Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nicole M Brossier"'
Autor:
Shannon M. Weber, Nicole M. Brossier, Amanda Prechtl, Stephen Barnes, Landon S. Wilson, Stephanie N. Brosius, Jody Fromm Longo, Steven L. Carroll
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-21 (2021)
Abstract Background Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1). Neurofibromin loss potentially hyperactivates classic Ras (H-Ras, N-Ras, K-Ras), M
Externí odkaz:
https://doaj.org/article/b179198ca90645669df1b83a5b802b53
Publikováno v:
Child's Nervous System. 38:2245-2249
Background Low-grade gliomas (LGGs) occurring in children can result in many different neurologic complications, including seizures. MEK inhibitors are increasingly being used to treat LGG, but their effect on associated neurologic symptoms has not b
Publikováno v:
Pediatric Blood & Cancer. 70
Autor:
Stephanie N. Brosius, Landon Wilson, Nicole M. Brossier, Steven L. Carroll, Jody Fromm Longo, Shannon M. Weber, Stephen Barnes, Amanda Prechtl
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-21 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1). Neurofibromin loss potentially hyperactivates classic Ras (H-Ras, N-Ras, K-Ras), M-Ras, and
Publikováno v:
Neuro-oncology Advances
Autor:
Evan Cantor, Ashley Meyer, Andrea Ogle, Michele McHugh, Mary Beck, Tammy Green, Lakshmi Ramachandran, Sonika Dahiya, Andrew Cluster, Nicole M Brossier, Mohamed S Abdelbaki, David Limbrick, Stephanie Perkins, Margaret Shatara
Publikováno v:
Neuro-Oncology. 24:i118-i119
INTRODUCTION: Medulloblastoma is the most common malignant brain tumor in children, with 5-year overall survival (OS) ranging from 60%-95% depending on subgroup and risk status. The POG 8631/CCG 923 trial (accrual 1986-1990) found a 63% 5 year OS for
Autor:
Evan Cantor, Ashley Meyer, Andrea Ogle, Margaret Shatara, Andrew Cluster, Mohamed S Abdelbaki, Stephanie Morris, Judith Weisenberg, Nicole M Brossier
Publikováno v:
Neuro-Oncology. 24:i96-i97
BACKGROUND: Low-grade gliomas (LGG) are the most common solid tumor of childhood and can result in neurologic complications, including seizures, focal neurologic deficits, and learning difficulties. Molecularly targeted agents are increasingly being
Autor:
Evan Cantor, Andrea Ogle, Ashley Meyer, Margaret Shatara, Nicole M Brossier, Mohamed S Abdelbaki, Jennifer Strahle, Andrew Cluster
Publikováno v:
Neuro-Oncology. 24:i97-i97
INTRODUCTION: Ganglioglioma is a low grade neoplasm consisting of dysplastic neuronal and neoplastic glial cells and accounts for 5% of pediatric CNS tumors. Management often includes CNS diversion. There have been case reports in which platinum cont
Autor:
Evan Cantor, Margaret Shatara, Ashley Meyers, Andrea Ogle, Michele McHugh, Stephanie Reiners, Andrew Cluster, Mohamed S Abdelbaki, Pournima Navalkele, Nicole M Brossier
Publikováno v:
Neuro-Oncology. 24:i87-i87
BACKGROUND: MEK inhibitor therapy is increasingly being utilized for the treatment of pediatric tumors, including low-grade glioma, plexiform neurofibroma and Langerhans cell histiocytosis. These drugs are well-tolerated but do have risk of toxicity,
Autor:
Evan Cantor, Anne Cochrane, Andrea Ogle, Ashley Meyer, Nicole M Brossier, Margaret Shatara, Andrew Cluster, Mohamed S Abdelbaki
Publikováno v:
Neuro-Oncology. 24:i57-i57
BACKGROUND: CNS Germinomas are highly radio-sensitive tumors with an excellent survival rate of more than 90%. The current standard of care combines chemotherapy with reduced-dose radiotherapy to minimize the adverse effects and long-term effects ass