Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nicole Shuang Yu Chia"'
Autor:
Adeline Su Lyn Ng, Yi Jayne Tan, Alisa Cui Wen Yong, Seyed Ehsan Saffari, Zhonghao Lu, Ebonne Yulin Ng, Samuel Yong Ern Ng, Nicole Shuang Yu Chia, Xinyi Choi, Dede Heng, Shermyn Neo, Zheyu Xu, Nicole Chwee Har Keong, Kay Yaw Tay, Wing Lok Au, Louis Chew Seng Tan, Eng-King Tan
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background The main motor subtypes of Parkinson’s disease (PD) include tremor-dominant (TD) and postural instability gait disorder (PIGD), with varying disease course that warrant the development of biomarkers capable of predicting progres
Externí odkaz:
https://doaj.org/article/6726f7a3e61441c6af07683d1088d811
Microstructure of Brain Nuclei in Early Parkinson’s Disease: Longitudinal Diffusion Kurtosis Imaging
Autor:
Thomas Welton, Septian Hartono, Yao-Chia Shih, Weiling Lee, Pik Hsien Chai, Say Lee Chong, Samuel Yong Ern Ng, Nicole Shuang Yu Chia, Xinyi Choi, Dede Liana Heng, Eng-King Tan, Louis C.S. Tan, Ling-Ling Chan
Publikováno v:
Journal of Parkinson's Disease. 13:233-242
Background: Diffusion kurtosis imaging provides in vivo measurement of microstructural tissue characteristics and could help guide management of Parkinson’s disease. Objective: To investigate longitudinal diffusion kurtosis imaging changes on magne
Autor:
Samuel Yong-Ern Ng, Nicole Shuang-Yu Chia, Mirza Masoom Abbas, Ehsan Seyed Saffari, Xinyi Choi, Dede Liana Heng, Zheyu Xu, Kay-Yaw Tay, Wing-Lok Au, Eng-King Tan, Louis Chew-Seng Tan
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Objective: In a prospective study, we investigated the association between physical activity and various motor, non-motor outcomes, and quality of life in early Parkinson's disease (PD) participants in the PD Longitudinal Singapore Study.Background:
Externí odkaz:
https://doaj.org/article/23eaf54f05d74cc3a1c145c871dd9616
Autor:
Leon Qi Rong Ooi, Ming-Ching Wen, Samuel Yong-Ern Ng, Nicole Shuang-Yu Chia, Isabel Hui Min Chew, Weiling Lee, Zheyu Xu, Septian Hartono, Eng King Tan, Ling Ling Chan, Louis Chew-Seng Tan
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Externí odkaz:
https://doaj.org/article/14768bfdeba74e6ba79ab55553121798
Autor:
Leon Qi Rong Ooi, Ming-Ching Wen, Samuel Yong-Ern Ng, Nicole Shuang-Yu Chia, Isabel Hui Min Chew, Weiling Lee, Zheyu Xu, Septian Hartono, Eng King Tan, Ling Ling Chan, Louis Chew-Seng Tan
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Background and ObjectivesThe underlying neuropathology of excessive daytime sleepiness (EDS) remains elusive in Parkinson’s disease (PD). We aim to investigate neural network changes that underlie EDS in PD.MethodsEarly PD patients comprising eight
Externí odkaz:
https://doaj.org/article/19be4fdd93c2486596571b97ed0e0892
Publikováno v:
IEEE Transactions on Biomedical Engineering. 69:2256-2267
Parkinson's disease (PD) is a chronic, non-reversible neurodegenerative disorder, and freezing of gait (FOG) is one of the most disabling symptoms in PD as it is often the leading cause of falls and injuries that drastically reduces patients' quality
Autor:
Matthew Rui En, Koh, Cong Yang, Chua, Samuel Yong-Ern, Ng, Nicole Shuang-Yu, Chia, Seyed Ehsan, Saffari, Regina Yu-Ying, Chen, Xinyi, Choi, Dede Liana, Heng, Shermyn Xiumin, Neo, Kay Yaw, Tay, Wing Lok, Au, Eng-King, Tan, Louis Chew-Seng, Tan, Zheyu, Xu
Publikováno v:
Frontiers in Neurology. 13
BackgroundSleep disorders are common in Parkinson's disease (PD). However, the longitudinal relationship between sleep quality and the other non-motor symptoms of PD has not been well characterized, especially in early PD.ObjectiveTo explore the valu
Autor:
Seyed Ehsan Saffari, Ming-Ching Wen, Dede Liana Heng, Cong Yang Chua, Zheyu Xu, Wing Lok Au, Shermyn Xiumin Neo, Regina Yu-Ying Chen, Nicole Shuang-Yu Chia, Matthew Rui En Koh, Eng-King Tan, Kay Yaw Tay, Louis C.S. Tan, Samuel Yong-Ern Ng, Xinyi Choi
Publikováno v:
Parkinsonism & Related Disorders. 82:24-28
Introduction Subjective cognitive complaints (SCC) and affective symptoms are highly prevalent in Parkinson's Disease (PD). In early PD, SCC prevalence and its affective correlates, using recommended Movement Disorders Society (MDS) Level II Criteria
Autor:
Reudi J W Chan, Wing Lok Au, Adeline S.L. Ng, Joel Y. J. Foo, Nicole Shuang-Yu Chia, Alisa C.W. Yong, Kay-Yaw Tay, Sherwin J. U. Agustin, Sherilyn Seah, Louis C.S. Tan, Shermyn Neo
Publikováno v:
Cell and Tissue Banking. 21:265-277
Brain donations are imperative for research; understanding possible barriers to entry is required to improve brain donation rates. While a few surveys have studied attitudes towards brain banking in patients with neurodegenerative disorders, none hav
Autor:
Kay Yaw Tay, Nicole C Keong, Ebonne Yulin Ng, Zheyu Xu, Samuel Yong-Ern Ng, Wing Lok Au, Eng-King Tan, Yi Jayne Tan, Nicole Shuang-Yu Chia, Fiona Setiawan, Adeline Su Lyn Ng, Louis C.S. Tan, Zhonghao Lu
Publikováno v:
Aging (Albany NY)
Parkinson’s disease (PD) is characterized by Lewy bodies containing α-synuclein and ubiquitin aggregates, their co-occurrence possibly linked to a failure of the ubiquitin proteasome system. Ubiquitin C-terminal hydrolase L1 (UCHL1) plays an impor