Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nicole M. Lewandowski"'
Autor:
Nicole M. Lewandowski, Yvette Bordelon, Adam M. Brickman, Sergio Angulo, Usman Khan, Jordan Muraskin, Erica Y. Griffith, Paula Wasserman, Liliana Menalled, Jean Paul Vonsattel, Karen Marder, Scott A. Small, Herman Moreno
Publikováno v:
Neurobiology of Disease, Vol 52, Iss , Pp 84-93 (2013)
Although the huntingtin gene is expressed in brain throughout life, phenotypically Huntington's disease (HD) begins only in midlife and affects specific brain regions. Here, to investigate regional vulnerability in the disease, we used functional mag
Externí odkaz:
https://doaj.org/article/427ce9a5ae5b4fa7ad7e766729e90910
Autor:
Nicole M. Lewandowski, Yvette Bordelon, Adam M. Brickman, Sergio Angulo, Usman Khan, Jordan Muraskin, Erica Y. Griffith, Paula Wasserman, Liliana Menalled, Jean Paul Vonsattel, Karen Marder, Scott A. Small, Herman Moreno
Publikováno v:
Neurobiology of Disease, Vol 54, Iss , Pp 115- (2013)
Externí odkaz:
https://doaj.org/article/00cf0c1babaa476a9669d1ec76e821db
Autor:
Inna Gaisler-Salomon, Sergiy Chornyy, Hanoch Kaphzan, Sharon S Lander, Scott A. Small, Nicole M. Lewandowski, Frank A. Provenzano, Stephen Rayport, Francesca Frigerio, Susana Mingote, Darpan Chakraborty, Pierre Maechler, Usman A. Khan
Publikováno v:
Schizophrenia Bulletin, Vol. 45, No 1 (2019) pp. 127-137
Brain imaging has revealed that the CA1 subregion of the hippocampus is hyperactive in prodromal and diagnosed patients with schizophrenia (SCZ), and that glutamate is a driver of this hyperactivity. Strikingly, mice deficient in the glutamate synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41be438b310ef516412427e8f37d5d17
https://europepmc.org/articles/PMC6293228/
https://europepmc.org/articles/PMC6293228/
Autor:
Paula Wasserman, Liliana B. Menalled, Nicole M. Lewandowski, Jean Paul G. Vonsattel, Jordan Muraskin, Herman Moreno, Usman A. Khan, Scott A. Small, Erica Y. Griffith, Sergio Angulo, Karen Marder, Adam M. Brickman, Yvette Bordelon
Publikováno v:
Neurobiology of Disease, Vol 52, Iss, Pp 84-93 (2013)
Although the huntingtin gene is expressed in brain throughout life, phenotypically Huntington's disease (HD) begins only in midlife to affect specific brain regions. Here, to investigate regional vulnerability in the disease, we used functional magne
Autor:
Pierre Maechler, Stephen Rayport, Hanoch Kaphzan, Sharon S Lander, Reut Donner, Susana Mingote, Scott A. Small, Frank A. Provenzano, Nicole M. Lewandowski, Darpan Chakraborti, Inna Gaisler-Salomon
Publikováno v:
Schizophrenia Bulletin. 43:S109-S110
Background: Glutamatergic abnormalities are commonly observed in schizophrenia (SZ), but all current medications for SZ symptoms target monoaminergic neurotransmitter systems, and are inefficient in treating all symptom clusters. Animal models that c
Autor:
Madeleine A. Johnson, David A. Talmage, Ruei-Che Liu, Ying-Jiun J. Chen, Holly Moore, Gorazd Rosoklija, Lorna W. Role, Andrew J. Dwork, Michael D. Lieberman, Scott A. Schobel, Jay A. Gingrich, Nicole M. Lewandowski, Rose E. Goodchild, Scott A. Small
Publikováno v:
Journal of Neuroscience. 28:6872-6883
Neuregulin-1 (Nrg1)/erbB signaling regulates neuronal development, migration, myelination, and synaptic maintenance. The Nrg1 gene is a schizophrenia susceptibility gene. To understand the contribution of Nrg1 signaling to adult brain structure and b
Autor:
Melissa Geddie, Dagmar Ringe, Anthony Adame, Eliezer Masliah, Barbara Ross, Edward Rockenstein, Karen Marder, Gregory A. Petsko, Scott A. Small, Jean Paul G. Vonsattel, Lucien J. Cote, Lorraine N. Clark, Miguel Verbitsky, Susan Lindquist, Alim Muhammad, Nicole M. Lewandowski, Shulin Ju
The full complement of molecular pathways contributing to the pathogenesis of Parkinson disease (PD) remains unknown. Here we address this issue by taking a broad approach, beginning by using functional MRI to identify brainstem regions differentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf35a73d795496a9e827a6cc6eeff400
https://europepmc.org/articles/PMC2947879/
https://europepmc.org/articles/PMC2947879/
Autor:
Holly Moore, Nao Chuhma, Ottavio Arancio, Inna Gaisler-Salomon, Scott A. Small, Peter D. Balsam, Agnès Conjard-Duplany, René Hen, Yvonne Wang, Stephen Fairhurst, Stephen Rayport, Justine Masson, Farhad Ghoddoussi, Sooyeon Lee, Nicole M. Lewandowski, Hong Zhang, Gretchen M. Miller, Matthew P. Galloway
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 34(10)
Dysregulated glutamatergic neurotransmission has been strongly implicated in the pathophysiology of schizophrenia (SCZ). Recently, presynaptic modulation of glutamate transmission has been shown to have therapeutic promise. We asked whether genetic k
Autor:
Scott A. Small, Nicole M. Lewandowski
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 25(45)
Editor's Note: Toolboxes are a new, occasional feature in the Journal designed to briefly highlight a new method or a resource of general use in neuroscience or to critically analyze existing approaches or methods. For more information, see . When
Autor:
Erica Y. Griffith, Usman A. Khan, Paula Wasserman, Liliana B. Menalled, Herman Moreno, Sergio Angulo, Karen Marder, Jean Paul G. Vonsattel, Jordan Muraskin, Scott A. Small, Adam M. Brickman, Yvette Bordelon, Nicole M. Lewandowski
Publikováno v:
Neurobiology of Disease, Vol 54, Iss, Pp 115-(2013)
a Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA b Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY