Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicole M. Ramocki"'
Autor:
Brooks Scull, Ginny H. Lee, P. Kay Lund, James G. Simmons, Kirk K. McNaughton, Heather R. Wilkins, Scott T. Magness, Nicole M. Ramocki
Publikováno v:
Endocrinology. 149:261-267
Reduced apoptosis of crypt stem/progenitor cells and elevated insulin and IGFs are linked to colon cancer risk. Insulin receptor substrate-1 (IRS-1) mediates the actions of insulin, IGF-I, and IGF-II, but the role of endogenous IRS-1 in crypt apoptos
Autor:
Kirk K. McNaughton, James G. Simmons, Christopher J. Greenhalgh, Nicole M. Ramocki, Carmen Z. Michaylira, P. Kay Lund, C. Kirby Tanner, John T. Woosley
Publikováno v:
Endocrinology. 147:1632-1641
GH may improve intestinal growth or function in patients with short bowel syndrome. Excessive trophic effects of GH or IGF-I may contribute to neoplastic growth or increased colorectal cancer risk in acromegaly. Identification of mechanisms that limi
Autor:
Nicole M. Ramocki, Brooks Scull, Kirk K. McNaughton, James G. Simmons, Victoria A. Newton, P. Kay Lund
Publikováno v:
The American journal of pathology. 176(5)
Epigenetic in vitro and in vivo studies suggest that suppressor of cytokine signaling-2 (SOCS2) may normally limit tumorigenesis in the intestine; however, this theory has not been directly tested. We hypothesized that SOCS2 deficiency promotes spont
Autor:
P. Kay Lund, Adam Burkholder, Brooks Scull, Nicole M. Ramocki, Douglas R. Morgan, Gerald Cecil, Howard H. Zhang
Background Current capsule endoscopy (CE) provides minimally invasive technology for GI imaging but has limited ability to discriminate different types of polyps. Near infrared fluorescent (NIRF) probes activated by biomarkers upregulated in adenomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772f30257e6c1971c631e86929ed5122
https://europepmc.org/articles/PMC2754293/
https://europepmc.org/articles/PMC2754293/
Autor:
Kirk K. McNaughton, C. Randall Fuller, P. Kay Lund, Brooks Scull, Carmen Z. Michaylira, Nicole M. Ramocki, James G. Simmons
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 291(3)
Suppressors of cytokine signaling (SOCS) typically limit cytokine receptor signaling via the JAK-STAT pathway. Considerable evidence demonstrates that SOCS2 limits growth hormone (GH) action on body and organ growth. Biochemical evidence that SOCS2 b