potent non
Publikováno v:
Journal of Medical Primatology. 40:41-51
Background Rhesus monkeys play a central role in model studies on human infectious diseases, and often mucosal organs are affected by these pathogens, e.g. HIV. However, a comparative investigation into lymphocyte composition from different mucosal t