Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicole M. Martinez"'
Autor:
Andrei Thomas-Tikhonenko, Stephan A. Grupp, John M. Maris, Kristen W. Lynch, Yoseph Barash, Crystal Mackall, Terry Fry, Elad Jacoby, David Allman, Jan J. Melenhorst, Simon F. Lacey, Saar Gill, Alejandro Barrera, Pichai Raman, Shannon L. Maude, Ted J. Hofmann, Jessica Perazzelli, Elaine Y. Chung, Colleen T. Harrington, Nicole M. Martinez, Matthew R. Gazzara, Marco Ruella, Claudia Lanauze, Robyn Sussman, Glendon Wu, Derek Oldridge, Asen Bagashev, Kathryn L. Black, David M. Barrett, Elena Sotillo
Supplementary Table 1. DNA fragments synthesized and inserted into MSCV-CD19-IRES-DsRedFP via EcoRI/BglII or BglII/XhoI digestion, and later moved into pMX-IRES-Blast via EcoRI/XhoI cloning. Supplementary Table 2. Sets of primers used for PCR amplifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35429cb5175b3bba939b9bbf54000841
https://doi.org/10.1158/2159-8290.22531644
https://doi.org/10.1158/2159-8290.22531644
Autor:
Andrei Thomas-Tikhonenko, Stephan A. Grupp, John M. Maris, Kristen W. Lynch, Yoseph Barash, Crystal Mackall, Terry Fry, Elad Jacoby, David Allman, Jan J. Melenhorst, Simon F. Lacey, Saar Gill, Alejandro Barrera, Pichai Raman, Shannon L. Maude, Ted J. Hofmann, Jessica Perazzelli, Elaine Y. Chung, Colleen T. Harrington, Nicole M. Martinez, Matthew R. Gazzara, Marco Ruella, Claudia Lanauze, Robyn Sussman, Glendon Wu, Derek Oldridge, Asen Bagashev, Kathryn L. Black, David M. Barrett, Elena Sotillo
Supplementary Figure 1. Enhanced skipping of exons 2 and 5-6 in post-CART-19 leukemias. Supplementary Figure 2. Analysis of splicing factors involved in alternative splicing of CD19-exon2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cbabee5eac26a167ce28f0ee82262e
https://doi.org/10.1158/2159-8290.22531647.v1
https://doi.org/10.1158/2159-8290.22531647.v1
Publikováno v:
Annu Rev Genet
Recent advances in pseudouridine detection reveal a complex pseudouridine landscape that includes messenger RNA and diverse classes of noncoding RNA in human cells. The known molecular functions of pseudouridine, which include stabilizing RNA conform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5714b8168673a0cddae2f9df51d2c02
https://doi.org/10.1146/annurev-genet-112618-043830
https://doi.org/10.1146/annurev-genet-112618-043830
Autor:
Nicole M, Martinez, Wendy V, Gilbert
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2298
Pseudouridine profiling has revealed many previously unknown sites of the RNA modification pseudouridine (Ψ) in cellular RNAs. All organisms express multiple pseudouridine synthases (PUS) whose RNA targets and mechanisms of targeting remain to be el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cfd8c69e28cae5d05243cdbe71b8164
https://pubmed.ncbi.nlm.nih.gov/34085256
https://pubmed.ncbi.nlm.nih.gov/34085256
Autor:
Thomas M. Carlile, Wendy V. Gilbert, Tristan A Bell, Nicole M. Martinez, Boris Zinshteyn, Amanda Su, Cassandra Schaening
Publikováno v:
Nature chemical biology
Pseudouridine (Ψ) is a post-transcriptional RNA modification that alters RNA-RNA and RNA-protein interactions that affect gene expression. mRNA pseudouridylation was recently discovered as a widespread and conserved phenomenon, but the mechanisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee8f0e4787396a87d5d568889d0b676
https://doi.org/10.1038/s41589-019-0353-z
https://doi.org/10.1038/s41589-019-0353-z
Publikováno v:
Methods in Enzymology ISBN: 9780128235850
Methods Enzymol
Methods Enzymol
Pseudouridine (Ψ) is one of the most abundant modifications in cellular RNAs. High-throughput pseudouridine profiling of eukaryotic mRNAs from cells has revealed novel sites of modification across the transcriptome. Pseudouridine affects RNA structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d6820b4efa0d1bef300565fd32e519
https://doi.org/10.1016/bs.mie.2021.06.026
https://doi.org/10.1016/bs.mie.2021.06.026
Autor:
Nicole M. Martinez, Shashank Sathe, Amanda Su, Cassandra Schaening, Wendy V. Gilbert, Gene W. Yeo, Margaret C. Burns, Julia K. Nussbacher
Eukaryotic messenger RNAs are extensively decorated with modified nucleotides and the resulting epitranscriptome plays important regulatory roles in cells 1. Pseudouridine (Ψ) is a modified nucleotide that is prevalent in human mRNAs and can be dyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98d3dca0d89161b180a0597e4224a7aa
https://doi.org/10.1101/2020.08.29.273565
https://doi.org/10.1101/2020.08.29.273565
Autor:
Nicole M. Martinez, Amanda Su, Margaret C. Burns, Julia K. Nussbacher, Cassandra Schaening, Shashank Sathe, Gene W. Yeo, Wendy V. Gilbert
Publikováno v:
Mol Cell
Pseudouridine is a modified nucleotide that is prevalent in human mRNAs and is dynamically regulated. Here we investigate when in their life cycle mRNAs become pseudouridylated to illuminate the potential regulatory functions of endogenous mRNA pseud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47da9d92d1b0a0f24d694a4b4e5da047
https://doi.org/10.1016/j.molcel.2021.12.023
https://doi.org/10.1016/j.molcel.2021.12.023
Autor:
Kathryn L. Black, Alejandro Barrera, Yoseph Barash, Derek A. Oldridge, Matthew R. Gazzara, Elaine Y. Chung, Shannon L. Maude, Jessica Perazzelli, Simon F. Lacey, Ted J. Hofmann, Elad Jacoby, Colleen T. Harrington, Claudia Lanauze, David M. Barrett, Glendon S. Wu, J. Joseph Melenhorst, John M. Maris, Terry J. Fry, Marco Ruella, Stephan A. Grupp, Elena Sotillo, Saar Gill, Asen Bagashev, Crystal L. Mackall, Kristen W. Lynch, David Allman, Robyn T. Sussman, Nicole M. Martinez, Pichai Raman, Andrei Thomas-Tikhonenko
Publikováno v:
Cancer Discovery. 5:1282-1295
The CD19 antigen, expressed on most B-cell acute lymphoblastic leukemias (B-ALL), can be targeted with chimeric antigen receptor–armed T cells (CART-19), but relapses with epitope loss occur in 10% to 20% of pediatric responders. We detected hemizy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::185a36384ccbe8b2e01c80c5e4daad35
https://doi.org/10.1158/2159-8290.cd-15-1020
https://doi.org/10.1158/2159-8290.cd-15-1020