Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicole M. Easton"'
Autor:
Joshua A Hayden, Meghan C Hamilton, Lia Grandinetti, Nicole M. Easton, Oliver P Kuehm, Stephen L. Bearne, Colin D. Douglas, Martin St. Maurice
Publikováno v:
Biochemistry. 60:2508-2518
o-Carbonyl arylboronic acids such as 2-formylphenylboronic acid (2-FPBA) are employed in biocompatible conjugation reactions with the resulting iminoboronate adduct stabilized by an intramolecular N-B interaction. However, few studies have utilized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54db55fadbdbb2fe56ba50d6da18bac2
https://doi.org/10.1021/acs.biochem.1c00374
https://doi.org/10.1021/acs.biochem.1c00374
Publikováno v:
Bioorganic Chemistry. 77:640-650
Rational approaches for the design of enzyme inhibitors furnish powerful strategies for developing pharmaceutical agents and tools for probing biological mechanisms. A new strategy for the development of gem-disubstituted substrate-product analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa57f203a78f59309c0c611fa79d83f7
https://doi.org/10.1016/j.bioorg.2018.01.041
https://doi.org/10.1016/j.bioorg.2018.01.041
Publikováno v:
Analytical Biochemistry. 544:80-86
l -Talarate/galactarate dehydratase (TGD) is a member of the enolase superfamily of enzymes and catalyzes the dehydration of either meso-galactarate or l -talarate to form 5-keto-4-deoxy- d -glucarate (5-KDG). To facilitate study of this enzyme and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b9844e7c3487b91595700ee8378b78
https://doi.org/10.1016/j.ab.2017.12.015
https://doi.org/10.1016/j.ab.2017.12.015