Výsledky vyhledávání - "Nicole Rojas-Colonelli"

A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination

Autor: Camila Flores, Felipe Gálvez-Cancino, Cesar Oyarce, Manuel Varas-Godoy, Paola Murgas, Sebastián Cruz-Gómez, Nicole Rojas-Colonelli, Daniela Sauma, Alvaro Lladser, Jonathan A. Roco

Publikováno v: Vaccine. 35:4148-4154

DNA vaccination is an attractive approach to elicit tumor-specific cytotoxic CD8+ T lymphocytes (CTL), which can mediate protective immunity against tumors. To initiate CTL responses, antigen-encoding plasmids employed for DNA vaccination need to act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5d88cff41def1d9f53902fe5970d30
https://doi.org/10.1016/j.vaccine.2017.06.041

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Blocking of p38 and transforming growth factor β receptor pathways impairs the ability of tolerogenic dendritic cells to suppress murine arthritis

Autor: María Carmen Molina, Octavio Aravena, Corina Peña, David Gárate, Carolina H. Ribeiro, Diego Catalán, Nicole Rojas-Colonelli, Paula Abello, Lorena Salazar, Barbara Pesce, Paulina A García-González, Juan Carlos Aguillón

Publikováno v: ARTHRITIS AND RHEUMATISM
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Objective Dendritic cells (DCs) modulated with lipopolysaccharide (LPS) are able to reduce inflammation when therapeutically administered into mice with collagen-induced arthritis (CIA). The aim of this study was to uncover the mechanisms that define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35a33afe4a8c11a183b321d4217b477
https://doi.org/10.1002/art.37702

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Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells

Autor: Paula Abello, Juan Carlos Aguillón, René E. M. Toes, Octavio Aravena, Lorena Salazar, Barbara Pesce, Diego Catalán, Miguel Cuchacovich, Nicole Rojas-Colonelli, María Carmen Molina, Carlos González, Flavio Salazar-Onfray, Adam Aguirre, Mario Delgado, Juan Contreras-Levicoy, Raquel Cepeda, Roberto Zúñiga, Alejandro Escobar

Publikováno v: ANNALS OF THE RHEUMATIC DISEASES
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Background: The use of regulatory or immature dendritic cells (DCs) as tools for modulating experimental rheumatoid arthritis is very recent. Tumour necrosis factor (TNF)-stimulated DCs have been shown to restore tolerance in experimental autoimmune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662b03ffd1abc5051271aafb71b24955
https://doi.org/10.1136/ard.2007.072199

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NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses

Autor: Maarten A. Ligtenberg, Rolf Kiessling, Nicole Rojas-Colonelli, Alvaro Lladser

Publikováno v: HUMAN VACCINES & IMMUNOTHERAPEUTICS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

DNA vaccines have been shown to elicit tumor-protective cytotoxic T lymphocyte (CTL) immunity in preclinical models, but have shown limited efficacy in cancer patients. Plasmids used for DNA vaccines can stimulate several innate immune receptors, tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33dabeb68ec82680ab0af286cfe507fc
https://europepmc.org/articles/PMC3906403/

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Harnessing dna-induced immune responses for improving cancer vaccines

Autor: Maarten A. Ligtenberg, Alvaro Lladser, Nicole Rojas-Colonelli, Jonathan A. Roco, Andrés A. Herrada, Paula Gonzalez-Figueroa, Cesar Oyarce

Publikováno v: HUMAN VACCINES & IMMUNOTHERAPEUTICS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

DNA vaccines have emerged as an attractive strategy to promote protective cellular and humoral immunity against the encoded antigen. DNA vaccines are easy to generate, inexpensive to produce and purify at large-scale, highly stable and safe. In addit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4bee9927b8fd3fdfc998703942a9fd

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Dexamethasone Pretreatment Followed by an Inoculation of Short-term Lipopolysaccharide-stimulated Dendritic Cells Improves the Response of Murine Collagen-induced Arthritis

Autor: M.I. Peña, Juan Carlos Aguillón, Diego Catalán, David Gárate, Nicole Rojas-Colonelli, Octavio Aravena

Publikováno v: CLINICAL IMMUNOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888b9dbb3faaa6a2170fa18b303ca3c7
https://doi.org/10.1016/j.clim.2010.03.307

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