Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicole Pui-Yu HO"'
Autor:
Nicole Pui-Yu Ho, Hitoshi Takizawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1125 (2022)
Haematopoietic stem cells (HSCs) reside in the bone marrow and are supported by the specialised microenvironment, a niche to maintain HSC quiescence. To deal with haematopoietic equilibrium disrupted during inflammation, HSCs are activated from quies
Externí odkaz:
https://doaj.org/article/a91bba301e9b461bbcba76a9c2f75c3a
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Tumor consists of heterogeneous cancer cells including cancer stem cells (CSCs) that can terminally differentiate into tumor bulk. Normal stem cells in normal organs regulate self-renewal within a stem cell niche. Likewise, accumulating evidence has
Externí odkaz:
https://doaj.org/article/4131a94a57cd4eb4a85b1d320ba2d53f
Autor:
Nicole Pui Yu Ho, Carmen Oi Ning Leung, Tin Lok Wong, Eunice Yuen Ting Lau, Martina Mang Leng Lei, Etienne Ho Kit Mok, Hoi Wing Leung, Man Tong, Irene Oi Lin Ng, Jing Ping Yun, Stephanie Ma, Terence Kin Wah Lee
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-14 (2021)
Abstract Emerging evidence indicates the role of cancer stem cells (CSCs) in tumor relapse and therapeutic resistance in patients with hepatocellular carcinoma (HCC). To identify novel targets against liver CSCs, an integrative analysis of publicly a
Externí odkaz:
https://doaj.org/article/e24394bef0094c0fa49316ffef7fef79
Autor:
Motohiko Oshima, Subinoy Biswas, Atsushi Iwama, Nobukazu Okamoto, Sayuri Nakata, Nicole Pui Yu Ho, Shuhei Koide, Maiko Sezaki, Takeshi Miyamoto, Hitoshi Takizawa
Publikováno v:
Stem Cells and Development. 30:725-735
Human mesenchymal stem/stromal cells (hMSCs), when engrafted into immunodeficient mice, can form ectopic bone organs with hematopoietic stem cell (HSC) supportive functions. However, the ability to...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be28f73cc784d7f44752c80785b1bb44
https://doi.org/10.1089/scd.2021.0021
https://doi.org/10.1089/scd.2021.0021
Autor:
Maiko, Sezaki, Subinoy, Biswas, Sayuri, Nakata, Motohiko, Oshima, Shuhei, Koide, Nicole Pui Yu, Ho, Nobukazu, Okamoto, Takeshi, Miyamoto, Atsushi, Iwama, Hitoshi, Takizawa
Publikováno v:
Stem cells and development. 30(14)
Human mesenchymal stem/stromal cells (hMSCs), when engrafted into immunodeficient mice, can form ectopic bone organs with hematopoietic stem cell (HSC) supportive functions. However, the ability to do so, through a cartilage intermediate, appears lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60cfc74b02019559434dcee532e7948c
https://pubmed.ncbi.nlm.nih.gov/33926240
https://pubmed.ncbi.nlm.nih.gov/33926240
Publikováno v:
Oncotarget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb20ae6d021207ef04be534929a5af2e
https://doi.org/10.18632/oncotarget.28033
https://doi.org/10.18632/oncotarget.28033
Autor:
Hitoshi Takizawa, Nicole Pui-Yu HO
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1125, p 1125 (2022)
Haematopoietic stem cells (HSCs) reside in the bone marrow and are supported by the specialised microenvironment, a niche to maintain HSC quiescence. To deal with haematopoietic equilibrium disrupted during inflammation, HSCs are activated from quies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85403cb367966ca8accac97b9115a33e
https://doi.org/10.3390/ijms23031125
https://doi.org/10.3390/ijms23031125
Autor:
Chi Ho Lin, Regina Cheuk-Lam Lo, Carmen Oi Ning Leung, Nicole Pui Yu Ho, Eunice Y. Lau, Bowie Yik Ling Cheng, Terence K. Lee, Shilpa Gurung, Hoi-Wing Leung, Lily Kwan Wai Cheng, Stephanie Ma, Irene Oi-Lin Ng
Publikováno v:
Cancer Research. 78:2332-2342
Frequent relapse and drug resistance in patients with hepatocellular carcinoma (HCC) can be attributed to the existence of tumor-initiating cells (TIC) within the tumor bulk. Therefore, targeting liver TICs may improve the prognosis of these patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550a422c0094ca4c50ff5007df3fbe9a
https://doi.org/10.1158/0008-5472.can-17-2445
https://doi.org/10.1158/0008-5472.can-17-2445
Autor:
Kenrick Kai Yuen Chan, Larry M.C. Chow, Alfred S. L. Cheng, Ka Fai To, Yue-Sun Cheung, Bin Zhang, Eunice Yuen-Ting Lau, Kwong Wai Choy, Ben C.B. Ko, Terence Kin Wah Lee, Anthony W.H. Chan, Nicole Pui Yu Ho, Yajing Zhang, Paul B.S. Lai, Hoi Kin Wong, Hang Liu, Xiaoping Zou, Rui Zhang, Vincent W. Keng
Publikováno v:
The Journal of Pathology. 243:418-430
CCCTC-binding factor (CTCF) is a DNA-binding protein that interacts with a large number of highly divergent target sequences throughout the genome. It is implicated in a variety of functions, including chromatin organization and transcriptional contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e301a73e0fb7eb273e2ac14e4feb7ed4
https://doi.org/10.1002/path.4976
https://doi.org/10.1002/path.4976
Autor:
Irene Oi-Lin Ng, Lily Kwan Wai Cheng, Mark Kin Fai Ma, Terence Kin Wah Lee, Eunice Yuen Ting Lau, Doris Hoi Wing Leung, Regina Cheuk-Lam Lo, Stephanie Ma, John A. Copland, Nicole Pui Yu Ho, Jin Ding, Jessica Lo, Chi Ho Lin
Publikováno v:
Journal of hepatology. 67(5)
Background & Aims We investigated the functional role and clinical significance of stearoyl-CoA desaturase-1 ( SCD1 ) mediated endoplasmic reticulum (ER) stress in regulating liver tumor-initiating cells (T-ICs) and sorafenib resistance, with the aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b573fcfabfd0f9cea466c8be8caea2
https://pubmed.ncbi.nlm.nih.gov/28647567
https://pubmed.ncbi.nlm.nih.gov/28647567