Výsledky vyhledávání - "Nicole Maeding"

Akademický článek

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation

Publikováno v: Journal of Extracellular Vesicles, Vol 11, Iss 4, Pp n/a-n/a (2022)

Abstract Nanoparticles can acquire a plasma protein corona defining their biological identity. Corona functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we demonstrate that nano‐sized EVs from therapy‐grade

Externí odkaz: https://doaj.org/article/1197d81877274487b4ca26349612d5f1

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Akademický článek

Synergy of Human Platelet-Derived Extracellular Vesicles with Secretome Proteins Promotes Regenerative Functions

Autor: Fausto Gueths Gomes, André Cronemberger Andrade, Martin Wolf, Sarah Hochmann, Linda Krisch, Nicole Maeding, Christof Regl, Rodolphe Poupardin, Patricia Ebner-Peking, Christian G. Huber, Nicole Meisner-Kober, Katharina Schallmoser, Dirk Strunk

Publikováno v: Biomedicines, Vol 10, Iss 2, p 238 (2022)

Platelet-rich plasma is a promising regenerative therapeutic with controversial efficacy. We and others have previously demonstrated regenerative functions of human platelet lysate (HPL) as an alternative platelet-derived product. Here we separated e

Externí odkaz: https://doaj.org/article/66abe7b053874210ab31375db1164318

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Akademický článek

Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles

Autor: Heide-Marie Binder, Nicole Maeding, Martin Wolf, André Cronemberger Andrade, Balazs Vari, Linda Krisch, Fausto Gueths Gomes, Constantin Blöchl, Katharina Muigg, Rodolphe Poupardin, Anna M. Raninger, Thomas Heuser, Astrid Obermayer, Patricia Ebner-Peking, Lisa Pleyer, Richard Greil, Christian G. Huber, Katharina Schallmoser, Dirk Strunk

Publikováno v: Cells, Vol 10, Iss 12, p 3321 (2021)

Acute myeloid leukemia (AML) cells can secrete trophic factors, including extracellular vesicles (EVs), instructing the stromal leukemic niche. Here, we introduce a scalable workflow for purification of immunomodulatory AML-EVs to compare their pheno

Externí odkaz: https://doaj.org/article/71159c638ab8466cb9e3a5c7f6d4c194

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Data from BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Autor: Alexander Egle, Richard Greil, Tanja N. Hartmann, Andreas Villunger, Nadja Zaborsky, Bettina Jansko, Clemens Hufnagl, Nicole Maeding, Yuan Qi, Michael Leisch, Nathalie Wacht, Daniela Asslaber

Purpose:Chronic lymphocytic leukemia (CLL) pathophysiology is characterized by a complex crosstalk of tumor cells with the microenvironment. In this regard, NF-κB signaling is considered as important signaling axis, with a variety of key molecules a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2630da3f9d678951e655180b8808779c
https://doi.org/10.1158/1078-0432.c.6528042

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Lack of Bmf Facilitates the Selection of Highly Responsive B-Cell Receptor Clones in Chronic Lymphocytic Leukemia

Autor: Alexander Egle, Daniela Asslaber, Nicole Maeding, Nadja Zaborsky, Richard Greil, Andreas Villunger

Publikováno v: Blood. 138:1543-1543

Introduction: Chronic lymphocytic leukemia (CLL) is a disease of inhibited cell death, increased proliferation and high importance of interactions with the microenvironment e.g. with T-cells or stromal cells. A central effector in this concert is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e8d915f4c7898f49af6703978e144ad
https://doi.org/10.1182/blood-2021-152216

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Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide

Autor: Thomas Verwanger, Cornelia Roschger, Mario Schubert, Barbara Krammer, Brigitta Elsässer, Chiara Cabrele, Nicole Maeding, Saskia Neukirchen

Publikováno v: ChemMedChem. 12:1497-1503

The Id proteins (Id1-4) are cell-cycle regulators that play a key role during development, in cancer and vascular disorders. They contain a conserved helix-loop-helix (HLH) domain that folds into a parallel four-helix bundle upon self- or hetero-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736308df01c90321d6eda8803e90e492
https://doi.org/10.1002/cmdc.201700305

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BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation

Autor: Daniela, Asslaber, Nathalie, Wacht, Michael, Leisch, Yuan, Qi, Nicole, Maeding, Clemens, Hufnagl, Bettina, Jansko, Nadja, Zaborsky, Andreas, Villunger, Tanja N, Hartmann, Richard, Greil, Alexander, Egle

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(6)

Chronic lymphocytic leukemia (CLL) pathophysiology is characterized by a complex crosstalk of tumor cells with the microenvironment. In this regard, NF-κB signaling is considered as important signaling axis, with a variety of key molecules aberrantl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21464166f8ab722d7654b9d73b1fa175
https://pubmed.ncbi.nlm.nih.gov/30487125

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Boosting Tumor-Specific Immunity Using PDT

Autor: Nicole Maeding, Thomas Verwanger, Barbara Krammer

Publikováno v: Cancers, Vol 8, Iss 10, p 91 (2016)
Cancers

Photodynamic therapy (PDT) is a cancer treatment with a long-standing history. It employs the application of nontoxic components, namely a light-sensitive photosensitizer and visible light, to generate reactive oxygen species (ROS). These ROS lead to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc358b5b001bcde11e71737c420b9b3
https://doi.org/10.3390/cancers8100091

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