Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicole Reich"'
Autor:
Michael P. Manns, Brigitte Schlegelberger, Florian Kühnel, Maria Sandbothe, Stephanie Roessler, Britta Skawran, Reena Buurman, Beate Vajen, Peter Schirmacher, Luisa Greiwe, Thomas Illig, Engin Gürlevik, Marlies Eilers, Alejandro Vaquero, Vera Schäffer, Nicole Reich, Thomas Longerich
Publikováno v:
Journal of Hepatology. 66:1012-1021
Background & Aims Modulation of microRNA expression is a potential treatment for hepatocellular carcinoma (HCC). Therefore, the epigenetically regulated microRNA-449 family (miR-449a, miR-449b, miR-449c) was characterized with regards to its function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383505fe0eb9f63fb0e6c1fc1974ac3d
https://doi.org/10.1016/j.jhep.2017.01.004
https://doi.org/10.1016/j.jhep.2017.01.004
Autor:
Klemens Rottner, Helma Tatge, Alexandra Olling, Ralf Gerhard, Sebastian Goy, Nicole Reich, Alexi K. Alekov, Lara-Antonia Beer, Michel Tenspolde
Publikováno v:
Cellular microbiology
Toxin A and Toxin B (TcdA/TcdB) are large glucosyltransferases produced by Clostridium difficile. TcdB but not TcdA induces reactive oxygen species-mediated early cell death (ECD) when applied at high concentrations. We found that nonglucosylated Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5341f0352c79b247f71d804bd61d16
https://pubmed.ncbi.nlm.nih.gov/29904993
https://pubmed.ncbi.nlm.nih.gov/29904993
Autor:
Katrin Palumbo, Christian Beyer, Alfiya Akhmetshina, Pawel Zerr, Clara Dees, Michal Tomcik, Nicole Reich, Georg Schett, Jörg H W Distler, Mark P. Mattson, Angelika Horn, Oliver Distler, Michael Sticherling, Jochen Zwerina
Publikováno v:
Arthritis & Rheumatism. 63:1396-1404
OBJECTIVE: Tissue fibrosis caused by pathologic activation of fibroblasts with increased synthesis of extracellular matrix components is a major hallmark of systemic sclerosis (SSc). Notch signaling regulates tissue differentiation, and abnormal acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e6d3c83dc60b80499871397ad778f0
https://doi.org/10.1002/art.30254
https://doi.org/10.1002/art.30254
Autor:
Pawel Zerr, Matthias Engel, Jörg H W Distler, Sieglinde Marquart, Katrin Palumbo, Nicole Reich, Alfiya Akhmetshina, Georg Schett, Jochen Zwerina, Michal Tomcik, Angelika Horn, Clara Dees, Oliver Distler
Publikováno v:
Arthritis & Rheumatism. 62:3467-3476
Objective. Cannabinoids are derivates of the marijuana component 9 -tetrahydrocannabinol that exert their effects on mesenchymal cells and immune cells via CB1 and CB2 receptors. The aim of the present study was to evaluate the role of CB1 in systemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bafb20d56687336fdee16e3aae4393c
https://doi.org/10.1002/art.27642
https://doi.org/10.1002/art.27642
Autor:
Jörg H W Distler, Alfiya Akhmetshina, Georg Schett, Tatiana Nevskaya, Gabriella Szücs, Jürgen Beer, Johannes Gusinde, Nicole Reich, Dontscho Kerjaschki, Clara Dees, Katrin Palumbo, Oliver Distler, Matthias Englbrecht, Karin Zwerina, Jochen Zwerina
Publikováno v:
Arthritis & Rheumatism. 62:1513-1522
Objective Systemic sclerosis (SSc) is a connective tissue disease that is characterized by microvascular disease and tissue fibrosis. Progressive loss and irregular architecture of the small blood vessels are well characterized, but the potential inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5c24308a4729213c6b0784d1533582
https://doi.org/10.1002/art.27406
https://doi.org/10.1002/art.27406
Autor:
Maik Luu, Zeno Riester, Adrian Baldrich, Nicole Reichardt, Samantha Yuille, Alessandro Busetti, Matthias Klein, Anne Wempe, Hanna Leister, Hartmann Raifer, Felix Picard, Khalid Muhammad, Kim Ohl, Rossana Romero, Florence Fischer, Christian A. Bauer, Magdalena Huber, Thomas M. Gress, Matthias Lauth, Sophia Danhof, Tobias Bopp, Thomas Nerreter, Imke E. Mulder, Ulrich Steinhoff, Michael Hudecek, Alexander Visekruna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The activity of immune cells can be regulated by the microbiome. Here, the authors show that the fatty acids pentanoate and butyrate—normally released by the microbiome—increase the anti-tumour activity of cytotoxic T lymphocytes and chimeric ant
Externí odkaz:
https://doaj.org/article/b049d4b46e18405fa995dd666bce268c
Autor:
Brydon L. Bennett, Jörg H W Distler, Nicole Reich, Oliver Distler, Alfiya Akhmetshina, Christian Beyer, Pawel Zerr, Georg Schett, Clara Dees, Jérôme Avouac, Katrin Palumbo, Angelika Horn, Michal Tomcik, Veronika Lang, Weilin Xie
Publikováno v:
Annals of the rheumatic diseases. 71(5)
ObjectivesThe hallmark of systemic sclerosis (SSc) is the accumulation of extracellular matrix proteins by pathologically activated fibroblasts. This study analysed the antifibrotic effects of the selective c-Jun N-terminal kinase (JNK) inhibitor, CC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df06a56eed87df0e785d38967abeea39
https://pubmed.ncbi.nlm.nih.gov/22258492
https://pubmed.ncbi.nlm.nih.gov/22258492
Autor:
Oliver Distler, Clara Dees, Sonia C Schindler, Georges von Degenfeld, Nicole Reich, Alfiya Akhmetshina, Jörg H W Distler, Christian Beyer, Georg Schett, Claudia Hirth-Dietrich, Michal Tomcik, Peter Sandner
Background: Fibrosis and vascular disease are cardinal features of systemic sclerosis (SSc). Stimulators of soluble guanylate cyclase (sGC) are vasoactive drugs that are currently being evaluated in phase III clinical trials for pulmonary arterial hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f9cbcda06f484212c21a1d7bc3e8ae
https://doi.org/10.5167/uzh-63272
https://doi.org/10.5167/uzh-63272
Autor:
Britta Maurer, Nicole Reich, Astrid Juengel, Jörg Kriegsmann, Renate E Gay, Georg Schett, Beat A Michel, Steffen Gay, Jörg H W Distler, Oliver Distler
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases; Vol 71
Annals of the Rheumatic Diseases; Vol 71
Objective Systemic sclerosis-associated pulmonary arterial hypertension differs from idiopathic pulmonary arterial hypertension with respect to histopathology, treatment responses and survival. Medical progress on PAH is hampered by the lack of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe77697db3ae6260cc50b97e09a3bd5
https://doi.org/10.5167/uzh-62507
https://doi.org/10.5167/uzh-62507
Autor:
Clara Dees, Alfiya Akhmetshina, Pawel Zerr, Nicole Reich, Katrin Palumbo, Angelika Horn, Astrid Jüngel, Christian Beyer, Gerhard Krönke, Jochen Zwerina, Rudolf Reiter, Natalia Alenina, Luc Maroteaux, Steffen Gay, Georg Schett, Oliver Distler, Jörg H.W. Distler
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩
Journal of Experimental Medicine, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩
Journal of Experimental Medicine, Rockefeller University Press, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩
Journal of Experimental Medicine, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩
International audience; Vascular damage and platelet activation are associated with tissue remodeling in diseases such as systemic sclerosis, but the molecular mechanisms underlying this association have not been identified. In this study, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66353a90fa65da9eb97c7ff4915ff5ad
https://www.zora.uzh.ch/id/eprint/48127/
https://www.zora.uzh.ch/id/eprint/48127/