Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicole Novaresi"'
Autor:
Tomohisa Toda, Tracy A. Bedrosian, Simon T. Schafer, Michael S. Cuoco, Sara B. Linker, Saeed Ghassemzadeh, Lisa Mitchell, Jack T. Whiteley, Nicole Novaresi, Aidan H. McDonald, Iryna S. Gallina, Hyojung Yoon, Mark E. Hester, Monique Pena, Christina Lim, Emelia Suljic, Abed AlFatah Mansour, Matthieu Boulard, Sarah L. Parylak, Fred H. Gage
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113774- (2024)
Summary: Long interspersed nuclear element-1 (L1 or LINE-1) is a highly abundant mobile genetic element in both humans and mice, comprising almost 20% of each genome. L1s are silenced by several mechanisms, as their uncontrolled expression has the po
Externí odkaz:
https://doaj.org/article/6688623518d44adfa7c2bcdc893f7bd4
Autor:
Kathryn A. O'Donnell, Robert E. Hammer, Jingfei Zhu, Emily Stein, James A. Richardson, Shruthy Suresh, Nicole Novaresi, Bethany Smith, Bret M. Evers, Mahesh S. Padanad, Xiaorong Zhou
PROTOCADHERIN 7 (PCDH7), a transmembrane receptor and member of the Cadherin superfamily, is frequently overexpressed in lung adenocarcinoma and is associated with poor clinical outcome. Although PCDH7 was recently shown to promote transformation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba988a9daa98bf8fd525da178edfe78
https://doi.org/10.1158/1541-7786.c.6541185
https://doi.org/10.1158/1541-7786.c.6541185
Autor:
Kathryn A. O'Donnell, Robert E. Hammer, Jingfei Zhu, Emily Stein, James A. Richardson, Shruthy Suresh, Nicole Novaresi, Bethany Smith, Bret M. Evers, Mahesh S. Padanad, Xiaorong Zhou
S1. Generation of PCDH7LSL mice and analysis of lung tumors in vivo. S2. TUNEL staining of lung tumors. S3. Validation of CRISPR/Cas9-editing of Pcdh7. S4. Diminished invasiveness in Pcdh7 depleted KP tumors. S5. Sequences of gene-edited alleles in K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb74888c2e2b8ecaa62c4d2cc1e4b28
https://doi.org/10.1158/1541-7786.22515798.v1
https://doi.org/10.1158/1541-7786.22515798.v1
Autor:
Ryan J. Golden, Yang Xin Fu, Xiaowei Zhan, Bret M. Evers, Sojeong Jun, Carmen Behrens, Jingfei Zhu, Guanghua Xiao, Michael Peyton, Joshua T. Mendell, Vanessa Schmid, Chelsea M. Karacz, Adwait Amod Sathe, Kathryn A. O'Donnell, Chao Xing, Nicole Novaresi, Lin Zhong, Bethany Smith, Shruthy Suresh, Ignacio I. Wistuba, Zhuoyu Wen, John D. Minna, Yang Xie, Changzheng Lu, Beibei Chen
Publikováno v:
Nat Cancer
Cancer cells express high levels of programmed death ligand 1 (PD-L1), a ligand of the programmed cell death protein 1 (PD-1) receptor on T cells, allowing tumors to suppress T cell activity. Clinical trials utilizing antibodies that disrupt the PD-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f31a79badef7db84da2ac56d475065f
https://doi.org/10.1038/s43018-020-0056-0
https://doi.org/10.1038/s43018-020-0056-0
Autor:
Xiaorong Zhou, Kathryn A. O'Donnell, Jingfei Zhu, Bethany Smith, Shruthy Suresh, James A. Richardson, Robert E. Hammer, Nicole Novaresi, Mahesh S. Padanad, Emily Stein, Bret M. Evers
PROTOCADHERIN 7 (PCDH7), a transmembrane receptor and member of the Cadherin superfamily, is frequently overexpressed in lung adenocarcinoma and is associated with poor clinical outcome. Although PCDH7 was recently shown to promote transformation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc2286e134bcbf1d1db910cbf5a9f48
https://europepmc.org/articles/PMC6359939/
https://europepmc.org/articles/PMC6359939/