Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicole S. Nicholas"'
Autor:
Nur Fariesha Md Hashim, Nicole S. Nicholas, Anna E. Dart, Serafim Kiriakidis, Ewa Paleolog, Claire M. Wells
Publikováno v:
Open Biology, Vol 3, Iss 6 (2013)
During tumour progression, oxygen tension in the microenvironment surrounding tumour cells is reduced, resulting in hypoxia. It is well established that cancer cells resist the negative effects of hypoxia by inducing angiogenesis predominantly via th
Externí odkaz:
https://doaj.org/article/539648b63a2846f9871c1173a4866663
Publikováno v:
Nicholas, N, Pipili, A, Lesjak, M S & Wells, C M 2017, ' Differential role for PAK1 and PAK4 during the invadopodia lifecycle ', Small GTPases, pp. 1-7 . https://doi.org/10.1080/21541248.2017.1295830
PAK1 and PAK4 are members of the p-21 activated kinase family of serine/threonine kinases. PAK1 has previously been implicated in both the formation and disassembly of invasive cell protrusions, termed invadopodia. We recently reported a novel role f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935159c38530d01f9fe233309d09de80
https://doi.org/10.1080/21541248.2017.1295830
https://doi.org/10.1080/21541248.2017.1295830
Autor:
Anna E. Dart, Claire M. Wells, Ewa M. Paleolog, Serafim Kiriakidis, Nicole S. Nicholas, Nur Fariesha Md Hashim
Publikováno v:
Open Biology, Vol 3, Iss 6 (2013)
Open Biology
Open Biology
During tumour progression, oxygen tension in the microenvironment surrounding tumour cells is reduced, resulting in hypoxia. It is well established that cancer cells resist the negative effects of hypoxia by inducing angiogenesis predominantly via th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9bcacdccbca4f2949abc651460dd60c
https://doi.org/10.1098/rsob.120159
https://doi.org/10.1098/rsob.120159
Publikováno v:
Biochimica et biophysica acta. 1863(3)
Immune checkpoint blockade antibodies and immunomodulatory drugs can unleash anti-tumor T cell immunity and mediate durable cancer regressions. However, only a fraction of patients currently respond to immunotherapy. Lymphoid malignancies are known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773cc1fccf7d3be80ddea15830789c00
https://pubmed.ncbi.nlm.nih.gov/26554850
https://pubmed.ncbi.nlm.nih.gov/26554850
Autor:
Simon Ameer-Beg, Penny E. Morton, Richard Walker, Simao Coelho, Viviane Devauges, Simon P. Poland, Klaus Suhling, Madeline Parsons, David Tyndall, Robert Henderson, Nikola Krstajić, Nicole S. Nicholas, Justin Richardson, Claire M. Wells, David Day-Uei Li
Publikováno v:
Optics letters. 39(20)
Imaging the spatiotemporal interaction of proteins in vivo is essential to understanding the complexities of biological systems. The highest accuracy monitoring of protein–protein interactions is achieved using Forster resonance energy transfer (FR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e84faddfad7ca72f37e9d46db0287c
https://pubmed.ncbi.nlm.nih.gov/25361143
https://pubmed.ncbi.nlm.nih.gov/25361143
Publikováno v:
International review of cell and molecular biology. 309
The p-21-activated kinases (PAKs) are downstream effectors of Rho GTPases Rac and Cdc42. The PAK family consists of six members which are segregated into two subgroups (Group I and Group II) based on sequence homology. Group I PAKs (PAK1-3) are the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d1bbcae85913116ddfa83317ee88ee5
https://pubmed.ncbi.nlm.nih.gov/24529727
https://pubmed.ncbi.nlm.nih.gov/24529727
The p-21-activated kinases (PAKs) are downstream effectors of Rho GTPases Rac and Cdc42. The PAK family consists of six members which are segregated into two subgroups (Group I and Group II) based on sequence homology. Group I PAKs (PAK1-3) are the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d52b8c267f1de6dfabba787e0219d3f6
https://doi.org/10.1016/b978-0-12-800255-1.00007-7
https://doi.org/10.1016/b978-0-12-800255-1.00007-7
Autor:
Lesley-Ann Sutton, Rose-Marie Amini, Richard Rosenquist, Stephen Devereux, Nicole S. Nicholas, Benedetta Apollonio, Piers E.M. Patten, Shireen Kassam, Jon Salisbury, Alan G. Ramsay
Publikováno v:
Blood. 126:1474-1474
There is a clinical need to identify novel treatments for relapsed/refractory DLBCL. Cancer cells engage in novel associations with stromal and immune cells in the TME that provide crucial contributions to disease progression, immune evasion and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e5a06b0264464c7f22b3fd692d27c3
https://doi.org/10.1182/blood.v126.23.1474.1474
https://doi.org/10.1182/blood.v126.23.1474.1474