Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nicole M. Ralbovsky"'
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Analysis of virus-like particles (VLPs) is an essential task in optimizing their implementation as vaccine antigens for virus-initiated diseases. Interrogating VLP collections for elasticity by probing with a rigid atomic force microscopy (A
Externí odkaz:
https://doaj.org/article/8f980b8f2fb345569f2bcfc0e82d6513
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy and affects boys in infancy or early childhood. Current methods for diagnosing DMD are often laborious, expensive, invasive, and typically diagnose th
Externí odkaz:
https://doaj.org/article/1f0d6267f7f9453584dbf817b857cc6d
Publikováno v:
Genes, Vol 13, Iss 8, p 1342 (2022)
Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy, typically affecting males in infancy. The disease causes progressive weakness and atrophy of skeletal muscles, with approximately 20,000 new cases diagnosed yearly. Curr
Externí odkaz:
https://doaj.org/article/4cdc6ef8d5674a0686d294f22924c05b
Autor:
Elena Ryzhikova, Nicole M. Ralbovsky, Lenka Halámková, Dzintra Celmins, Paula Malone, Eric Molho, Joseph Quinn, Earl A. Zimmerman, Igor K. Lednev
Publikováno v:
Applied Sciences, Vol 9, Iss 16, p 3256 (2019)
Alzheimer’s disease (AD) is the most common form of dementia worldwide and is characterized by progressive cognitive decline. Along with being incurable and lethal, AD is difficult to diagnose with high levels of accuracy. Blood serum from Alzheime
Externí odkaz:
https://doaj.org/article/dd5f194958eb41949e7cd74fd8799483
Autor:
Anumita Saha-Shah, Joseph P Smith, Janelle Konietzko, Emily Costell, Patrick M McHugh, Justin P Lo-Mont, Nicole M Ralbovsky, Louis Obando, Sheng-ching Wang, Emmanuel Appiah-Amponsah, Ian Mangion
Publikováno v:
Bioanalysis.
Aims: Process analytical technology (PAT) is increasingly being adopted within the pharmaceutical industry to build quality into a process. Development of PAT that provides real-time in situ analysis of critical quality attributes are highly desirabl
Autor:
Nicole M. Ralbovsky, Joseph P. Smith
Publikováno v:
Pharmaceutical Research.
Autor:
Nicole M. Ralbovsky, Randal J. Soukup, Justin P. Lomont, Mackenzie L. Lauro, Amanda Gulasarian, Anumita Saha-Shah, Michael A. Winters, Douglas D. Richardson, Sheng-Ching Wang, Ian Mangion, Joseph P. Smith
Publikováno v:
The Analyst. 147:378-386
Process analytical technology was used to monitor formation of a stable emulsion product, with results providing improved understanding of emulsion-based vaccine adjuvant formation processes.
Autor:
Igor K. Lednev, Nicole M. Ralbovsky
Publikováno v:
Applied Spectroscopy. 75:929-946
Type II diabetes mellitus (T2DM) is a metabolic disorder that is characterized by chronically elevated glucose caused by insulin resistance. Although T2DM is manageable through insulin therapy, the disorder itself is a risk factor for much more dange
Autor:
Nicole M. Ralbovsky, Justin P. Lomont, Xiaodong Bu, Jennifer V. Obligacion, Zachary E. X. Dance, Joseph P. Smith, Benjamin F. Mann
Publikováno v:
Organic Process Research & Development. 25:1402-1413
Autor:
Nicole M. Ralbovsky, Joseph P. Smith
Publikováno v:
Talanta. 252:123787
The development of a safe and effective active pharmaceutical ingredient (API) to be used for addressing a disease is of the utmost importance in the pharmaceutical industry. Oftentimes, the synthetic pathway required for API development involves the