Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicole R. Parker"'
Autor:
Amanda L. Hudson, Nicole R. Parker, Peter Khong, Jonathon F. Parkinson, Trisha Dwight, Rowan J. Ikin, Ying Zhu, Jason Chen, Helen R. Wheeler, Viive M. Howell
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
While treatment with surgery, radiotherapy and/or chemotherapy may prolong life for patients with glioblastoma, recurrence is inevitable. What is still being discovered is how much these treatments and recurrence of disease affect the molecular profi
Externí odkaz:
https://doaj.org/article/c7812e4886db453789e8b0680dda9954
Autor:
Jonathon Parkinson, Nicole R. Parker, Helen Wheeler, Amanda Hudson, Ying Zhu, Peter Khong, Viive M. Howell, Rowan J. Ikin
Publikováno v:
Neuro-Oncology. 19:vi34-vi35
Glioblastoma, the most common and aggressive brain cancer in adults, has a very grim prognosis and a 5 year survival rate of less than 10%. While treatment with surgery, radiotherapy and/or chemotherapy may prolong life, progression is inevitable. Wh
Autor:
Amanda L. Hudson, Jason J. Chen, Viive M. Howell, Zhangkai Jason Cheng, Nicole R. Parker, Ying Zhu, Rowan J. Ikin, Peter Khong, Jonathon Parkinson, Fatemeh Vafaee, Trisha Dwight, Helen Wheeler
Publikováno v:
Scientific Reports
Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. Promoter methylation status of the DNA repair enzyme O6-methylguanine DNA methyltransferase (M
Autor:
Deborah J. Marsh, Robert C. Baxter, Kathleen Phillips, Ussha Pillai, Diana E. Benn, Graham Wilkins, Nicole R. Parker, Ross C. Smith
Publikováno v:
Biopreservation and biobanking. 12(6)
Broad or general consent given by cancer patients for their tissue, blood, and clinical information to be stored in institutional biorepositories is fundamental to enable future ethical translational cancer research. The decision to consent for bioba
Autor:
Zhangkai Jason Cheng, Nicole R. Parker, Rowan J. Ikin, Fatemeh Vafaee, Peter Khong, Amanda L. Hudson, Viive M. Howell, Jonathon Parkinson, Helen Wheeler
Publikováno v:
Cancer Research. 75:B39-B39
Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. DNA repair mechanisms are key elements involved in the response to temozolomide with epigeneti
Autor:
Anthony J. Gill, Jaswinder S. Samra, Robert P. Eckstein, David Goldstein, Millie Lui, Angela Chou, Diana E. Benn, Vivienne Tobias, Ricardo E. Vilain, Roderick J. Clifton-Bligh, Ross C. Smith, Jenny Ma Wyatt, Stan B. Sidhu, Mark Sywak, Loretta Sioson, Richard Jin, Celia Smith, Nicole R. Parker, Adele Clarkson, Bruce G. Robinson
Publikováno v:
The American journal of surgical pathology. 34(5)
The Carney triad (CT) is gastrointestinal stromal tumor (GIST), paraganglioma, and pulmonary chondroma. The GISTs of CT show different clinical, molecular, and morphologic features to usual adult GISTs but are similar to the majority of pediatric GIS
Autor:
Alain Vonlaufen, Swapna Joshi, Jeremy S. Wilson, Zhihong Xu, Changfa Qu, David Goldstein, Minoti V. Apte, Romano C. Pirola, Cheryl S. Toi, Phoebe A. Phillips, Nicole R. Parker
Publikováno v:
Cancer research. 68(7)
Pancreatic stellate cells (PSC) produce the stromal reaction in pancreatic cancer, but their role in cancer progression is not fully elucidated. We examined the influence of PSCs on pancreatic cancer growth using (a) an orthotopic model of pancreatic
Publikováno v:
Free radical biologymedicine. 37(9)
Human lens proteins become progressively modified by tryptophan-derived UV filter compounds in an age-dependent manner. One of these compounds, kynurenine, undergoes deamination at physiological pH, and the product binds covalently to nucleophilic re
Autor:
Nicole R. Parker, Brendan Crossley, Viive M. Howell, Nelson Correia, Michael E. Buckland, Helen Wheeler
Publikováno v:
Translational Oncology. 6(6):742-IN34
BACKGROUND: MicroRNA 132 (miR-132) is dysregulated in a range of human malignancies; however, its role in glioma has not been reported. The aim of this study was to profile miR-132 expression in a cohort of patients with primary glioblastoma multifor
Autor:
Nicole R. Parker, Zhihong Xu, Alain Vonlaufen, L. Yang, Biankin, Ron Pirola, Jeremy S. Wilson, Minoti V. Apte
Publikováno v:
Pancreas. 35:433-434