Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicole M. Bzdyl"'
Autor:
Jua Iwasaki, Nicole M. Bzdyl, Dion J. M. Lin-Sullivan, Nicolas J. Scheuplein, Maria Emilia Dueñas, Emma de Jong, Nicholas J. Harmer, Ulrike Holzgrabe, Mitali Sarkar-Tyson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionMelioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a disease endemic in many tropical countries globally. Clinical presentation is highly variable, ranging from asymptomatic to fatal septicemia, and thus the
Externí odkaz:
https://doaj.org/article/e8e077d2c0774c93914ba6f7cdb209f7
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1945-1965 (2022)
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by either inhalation or inoculation can lead to severe disease. B. pseudom
Externí odkaz:
https://doaj.org/article/588b2f5f67dc4e0e85eabe9fb00ac071
Autor:
Jua Iwasaki, Donald D. Lorimer, Mirella Vivoli-Vega, Emily A. Kibble, Christopher S. Peacock, Jan Abendroth, Stephen J. Mayclin, David M. Dranow, Phillip G. Pierce, David Fox, Maria Lewis, Nicole M. Bzdyl, Sofie S. Kristensen, Timothy J. J. Inglis, Charlene M. Kahler, Charles S. Bond, Anja Hasenkopf, Florian Seufert, Jens Schmitz, Laura E. Marshall, Andrew E. Scott, Isobel H. Norville, Peter J. Myler, Ulrike Holzgrabe, Nicholas J. Harmer, Mitali Sarkar-Tyson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1625-1634
Background The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in a wide range of pathogenic m
Autor:
Mitali Sarkar-Tyson, Nicolas J Scheuplein, Nicole M. Bzdyl, Ulrike Holzgrabe, Theresa Lohr, Emily A Kibble
Publikováno v:
Journal of Medicinal Chemistry. 63:13355-13388
Infectious diseases are a major cause of morbidity and mortality worldwide, exacerbated by increasing antibiotic resistance in many bacterial species. The development of drugs with new modes of action is essential. A leading strategy is antivirulence
Autor:
Elizabeth Geelhoed, Graham Weaire-Buchanan, Nicole M. Bzdyl, Michael J. Leung, Ben Payne, Timothy J. J. Inglis, Nadezda Urosevic, Michael McIntyre, Ray Brockenshire
Publikováno v:
Journal of Medical Microbiology. 67:669-675
Purpose. In this field trial of rapid blood culture identification (BCID), we aimed to determine whether the improved speed and accuracy of specific BCID predicted in our earlier pilot study could be obtained in regional hospitals by deploying a mult
Autor:
Nicole M. Bzdyl, Geoffrey W. Coombs, Andrew E. Scott, Timothy J. J. Inglis, Nichollas E. Scott, Timothy P. Atkins, Mitali Sarkar-Tyson, Derek S. Sarovich, Isobel H. Norville, Charlene M. Kahler, Stanley Pang
Publikováno v:
Infection and Immunity. 87
Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic to Southeast Asia and northern Australia. Mortality rates in these areas are high even with antimicrobial treatment, and there are few options for effective therapy. T
Autor:
Nicole M, Bzdyl, Nichollas E, Scott, Isobel H, Norville, Andrew E, Scott, Timothy, Atkins, Stanley, Pang, Derek S, Sarovich, Geoffrey, Coombs, Timothy J J, Inglis, Charlene M, Kahler, Mitali, Sarkar-Tyson
Publikováno v:
Infection and immunity. 87(10)
Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic to Southeast Asia and northern Australia. Mortality rates in these areas are high even with antimicrobial treatment, and there are few options for effective therapy. T
Autor:
Charlene M. Kahler, Jutta Ebert, Vera Kozjak-Pavlovic, Anastasija Reimer, Mitali Sarkar-Tyson, Nicole M. Bzdyl, Ulrike Holzgrabe, Matthias Weiwad, Florian Seufert, Thomas Rudel
Publikováno v:
International Journal of Antimicrobial Agents. 48:401-408
The pathogenic bacteria Chlamydia trachomatis, Neisseria gonorrhoeae and Neisseria meningitidis express the surface-exposed macrophage infectivity potentiator (MIP)-like protein, which plays a role in their pathogenicity. MIP exhibits a peptidyl-prol
Autor:
Timothy J. J. Inglis, Nadezda Urosevic, Elizabeth Geelhoed, I-Ly Joanna Chua, Nicole M. Bzdyl, Michael J. Leung
Publikováno v:
Journal of Medical Microbiology. 65:56-61
Rapid identification of bacteria isolated from blood cultures by direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is now in wide spread use in major centres but is not yet feasible in smaller hospital
Publikováno v:
New Microbes and New Infections, Vol 8, Iss C, Pp 171-173 (2015)
New Microbes and New Infections
New Microbes and New Infections
The facultative anaerobic Gram-negative species Escherichia albertii has been isolated from human faeces in gastrointestinal infection and from a range of wild bird species. Here we report the first case of a febrile infection associated with E. albe