Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Nicole M. Aiello"'
Autor:
Toni Celià-Terrassa, Caleb Bastian, Daniel D. Liu, Brian Ell, Nicole M. Aiello, Yong Wei, Jose Zamalloa, Andres M. Blanco, Xiang Hang, Dmitriy Kunisky, Wenyang Li, Elizabeth D. Williams, Herschel Rabitz, Yibin Kang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The epithelial-mesenchymal transition (EMT) is a dynamic process that plays important roles in cancer progression and metastasis. Here, the authors characterize a non-linear hysteretic response of E-cadherin repression during TGFβ-induced EMT that i
Externí odkaz:
https://doaj.org/article/15369d2c47794345b6112dc4b6b051de
Autor:
Nicole M. Aiello, David L. Bajor, Robert J. Norgard, Amine Sahmoud, Neha Bhagwat, Minh N. Pham, Toby C. Cornish, Christine A. Iacobuzio-Donahue, Robert H. Vonderheide, Ben Z. Stanger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Metastatic colonization—the growth of single metastatic cells or small lesions into gross metastases—is poorly understood. Here, the authors characterize the natural history of metastatic growth and assess the impact of chemotherapy in an autocht
Externí odkaz:
https://doaj.org/article/bf2c2323822742288d632d0fd9cd990d
Autor:
Nicole M. Aiello, Ben Z. Stanger
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 2, Pp 105-114 (2016)
The hallmark of embryonic development is regulation – the tendency for cells to find their way into organized and ‘well behaved’ structures – whereas cancer is characterized by dysregulation and disorder. At face value, cancer biology and dev
Externí odkaz:
https://doaj.org/article/6152afc8272548d587975bfb6660ff55
Autor:
Toni Celià-Terrassa, Caleb Bastian, Daniel D. Liu, Brian Ell, Nicole M. Aiello, Yong Wei, Jose Zamalloa, Andres M. Blanco, Xiang Hang, Dmitriy Kunisky, Wenyang Li, Elizabeth D. Williams, Herschel Rabitz, Yibin Kang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the spelling of the author Daniel D. Liu, which was incorrectly given as Daniel Liu. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/f23791fa2eb7461e99644e2df11c7e5a
Autor:
Corbett T. Berry, Xiaodong Feng, Bruce D. Freedman, Jared B Bassett, Mohit Kumar Jolly, Taiji Yamazoe, Maximilian D. Wengyn, Robert J. Norgard, David Lyden, Priyanka Chakraborty, Anil K. Rustgi, David Balli, Michele Cioffi, Riley Payne, Nicole M Aiello-Couzo, Jason R. Pitarresi, Il Kyu Kim, Jinyang Li, Ben Z. Stanger, Ian W. Folkert, Derick N Rosario-Berrios, Ian D. Millstein, J. Kevin Foskett, Kathryn Sun, J. Silvio Gutkind, Ravikanth Maddipati
Publikováno v:
EMBO Rep
Epithelial plasticity, or epithelial-to-mesenchymal transition (EMT), is a well-recognized form of cellular plasticity, which endows tumor cells with invasive properties and alters their sensitivity to various agents, thus representing a major challe
Autor:
Yibin Kang, Nicole M. Aiello
Publikováno v:
The Journal of Experimental Medicine
In this review, Aiello and Kang discuss the molecular mechanisms, regulatory networks, and functional consequences of epithelial–mesenchymal transition (EMT) in the context of cancer metastasis, with a particular focus on partial EMT and cellular p
Autor:
Nicole M, Aiello-Couzo, Yibin, Kang
Publikováno v:
Nature cell biology. 22(8)
Autor:
Toby C. Cornish, Minh Pham, Robert H. Vonderheide, Ben Z. Stanger, Christine A. Iacobuzio-Donahue, Nicole M. Aiello, Neha Bhagwat, Amine Sahmoud, Robert J. Norgard, David L. Bajor
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications
Nature Communications
Most cancer-associated deaths result from metastasis. However, it remains unknown whether the size, microenvironment or other features of a metastatic lesion dictate its behaviour or determine the efficacy of chemotherapy in the adjuvant (micrometast
Autor:
Anil K. Rustgi, Robert J. Norgard, Jinyang Li, Yogev Sela, Ben Z. Stanger, David Balli, Ravikanth Maddipati, Allyson J. Merrell, Jason R. Pitarresi, Kathryn Sun, Taiji Yamazoe, Maximilian D. Wengyn, Salina Yuan, Derick N Rosario-Berrios, Nicole M. Aiello
Publikováno v:
Cancer Research. 79:B38-B38
Metastasis and chemoresistance—the two main reasons for the high mortality of cancer—are associated with a form of cellular plasticity known as epithelial-to-mesenchymal transition (EMT). Cancer cells undergoing EMT become invasive, facilitating
Autor:
David Balli, Robert J. Norgard, Salina Yuan, Ravikanth Maddipati, Nicole M. Aiello, Amine Sahmoud, Jinyang Li, Ben Z. Stanger, Emma E. Furth, Dafna Bar-Sagi, Taylor A. Black, Taiji Yamazoe
Summary Epithelial-mesenchymal transition (EMT) is strongly implicated in tumor cell invasion and metastasis. EMT is thought to be regulated primarily at the transcriptional level through the repressive activity of EMT transcription factors. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88d5a3587a5a46f80ee4d8d5cc8b02c
https://europepmc.org/articles/PMC6014628/
https://europepmc.org/articles/PMC6014628/