Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicole M. Scarborough"'
Autor:
Chittaranjan Das, Gregery T. Buzzard, Robert F. Fischetti, Michael J. Sheedlo, David J. Kissick, Dong Hye Ye, Nicole M. Scarborough, G. M. Dilshan P. Godaliyadda, Shijie Zhang, Azhad U. Chowdhury, Charles A. Bouman, Justin A. Newman, Garth J. Simpson
Publikováno v:
Computational Imaging
A supervised learning approach for dynamic sampling (SLADS) was developed to reduce X-ray exposure prior to data collection in protein structure determination. Implementation of this algorithm allowed reduction of the X-ray dose to the central core o
Autor:
Nicole M. Scarborough, Changqin Ding, Jerald C. Martin, Garth J. Simpson, Gregory S. Eakins, Zhengtian Song, Fengyuan Deng
Publikováno v:
High-Speed Biomedical Imaging and Spectroscopy III: Toward Big Data Instrumentation and Management.
Fluorescence hyperspectral imaging is a powerful tool for in vivo biological studies. The ability to recover the full spectra of the fluorophores allows accurate classification of different structures and study of the dynamic behaviors during various
Autor:
Chittaranjan Das, Justin A. Newman, Charles A. Bouman, Nicole M. Scarborough, G. M. Dilshan P. Godaliyadda, Shijie Zhang, Robert F. Fischetti, Michael J. Sheedlo, David J. Kissick, Garth J. Simpson, Azhad U. Chowdhury, Gregery T. Buzzard, Dong Hye Ye
Publikováno v:
Journal of synchrotron radiation. 24(Pt 1)
A sparse supervised learning approach for dynamic sampling (SLADS) is described for dose reduction in diffraction-based protein crystal positioning. Crystal centering is typically a prerequisite for macromolecular diffraction at synchrotron facilitie
Autor:
Nicholas Roman Pogranichniy, Garth J. Simpson, Chittaranjan Das, Richard G. Closser, Justin A. Newman, Nicole M. Scarborough, Rashmi K. Shrestha
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 71(Pt 7)
The second-harmonic generation (SHG) activity of protein crystals was found to be enhanced by up to ∼1000-fold by the intercalation of SHG phores within the crystal lattice. Unlike the intercalation of fluorophores, the SHG phores produced no signi
Autor:
Gregory S. Eakins, Jerald C. Martin, Changqin Ding, Fengyuan Deng, Nicole M. Scarborough, Zhengtian Song, Garth J. Simpson
Publikováno v:
Optics Express. 25:32243
A spatial-spectral multiplexing two-photon excited fluorescence (TPEF) hyperspectral imaging system was demonstrated at 17 frames per second (fps) with over 2,000 effective spectral channels. The system exploited the hardware used in beam-scanning mi
Autor:
Nicole M. Scarborough, Nicholas Pogranichnyi, Justin A. Newman, Garth J. Simpson, Richard G. Closser
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 70:C1154-C1154
Recently, second harmonic generation (SHG) microscopy has become a useful tool in the field of structural biology for the detection of protein crystals. SHG, or the frequency doubling of light, is a process specific to crystalline media lacking inver