Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nicole M Templeman"'
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153280 (2016)
Insulin is an essential hormone with key roles in energy homeostasis and body composition. Mice and rats, unlike other mammals, have two insulin genes: the rodent-specific Ins1 gene and the ancestral Ins2 gene. The relationships between insulin gene
Externí odkaz:
https://doaj.org/article/dbc9864afe50435292a53ee1f5b61551
Autor:
James D. Johnson, Obelia Haida, Peter Overby, Gareth E. Lim, José Rodrigo Pauli, Nicole M. Templeman, Wang S, José Diego Botezelli, Lorenzo Lindo
Hyperinsulinemia plays a causal role in adiposity tissue expansion. We have previously shown that mice with reduced insulin gene dosage have increased energy expenditure, but the tissue-specific molecular mechanisms involved in the effects of abrogat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49325048c16f4f95d9be01b1b7954c50
https://doi.org/10.1101/2020.03.31.018432
https://doi.org/10.1101/2020.03.31.018432
Evolutionarily conserved signaling pathways are crucial for adjusting growth, reproduction, and cell maintenance in response to altered environmental conditions or energy balance. However, we have an incomplete understanding of the signaling networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06360a064e8f61fdbde21e3463ff461
Autor:
Faria Athar, Nicole M. Templeman
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 266:111152
Female reproductive health has been historically understudied and underfunded. Here, we present the advantages of using a free-living nematode, Caenorhabditis elegans, as an animal system to study fundamental aspects of female reproductive health. C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b49a400a15cc81b5404a97c728afe3
https://doi.org/10.1016/j.cbpa.2022.111152
https://doi.org/10.1016/j.cbpa.2022.111152
Autor:
Nicole M. Templeman, Coleen T. Murphy
Publikováno v:
The Journal of Cell Biology
Templeman and Murphy review how key nutrient-sensing signaling pathways—the insulin/IGF-1, mTOR, and AMPK pathways—regulate and coordinate reproductive and somatic aging.
Nutrients are necessary for life, as they are a crucial requirement fo
Nutrients are necessary for life, as they are a crucial requirement fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b4a158abee5284b8720e25392ca2c9
http://europepmc.org/articles/PMC5748989
http://europepmc.org/articles/PMC5748989
Autor:
Alexander G. Little, Matthew E. Pamenter, Michael S. Hedrick, Christopher D. Moyes, Divya Sitaraman, Nicole M. Templeman, William G. Willmore
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 259:110987
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0003f83a2452a2110be20c234983b9
https://doi.org/10.1016/j.cbpa.2021.110987
https://doi.org/10.1016/j.cbpa.2021.110987
Autor:
Alexander G. Little, Michael S. Hedrick, Nicole M. Templeman, Matthew E. Pamenter, William G. Willmore, Christopher D. Moyes, Divya Sitaraman
Publikováno v:
Comp Biochem Physiol B Biochem Mol Biol
This review serves as an introduction to a Special Issue of Comparative Biochemistry and Physiology, focused on using non-human models to study biomedical physiology. The concept of a model differs across disciplines. For example, several models are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0518025b5495bd3855aca8201c9ed4cd
https://doi.org/10.1016/j.cbpb.2021.110593
https://doi.org/10.1016/j.cbpb.2021.110593
Autor:
Sunita Sinha, Leonard J. Foster, Stephane Flibotte, James D. Johnson, Gareth E. Lim, Corey Nislow, Nicole M. Templeman, Jenny H. L. Chik
Publikováno v:
Cell Reports, Vol 20, Iss 2, Pp 451-463 (2017)
Summary The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. Genetic downregulation of insulin/insulin-like growth factor 1 (Igf1) signaling components can extend invertebrate and mammalian life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b5e471060814dab5edf308c55e72f8
https://doi.org/10.1016/j.celrep.2017.06.048
https://doi.org/10.1016/j.celrep.2017.06.048
Autor:
William G. Willmore, Michael S. Hedrick, Matthew E. Pamenter, Nicole M. Templeman, Christopher D. Moyes, Alexander G. Little, Divya Sitaraman
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 256:110938
The Publisher regrets that this article is an accidental duplication of an article that has already been published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, Volume 255, 2021, 110593, https://doi.org/10.101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca0b0884bb0b2aef321cb3b7e05bdab
https://doi.org/10.1016/j.cbpa.2021.110938
https://doi.org/10.1016/j.cbpa.2021.110938
Publikováno v:
Dev Cell
Evolutionarily conserved signaling pathways are crucial for adjusting growth, reproduction, and cell maintenance in response to altered environmental conditions or energy balance. However, we have an incomplete understanding of the signaling networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819465348e02cfbeaded1438ba334ac1
https://doi.org/10.1016/j.devcel.2020.05.023
https://doi.org/10.1016/j.devcel.2020.05.023