Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nicole M. Revie"'
Autor:
Jessie MacAlpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1edd977e074749009192e38dcc7e589d
Autor:
Nicole M. Revie, Kali R. Iyer, Michelle E. Maxson, Jiabao Zhang, Su Yan, Caroline M. Fernandes, Kirsten J. Meyer, Xuefei Chen, Iwona Skulska, Meea Fogal, Hiram Sanchez, Saif Hossain, Sheena Li, Yoko Yashiroda, Hiroyuki Hirano, Minoru Yoshida, Hiroyuki Osada, Charles Boone, Rebecca S. Shapiro, David R. Andes, Gerard D. Wright, Justin R. Nodwell, Maurizio Del Poeta, Martin D. Burke, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
There is an urgent need for novel strategies to combat life-threatening fungal infections. Here, Revie et al. identify a compound that induces alterations in fungal membranes, synergizes with azole antifungals against the pathogen Candida albicans, a
Externí odkaz:
https://doaj.org/article/8bca44075efb4f07a12ae3b736c09d4d
Autor:
Ci Fu, Xiang Zhang, Amanda O. Veri, Kali R. Iyer, Emma Lash, Alice Xue, Huijuan Yan, Nicole M. Revie, Cassandra Wong, Zhen-Yuan Lin, Elizabeth J. Polvi, Sean D. Liston, Benjamin VanderSluis, Jing Hou, Yoko Yashiroda, Anne-Claude Gingras, Charles Boone, Teresa R. O’Meara, Matthew J. O’Meara, Suzanne Noble, Nicole Robbins, Chad L. Myers, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The analysis of essential genes in pathogens can be used to discover potential antimicrobial targets. Here, the authors use a machine learning model and chemogenomic analyses to generate genome-wide gene essentiality predictions for the fungal pathog
Externí odkaz:
https://doaj.org/article/30b53e35a0bc440e930c93cb62d5cbf8
Autor:
Jessie MacAlpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacill
Externí odkaz:
https://doaj.org/article/715093acde814215a41b6a51e866385d
Autor:
Antonia C. Du Bois, Alice Xue, Chester Pham, Nicole M. Revie, Kirsten J. Meyer, Yoko Yashiroda, Charles Boone, Justin R. Nodwell, Peter Stogios, Alexei Savchenko, Nicole Robbins, Kali R. Iyer, Leah E. Cowen
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Fungal infections contribute to over 1.5 million deaths annually, with Candida albicans representing one of the most concerning human fungal pathogens. While normally commensal in nature, compromise of host immunity can result in C. albicans
Externí odkaz:
https://doaj.org/article/dbf0dfd19fe74b018af7b652dd1d066f
Autor:
Nicole M. Revie, Leah E. Cowen
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 706-708 (2021)
Externí odkaz:
https://doaj.org/article/b4a53dde46fa44d687506f9c38ca7a7d
Autor:
Nicole M. Revie, Nicole Robbins, Luke Whitesell, John R. Frost, Solomon D. Appavoo, Andrei K. Yudin, Leah E. Cowen
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Opportunistic pathogens of the genus Candida reign as the leading cause of mycotic disease and are associated with mortality rates greater than 40%, even with antifungal intervention. This is in part due to the limited arsenal of antifungals
Externí odkaz:
https://doaj.org/article/7fcd951d919f45c5a4cff456bb66d52f
Autor:
Harley O'Connor Mount, Nicole M Revie, Robert T Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E Cowen
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007319 (2018)
Invasive fungal infections caused by the pathogen Candida albicans have transitioned from a rare curiosity to a major cause of human mortality. This is in part due to the emergence of resistance to the limited number of antifungals available to treat
Externí odkaz:
https://doaj.org/article/944bb316161947ada1565c081716ea33
Autor:
Hiram Sanchez, Robert T. Todd, Peter J. Stogios, Leah E. Cowen, Luke Whitesell, Zhongle Liu, Justin R. Nodwell, Nicole M. Revie, Nicole Robbins, Thomas A. Tompkins, Junko Yano, Amanda O. Veri, Anna Selmecki, Martin Daniel-Ivad, Jessie MacAlpine, David R. Andes, Paul L. Fidel, Teresa R. O’Meara, Alexei Savchenko
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacillus are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429c332d0d9482bee9f0ee34c76031b1
https://doi.org/10.1038/s41467-021-26390-w
https://doi.org/10.1038/s41467-021-26390-w
Publikováno v:
Nature Reviews. Microbiology
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an enormous impact on human health worldwide. The global burden of cryptococcal meningitis is almost a quarter of a million cases and 181,000 deaths annually, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220514510a345fd5254dd9431c88a782
https://pubmed.ncbi.nlm.nih.gov/33558691
https://pubmed.ncbi.nlm.nih.gov/33558691