Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Nicole Naumann"'
Autor:
Johannes Lübke, Nicole Naumann, Oliver Hoffmann, Hans-Peter Horny, Karl Sotlar, Martina Rudelius, Georgia Metzgeroth, Alice Fabarius, Wolf-Karsten Hofmann, Andreas Reiter, Juliana Schwaab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In 70 patients with KIT D816V positive systemic mastocytosis (SM) including 36 patients with advanced SM (AdvSM), we correlated the extent of reported mucosal mast cell ([m]MC) infiltration of the upper and/or lower gastrointestinal tract (U
Externí odkaz:
https://doaj.org/article/401bed6d276b43f0807e3552a3d9913f
Autor:
Johannes Lübke, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, Timo Brand, Hans-Peter Horny, Karl Sotlar, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Publikováno v:
HemaSphere, Vol 7, p e472819b (2023)
Externí odkaz:
https://doaj.org/article/340457ea6c1f4b7cbd4ba14f78640ecd
Autor:
Nicole Naumann, Ulrike Bross‐Bach, Wolfgang Seifarth, Alice Fabarius, Wolf‐Karsten Hofmann, Susanne Saußele, Birgit Spiess
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1339-1342 (2022)
Abstract Quantitative reverse transcription polymerase chain reaction (qRT‐PCR) of BCR‐ABL1 transcript level is an essential part of routine disease monitoring in patients with chronic myeloid leukemia. One patient sample (e13a2 transcript detect
Externí odkaz:
https://doaj.org/article/b3ffd407b32e46d39100c0feee65d6d9
Autor:
Julia Riffel, Johannes Lübke, Nicole Naumann, Sebastian Kreil, Georgia Metzgeroth, Alice Fabarius, Karl Sotlar, Hans-Peter Horny, Mohamad Jawhar, Daniel Overhoff, Stefan Schoenberg, Wolf-Karsten Hofmann, Thomas Henzler, Juliana Schwaab, Andreas Reiter, Philipp Riffel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Systemic mastocytosis (SM) is characterized by multifocal accumulation of neoplastic mast cells (MCs), predominately affecting the bone marrow (BM). Imaging with computed tomography (CT) is used for assessment of bone mineral density and str
Externí odkaz:
https://doaj.org/article/2c12322153304911a38febee511dbcc1
Autor:
Birgit Spiess, Sébastien Rinaldetti, Nicole Naumann, Norbert Galuschek, Ute Kossak-Roth, Patrick Wuchter, Irina Tarnopolscaia, Diana Rose, Astghik Voskanyan, Alice Fabarius, Wolf-Karsten Hofmann, Susanne Saußele, Wolfgang Seifarth
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214305 (2019)
In chronic myeloid leukemia (CML), the duration of deep molecular response (MR) before treatment cessation (MR4 or deeper, corresponding to BCR-ABL1 ≤ 0.01% on the International Scale (IS)) is considered as a prognostic factor for treatment free re
Externí odkaz:
https://doaj.org/article/9fb29c6c4d2143cf9d629d111cd1c100
Autor:
Nicole Naumann, Johannes Lübke, Sofie Baumann, Juliana Schwaab, Oliver Hoffmann, Sebastian Kreil, Vito Dangelo, Lukas Reiter, Peter Bugert, Thomas Kristensen, Karl Sotlar, Verena Haselmann, Sven Schneider, Georgia Metzgeroth, Christel Weiss, Henning D. Popp, Alice Fabarius, Wolf-Karsten Hofmann, Nicholas C. P. Cross, Andreas Reiter, Mohamad Jawhar
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2562 (2021)
In systemic mastocytosis (SM), qualitative and serial quantitative assessment of the KIT D816V mutation is of diagnostic and prognostic relevance. We investigated peripheral blood and bone marrow samples of 161 patients (indolent SM (ISM), n = 40; ad
Externí odkaz:
https://doaj.org/article/df45f5bc8edd46bf9a7afe3c33db31a7
Autor:
Henning D. Popp, Mathias Meyer, Susanne Brendel, Wiltrud Prinzhorn, Nicole Naumann, Christel Weiss, Wolfgang Seifarth, Stefan O. Schoenberg, Wolf-K. Hofmann, Thomas Henzler, Alice Fabarius
Publikováno v:
European Journal of Radiology Open, Vol 3, Iss , Pp 134-137 (2016)
Purpose: Computed tomography (CT) scans are an important source of ionizing irradiation (IR) in medicine that can induce a variety of DNA damage in human tissues. With technological improvements CT scans at reduced absorbed doses became feasible pres
Externí odkaz:
https://doaj.org/article/5f6a3edfe98745669ee9127138d6f17f
Autor:
Henning D. Popp, Vanessa Kohl, Nicole Naumann, Johanna Flach, Susanne Brendel, Helga Kleiner, Christel Weiss, Wolfgang Seifarth, Susanne Saussele, Wolf-Karsten Hofmann, Alice Fabarius
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1177 (2020)
DNA damage and alterations in the DNA damage response (DDR) are critical sources of genetic instability that might be involved in BCR-ABL1 kinase-mediated blastic transformation of chronic myeloid leukemia (CML). Here, increased DNA damage is detecte
Externí odkaz:
https://doaj.org/article/1b45931184f6452fad970a809b69e1e8
Autor:
Birgit Spiess, Nicole Naumann, Norbert Galuschek, Sébastien Rinaldetti, Ute Kossak-Roth, Irina Tarnopolscaia, Elena Felde, Alice Fabarius, Wolf-Karsten Hofmann, Susanne Saußele, Wolfgang Seifarth
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196326 (2018)
Quantitative real-time polymerase chain reaction (qRT-PCR) is state of the art in molecular monitoring of minimal residual disease in chronic myeloid leukemia (CML). In this context, maintenance of assay fidelity and detection of technical inaccuracy
Externí odkaz:
https://doaj.org/article/f98d248d87bb4c9e977372e56985b731
Autor:
Mohamad Jawhar, Juliana Schwaab, Manja Meggendorfer, Nicole Naumann, Hans-Peter Horny, Karl Sotlar, Torsten Haferlach, Karla Schmitt, Alice Fabarius, Peter Valent, Wolf-Karsten Hofmann, Nicholas C.P. Cross, Georgia Metzgeroth, Andreas Reiter
Publikováno v:
Haematologica, Vol 102, Iss 6 (2017)
Mast cell leukemia is a rare variant of advanced systemic mastocytosis characterized by at least 20% of mast cells in a bone marrow smear. We evaluated clinical and molecular characteristics of 28 patients with (n=20, 71%) or without an associated he
Externí odkaz:
https://doaj.org/article/26bdaedd201b41ba9b1ae550c53e1624