Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole S. Yeo-Teh"'
Autor:
Joanna Achinger-Kawecka, Fatima Valdes-Mora, Phuc-Loi Luu, Katherine A. Giles, C. Elizabeth Caldon, Wenjia Qu, Shalima Nair, Sebastian Soto, Warwick J. Locke, Nicole S. Yeo-Teh, Cathryn M. Gould, Qian Du, Grady C. Smith, Irene R. Ramos, Kristine F. Fernandez, Dave S. Hoon, Julia M. W. Gee, Clare Stirzaker, Susan J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Endocrine therapy resistance occurs often in estrogen receptor positive (ER+) breast cancer. Here, the authors find that 3D epigenome remodelling at ER-bound enhancer-promoter interactions is a key mechanism underlying endocrine resistance.
Externí odkaz:
https://doaj.org/article/fa0958eacf7f42d19237b40a66d1a2d1
Autor:
Fátima Valdés-Mora, Cathryn M. Gould, Yolanda Colino-Sanguino, Wenjia Qu, Jenny Z. Song, Kylie M. Taylor, Fabian A. Buske, Aaron L. Statham, Shalima S. Nair, Nicola J. Armstrong, James G. Kench, Kenneth M. L. Lee, Lisa G. Horvath, Minru Qiu, Alexei Ilinykh, Nicole S. Yeo-Teh, David Gallego-Ortega, Clare Stirzaker, Susan J. Clark
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Acetylation of the histone variant H2A.Z at gene promoters is associated with oncogene activation; however, it is unclear if such modification has a role in regulating the function of enhancers. Here the authors show that acetylated H2A.Z is redistri
Externí odkaz:
https://doaj.org/article/d2ff8d2d6d19424694b455f94d09d58c
Autor:
Katherine A. Giles, Fatima Valdes-Mora, C. Elizabeth Caldon, Kristine F Fernandez, Shalima S. Nair, Qian Du, Sebastian Soto, Grady C. Smith, Phuc-Loi Luu, Warwick J. Locke, Susan J. Clark, Joanna Achinger-Kawecka, Nicole S. Yeo-Teh, Clare Stirzaker, Wenjia Qu, Cathryn M. Gould, Dave S.B. Hoon, Julia Margaret Wendy Gee, Irene Ramos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Endocrine therapy resistance frequently develops in estrogen receptor positive (ER+) breast cancer, but the underlying molecular mechanisms are largely unknown. Here, we show that 3-dimensional (3D) chromatin interactions both within and between topo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c89f1accd432814abdeea1ce1d88523
Autor:
Yolanda Colino-Sanguino, Kylie M. Taylor, Lisa G. Horvath, Clare Stirzaker, Jenny Z. Song, Cathryn M. Gould, Wenjia Qu, Shalima S. Nair, James G. Kench, Nicola J. Armstrong, Fabian A. Buske, Nicole S. Yeo-Teh, Minru Qiu, Aaron L. Statham, David Gallego-Ortega, Fatima Valdes-Mora, Alexei Ilinykh, Susan J. Clark, Kenneth Lee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications
Acetylation of the histone variant H2A.Z (H2A.Zac) occurs at active promoters and is associated with oncogene activation in prostate cancer, but its role in enhancer function is still poorly understood. Here we show that H2A.Zac containing nucleosome