Incidence and prevalence of primary biliary cholangitis in the Netherlands – A nationwide cohort study

Autor: Rozanne C. de Veer, Maria C.B. van Hooff, Ellen Werner, Ulrich Beuers, Joost P.H. Drenth, Frans J.C. Cuperus, Bart van Hoek, Bart J. Veldt, Michael Klemt-Kropp, Suzanne van Meer, Robert C. Verdonk, Hajo J. Flink, Jan Maarten Vrolijk, Tom J.G. Gevers, Cyriel Y. Ponsioen, Martijn J. ter Borg, Khalida Soufidi, Femke Boersma, Hendrik J.M. de Jonge, Frank H.J. Wolfhagen, L.C. Baak, Susanne L. Onderwater, Jeroen D. van Bergeijk, Paul G. van Putten, Gijs J. de Bruin, Rob P.R. Adang, Maria N. Aparicio-Pages, Wink de Boer, Frank ter Borg, Hanneke van Soest, Harry L.A. Janssen, Bettina E. Hansen, Nicole S. Erler, Adriaan J. van der Meer, Sunje Abraham, Huseyin Aktas, Yasser A. Alderlieste, L. (Bert) C. Baak, Martine A.M.C. Baven-Pronk, A. (Sander) van der Beek, Frank C. Bekkering, Menno Beukema, Kirsten Boonstra, Pieter C.J. ter Borg, Paul J. Bus, Djuna L. Cahen, Marcel Cazemier, Lisette J.H. van Dam, Maaike J. Denters, Ludger S.M. Epping, Philip W. Friederich, Nicole F.M. van Gerven, Sven J. van den Hazel, Maria C. van Hooff, Daphne M. Hotho, Matthias C. Jurgens, J.(Netty) van Kemenade, Marjo J. Kerbert-Dreteler, Ingrid C.A.W. Konings, Sander de Kort, Edith M.M. Kuiper, Johan P.H. Kuyvenhoven, Leendert H. Oterdoom, Janne E. van Rooij, Robert Roomer, Johannes Schmidt-Böhmer, Stephan Schmittgens, Tim C.M.A. Schreuder, Jerome Sint Nicolaas, Stephan H.C. van Stiphout, Hans H.K. Thio, Merel M. Tielemans, Sigrid Vandebosch, J. Marleen de Vree, Elsemieke de Vries, Anne Vrieze, Laurens A. van der Waaij, Ulrike de Wit

Publikováno v: JHEP Reports, Vol 6, Iss 8, Pp 101132- (2024)

Background & Aims: Although primary biliary cholangitis (PBC) is considered a rare disorder, accurate determination of its incidence and prevalence remains challenging due to limited comprehensive population-based registries. We aimed to assess the i

Externí odkaz: https://doaj.org/article/b78f3031c746431b9a47676360ed92d8

Modifying Tacrolimus-related Toxicity After Liver Transplantation Comparing Life Cycle Pharma Tacrolimus Versus Extended-released Tacrolimus: A Multicenter, Randomized Controlled Trial

Autor: Midas B. Mulder, PharmD, Bart van Hoek, MD, PhD, Wojtek G. Polak, MD, PhD, Ian P.J. Alwayn, MD, PhD, Brenda C.M. de Winter, PharmD, PhD, Sarwa Darwish Murad, MD, PhD, Elke Verhey-Hart, BSc, Lara Elshove, MSc, Nicole S. Erler, Dipl-Stat, PhD, Dennis A. Hesselink, MD, PhD, Caroline M. den Hoed, MD, PhD, Herold J. Metselaar, MD, PhD

Publikováno v: Transplantation Direct, Vol 10, Iss 4, p e1612 (2024)

Background. The aim of this open-label, multicenter, randomized controlled study was to investigate whether the life cycle pharma (LCP)-tacrolimus compared with the extended-release (ER)-tacrolimus formulation results in a difference in the prevalenc

Externí odkaz: https://doaj.org/article/e000db20ac504b629c8bfe70cc940d02

Correction: A digital intake tool to avert outpatient visits in a FIT-based colorectal cancer screening population: study protocol of a multicentre, prospective non-randomized trial - the DIT-trial

Autor: Fleur E. Marijnissen, Pieter J. F. de Jonge, Nicole S. Erler, Sohal Y. Ismail, Iris Lansdorp-Vogelaar, Manon C. W. Spaander

Publikováno v: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/13558935cebd4023b9d97b661459de97

Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-neegative chronic hepatitis B: A multicentre cohort study

Autor: Milan J. Sonneveld, Shao-Ming Chiu, Jun Yong Park, Sylvia M. Brakenhoff, Apichat Kaewdech, Wai-Kay Seto, Yasuhito Tanaka, Ivana Carey, Margarita Papatheodoridi, Piero Colombatto, Florian van Bömmel, Thomas Berg, Fabien Zoulim, Sang Hoon Ahn, George N. Dalekos, Nicole S. Erler, Maurizia Brunetto, Heiner Wedemeyer, Markus Cornberg, Man-Fung Yuen, Kosh Agarwal, Andre Boonstra, Maria Buti, Teerha Piratvisuth, George Papatheodoridis, Chien-Hung Chen, Benjamin Maasoumy

Publikováno v: JHEP Reports, Vol 5, Iss 8, Pp 100790- (2023)

Background & Aims: Pretreatment predictors of finite nucleo(s)tide analogue (NUC) therapy remain elusive. We studied the association between pretreatment HBV DNA levels and outcomes after therapy cessation. Methods: Patients with chronic hepatitis B

Externí odkaz: https://doaj.org/article/ed567dc91f3c4d328c67f9acb5bbb743

JointAI: Joint Analysis and Imputation of Incomplete Data in R

Autor: Nicole S. Erler, Dimitris Rizopoulos, Emmanuel M. E. H. Lesaffre

Publikováno v: Journal of Statistical Software, Vol 100, Pp 1-56 (2021)

Missing data occur in many types of studies and typically complicate the analysis. Multiple imputation, either using joint modeling or the more flexible fully conditional specification approach, are popular and work well in standard settings. In sett

Externí odkaz: https://doaj.org/article/24ea8f5c04a845a89a969fd94506f21b