Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicole P. Kasica"'
Autor:
Nicole P. Kasica, Xueyan Zhou, Hannah M. Jester, Caroline E. Holland, Alexey G. Ryazanov, Tom E. Forshaw, Cristina M. Furdui, Tao Ma
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Maintenance of memory and synaptic plasticity depends on de novo protein synthesis, and accumulating evidence implicates a role of dysregulated mRNA translation in cognitive impairments associated with Alzheimer’s disease (AD). Accumulating evidenc
Externí odkaz:
https://doaj.org/article/e0f4a5e05b224f038e721e382d8107cc
Autor:
Tao Ma, C. Dirk Keene, Brenna C. Beckelman, Xueyan Zhou, Jingyun Lee, Cristina M. Furdui, Nicole P. Kasica, Helena R. Zimmermann, Wenzhong Yang, Xin Wang
Publikováno v:
J Clin Invest
AMPK is a key regulator at the molecular level for maintaining energy metabolism homeostasis. Mammalian AMPK is a heterotrimeric complex, and its catalytic α subunit exists in 2 isoforms: AMPKα1 and AMPKα2. Recent studies suggest a role of AMPKα
Autor:
Nicole P. Kasica, Xueyan Zhou, Qian Yang, Xin Wang, Wenzhong Yang, Helena R. Zimmermann, Caroline E. Holland, Elizabeth Koscielniak, Hanzhi Wu, Anderson O. Cox, Jingyun Lee, Alexey G. Ryazanov, Cristina M. Furdui, Tao Ma
Publikováno v:
J Neurochem
It is imperative to develop novel therapeutic strategies for Alzheimer's disease (AD) and related dementia syndromes based on solid mechanistic studies. Maintenance of memory and synaptic plasticity relies on de novo protein synthesis, which is parti
Publikováno v:
Alzheimer's & Dementia. 17
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Wenzhong P Yang, Hanzhi Wu, Xueyan Zhou, Caroline E Holland, Tao Ma, Nicole P. Kasica, Xin Wang, Elizabeth Koscielniak, Jingyun Lee, Alexey G. Ryazanov, Anderson Cox, Cristina M. Furdui, Helena R. Zimmermann
It is imperative to develop novel therapeutic strategies for Alzheimer’s disease (AD) and related dementia syndromes based on solid mechanistic studies. Maintenance of memory and synaptic plasticity relies on de novo protein synthesis, which is par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa52d7a4beb13907b5930b0e479e7087
https://doi.org/10.1101/2021.07.15.452522
https://doi.org/10.1101/2021.07.15.452522
Autor:
Xueyan Zhou, Tao Ma, Nicole P. Kasica, Brenna C. Beckelman, Wenzhong Yang, Alexey G. Ryazanov, C. Dirk Keene, Helena R. Zimmermann
Publikováno v:
Journal of Clinical Investigation. 129:820-833
Molecular signaling mechanisms underlying Alzheimer’s disease (AD) remain unclear. Maintenance of memory and synaptic plasticity depend on de novo protein synthesis, dysregulation of which is implicated in AD. Recent studies showed AD-associated hy
Autor:
Nicole P. Kasica, Tao Ma, Eric Klann, Fernanda G. De Felice, Sergio T. Ferreira, Mychael V. Lourenco, Danielle Dias Pinto Ferreira, Francesco Longo, Sebastian Bernales, Mauricio M. Oliveira, Paulo H. J. Mendonça, Wenzhong Yang, Gonzalo Ureta
Publikováno v:
Sci Signal
Neuronal protein synthesis is essential for long-term memory consolidation, and its dysregulation is implicated in various neurodegenerative disorders, including Alzheimer's disease (AD). Cellular stress triggers the activation of protein kinases tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ee7a7fad5148d7cf9a34485a92741f
https://europepmc.org/articles/PMC8317334/
https://europepmc.org/articles/PMC8317334/
Autor:
Nicole P. Kasica, Sebastian Bernales, Eric Klann, Francesco Longo, Mauricio M. Oliveira, Tao Ma, Danielle Dias Pinto Ferreira, Wenzhong Yang, Gonzalo Ureta, Sergio T. Ferreira, Mychael V. Lourenco, F. G. De Felice, P. H. J. Mendonca
Neuronal protein synthesis is essential for long-term memory consolidation. Conversely, dysregulation of protein synthesis has been implicated in a number of neurodegenerative disorders, including Alzheimer’s disease (AD). Several types of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d4e5487c6bd4565b6369b0479cdb4f
https://doi.org/10.1101/2020.10.19.344564
https://doi.org/10.1101/2020.10.19.344564
Autor:
Xueyan Zhou, Helena R. Zimmermann, Tao Ma, Alexey G. Ryazanov, Lucas Dufresne Galli, Nicole P. Kasica, Wenzhong Yang, Brenna C. Beckelman
Publikováno v:
Journal of neurochemistry. 146(2)
Characterization of the molecular signaling pathways underlying protein synthesis-dependent forms of synaptic plasticity, such as late long-term potentiation (L-LTP), can provide insights not only into memory expression/maintenance under physiologica