In vitro activity of the first-in-class triazaacenaphthylene gepotidacin alone and in combination with doxycycline against drug-resistant and -susceptible Mycoplasma genitalium

Autor: Jørgen Skov Jensen, Christina Nørgaard, Nicole Scangarella-Oman, Magnus Unemo

Publikováno v: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1388-1392 (2020)

ABSTRACTMycoplasma genitalium has developed resistance to first-line azithromycin and second-line moxifloxacin. Third-line pristinamycin is only 75% effective. Gepotidacin, a novel triazaacenaphthylene topoisomerase II inhibitor, blocks bacterial DNA

Externí odkaz: https://doaj.org/article/743db303a09b40bcab2aab37a284a8d9

Antimicrobial Activity of Gepotidacin Tested against Escherichia coli and Staphylococcus saprophyticus Isolates Causing Urinary Tract Infections in Medical Centers Worldwide (2019 to 2020)

Autor: S. J. Ryan Arends, Deborah Butler, Nicole Scangarella-Oman, Mariana Castanheira, Rodrigo E. Mendes

Publikováno v: Antimicrobial Agents and Chemotherapy. 67

The in vitro activities of gepotidacin and comparator agents against 3,560 Escherichia coli and 344 Staphylococcus saprophyticus collected from female (81.1%) and male (18.9%) patients with urinary tract infections (UTIs) in a global prospective surv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::030c260c4bb9dbfe2c6162c1c5871067
https://doi.org/10.1128/aac.01525-22

Molecular Epidemiology of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates from Global Clinical Trials

Autor: Stacey L. Walsh, Monique Twynholm, Elizabeth Thomas, F. Patrick O'Hara, Julie A. Becker, Stephanie Van Horn, Heather Amrine-Madsen, Richard V. Goering, Ribhi M. Shawar, Nicole Scangarella, Marybeth Dalessandro, Linda A. Miller, Joshua West

Publikováno v: Journal of Clinical Microbiology. 46:2842-2847

Determining the genetic characteristics of Staphylococcus aureus is important for better understanding of the global and dynamic epidemiology of this organism as we witness the emergence and spread of virulent and antibiotic-resistant clones. We geno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc521a01020b9996f54cbd1abe25112
https://doi.org/10.1128/jcm.00521-08

Contents Vol. 215, 2007

Autor: M.R. Kamoun, Sven Klebs, P. Wolkenstein, S. Mastroeni, Laura Delaney, Sam Salek, B. Zouari, Liang Deng, Krishan Singh, Torsten Zuberbier, Iva Propperova, Lucie Heinzerling, D. Nassar, Jean-Hilaire Saurat, Nicole Scangarella, Monique Twynholm, Martine Chivot, Arnold P. Oranje, B. Cribier, Luigi Naldi, Salvatore Domenico Infusino, R. Zermani, Marco Ardigò, Ashfaq A. Marghoob, Claire Beylot, Steven F. Morris, Hongqing Tian, B. Fazaa, Noreen M. Walsh, H Pawin, D. Abeni, Rosy Tambasco, Fernando Rizzello, Philip Spencer, Damiano Abeni, F. Zeglaoui, Mala Bhalla, S. Tabolli, Maria Rita Nasca, Thomas Bieber, J.P. Hugot, Paolo Gionchetti, Jean Revuz, Gürkan Kaya, Changyuan Wang, Michel Faure, C. Morselli, Matthias Bräutigam, Tamar Nijsten, Francesca Sampogna, Beatrice Passarini, Massimo Campieri, Brigitte Dréno, Richard G. Langley, Satoshi Itami, Robert S. Stern, E.J.F. Franssen, Christine Labrèze, Ribhi Shawar, Alaw Roberts, Maria C. Garzon, Furen Zhang, F. Sampogna, Alon Scope, Takeshi Nakajima, K. Vos, S. Ben Jilani, A.M.A. Prins, I. Zaraa, Melissa Gill, Uwe Schauer, Xiaoxiao Yan, J. Revuz, Rocco De Pasquale, Olivier Chosidow, Christopher Gallant, C. Di Pietro, C. Fortes, Giuseppe Micali, Shigeki Inui, Jonathon Zieff, Elisa Varotti, Gurvinder P. Thami, Ashley E. Sutherland, Beth A. Drolet, M. Maalej, Deke Jiang, Long Yu, Gail Todd, Sarvajnamurthy Sacchidanand, Andrew Yule Finlay, Elena Barbieri, Florence Poli

Publikováno v: Dermatology. 215:377-379

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ae28b86446a04469f83de0d61167956
https://doi.org/10.1159/000110000

Efficacy and safety of retapamulin ointment as treatment of impetigo:randomized double-blind multicentre placebo-controlled trial

Autor: Nicole Scangarella, Sander Koning, Arnold P. Oranje, J.C. van der Wouden, K P Singh, Olivier Chosidow, Monique Twynholm

Publikováno v: Koning, S, van der Wouden, J C, Chosidow, O, Twynholm, M, Singh, K P, Scangarella, N & Oranje, A P 2008, ' Efficacy and safety of retapamulin ointment as treatment of impetigo : randomized double-blind multicentre placebo-controlled trial ', British Journal of Dermatology, vol. 158, no. 5, pp. 1077-82 . https://doi.org/10.1111/j.1365-2133.2008.08485.x
British Journal of Dermatology, 158(5), 1077-82. Wiley-Blackwell
British Journal of Dermatology, 158(5), 1077-1082. Wiley-Blackwell Publishing Ltd

BACKGROUND: Impetigo is a common skin infection, primarily caused by Staphylococcus aureus and mainly occurring in children. It is usually treated topically with antibiotics to achieve a quick cure and prevent spread of the infection. Worldwide, resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64910f442f14130f2cb2ad09ec7954d3
https://research.vumc.nl/en/publications/24ccf200-f5e7-4f8a-96e8-0ea2cf5a41d9