Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nicole Malandro"'
Autor:
Karen E Tkach, Debashis Barik, Guillaume Voisinne, Nicole Malandro, Matthew M Hathorn, Jesse W Cotari, Robert Vogel, Taha Merghoub, Jedd Wolchok, Oleg Krichevsky, Grégoire Altan-Bonnet
Publikováno v:
eLife, Vol 3 (2014)
Variability within isogenic T cell populations yields heterogeneous ‘local’ signaling responses to shared antigenic stimuli, but responding clones may communicate ‘global’ antigen load through paracrine messengers, such as cytokines. Such coo
Externí odkaz:
https://doaj.org/article/93b0bebb910d43acb92f2212db05dbe5
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 84K, Percentage of CD4+Foxp3+ Tregs in IgG vs DTA-1 treated tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fc51fde8f53873febd317d76bb8dd8
https://doi.org/10.1158/2326-6066.22535843.v1
https://doi.org/10.1158/2326-6066.22535843.v1
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 143K, Foxp3 loss in Tregs is tumor and DTA-1 dose dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6797bf04ea04a40e0d2d70aae72ceefa
https://doi.org/10.1158/2326-6066.22535846
https://doi.org/10.1158/2326-6066.22535846
Autor:
Taha Merghoub, Jedd D. Wolchok, Robert Olmsted, Maureen F. Maughan, Shakuntala Tiwari, Daniel Hirschhorn-Cymerman, Nicole Malandro, Sadna Budhu, Arvin Yang, Roberta Zappasodi, Francesca Avogadri
Induction of potent immune responses to self-antigens remains a major challenge in tumor immunology. We have shown that a vaccine based on alphavirus replicon particles (VRP) activates strong cellular and humoral immunity to tyrosinase-related protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f67f6f7cb77e9b9e6530278c4fd00f
https://doi.org/10.1158/2326-6066.c.6548896
https://doi.org/10.1158/2326-6066.c.6548896
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
PDF file - 48K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92da90883bb385af050d8d9c41be5fc3
https://doi.org/10.1158/2326-6066.22535840.v1
https://doi.org/10.1158/2326-6066.22535840.v1
Autor:
Taha Merghoub, Jedd D. Wolchok, Robert Olmsted, Maureen F. Maughan, Shakuntala Tiwari, Daniel Hirschhorn-Cymerman, Nicole Malandro, Sadna Budhu, Arvin Yang, Roberta Zappasodi, Francesca Avogadri
PDF file - 428K, Supplementary Figure S1. Depigmentation after combination therapy. Supplementary Figure S2. Tumor immune infiltrate after immunomodulation. Supplementary Figure S3. PD-1 expression on T cell subsets. Supplementary Figure S4. Effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d28c53d772054d517b83ba448696a1
https://doi.org/10.1158/2326-6066.22538794.v1
https://doi.org/10.1158/2326-6066.22538794.v1
Autor:
Jedd D. Wolchok, Taha Merghoub, Alan N. Houghton, Xia Yang, Hong Zhong, Adam Cohen, Nicole Malandro, Campbell Bryson, Cailian Liu, Sadna Budhu, David A. Schaer
Ligation of GITR (glucocorticoid-induced TNF receptor-related gene, or TNFRSF18) by agonist antibody has recently entered into early-phase clinical trials for the treatment of advanced malignancies. Although the ability of GITR modulation to induce t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ce48bcaa8fde54e58fe3e69611bddb
https://doi.org/10.1158/2326-6066.c.6547961.v1
https://doi.org/10.1158/2326-6066.c.6547961.v1
Autor:
Sara E. Schad, Andrew Chow, Levi Mangarin, Heng Pan, Jiajia Zhang, Nicholas Ceglia, Justina X. Caushi, Nicole Malandro, Roberta Zappasodi, Mathieu Gigoux, Daniel Hirschhorn, Sadna Budhu, Masataka Amisaki, Monica Arniella, David Redmond, Jamie Chaft, Patrick M. Forde, Justin F. Gainor, Matthew D. Hellmann, Vinod Balachandran, Sohrab Shah, Kellie N. Smith, Drew Pardoll, Olivier Elemento, Jedd D. Wolchok, Taha Merghoub
Publikováno v:
The Journal of experimental medicine. 219(6)
Transcription factors ThPOK and Runx3 regulate the differentiation of “helper” CD4+ and “cytotoxic” CD8+ T cell lineages respectively, inducing single positive (SP) T cells that enter the periphery with the expression of either the CD4 or CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc8c0fcf62399fc957612e239fea52b
https://pubmed.ncbi.nlm.nih.gov/35604411
https://pubmed.ncbi.nlm.nih.gov/35604411
Autor:
Gabrielle Rizzuto, Czrina Cortez, Judith T. Murphy, Grégoire Altan-Bonnet, Cailian Liu, Nicholas F. Kuhn, Taha Merghoub, Nicole Malandro, Sadna Budhu, Xia Yang, Hong Zhong, Jedd D. Wolchok
Publikováno v:
Immunity. 44(1):179-193
Current approaches to cancer immunotherapy aim to engage the natural T cell response against tumors. One limitation is the elimination of self-antigen-specific T cells from the immune repertoire. Using a system in which precursor frequency can be man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7aec7ddc3d2b0a8c6ba35cd4fc2c8da
Autor:
Richard Schlegel, Nicole Malandro, Kihyuck Kwak, Subhashini Jagu, Kenneth E. Palmer, Hang Yuan, Warner K. Huh, Richard B.S. Roden, M. Saveria Campo
Publikováno v:
Virology. 420(1):43-50
It is unclear what level of neutralizing antibody is sufficient to protect cattle from experimental bovine papillomavirus type 4 (BPV4) challenge. Markedly lower, and often undetected, serum neutralizing antibody titers were associated with protectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9a9226110445857880339bdc188e08