Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Nicole M, Fletcher"'
Autor:
Ghassan M. Saed, Nicole M. Fletcher, Harvey Sharma, Axel Stenmark Tullberg, Ella Ittner, Toshima Z. Parris, Daniella Pettersson, Anikó Kovács, Elisabeth Werner Rönnerman, Pernilla Dahm-Kähler, Anna Portela, Pamela D. Garzone, Robert Morris, Khalil Helou
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200864- (2024)
Lemur tail kinase 3 (LMTK3) belongs to a family of tyrosine kinases that are known to correlate with tumor grade and patient survival in some cancers. Here, we validated LMTK3 as a specific target and a prognostic biomarker in ovarian cancer (OC). In
Externí odkaz:
https://doaj.org/article/c738a39ca4d94f82901e0ffdd34b58cd
Autor:
Hala LUTFI, Thea K. KIRSCH-MANGU, Nicole M. FLETCHER-KING, Douglas M. RUDEN, Michael P. DIAMOND, Ghassan M. SAED
Publikováno v:
Minerva obstetrics and gynecology.
The link between post-operative adhesion development and epigenetic modifications is important in understanding the mechanism behind their formation. The purpose of this study was to determine whether epigenetic differences exist between primary fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6289217bdfe3ccd3eb650150b1bb7e30
https://pubmed.ncbi.nlm.nih.gov/36222785
https://pubmed.ncbi.nlm.nih.gov/36222785
Publikováno v:
Minerva Obstetrics and Gynecology.
2,4-dinitrophenol (DNP), an uncoupling mitochondrial agent, has been identified as a source of oxidative stress and linked to the pathogenesis of ovarian cancer. In this study, we determine the cytotoxic effect of DNP alone or in combination with che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b557b961014b884ff3e9afda8c76d0b
https://doi.org/10.23736/s2724-606x.22.05204-6
https://doi.org/10.23736/s2724-606x.22.05204-6
Autor:
Coral L. Murrant, Nicole M. Fletcher
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(5)
Historically, capillaries have been viewed as the microvascular site for flux of nutrients to cells and removal of waste products. Capillaries are the most numerous blood vessel segment within the tissue, whose vascular wall consists of only a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d57d6526796943407d92b64f1b8de0a
https://pubmed.ncbi.nlm.nih.gov/36149771
https://pubmed.ncbi.nlm.nih.gov/36149771
Publikováno v:
European Journal of Applied Physiology. 121:1241-1254
We explore the motor unit recruitment and control of perfusion of microvascular units in skeletal muscle to determine whether they coordinate to match blood flow to metabolic demand. The PubMed database was searched for historical, current and releva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1f89d3e9ba99cd85374758e9451e03
https://doi.org/10.1007/s00421-021-04598-4
https://doi.org/10.1007/s00421-021-04598-4
Publikováno v:
Gynecological Endocrinology. 37:349-352
To test whether recombinant anti-Müllerian hormone (rAMH) could exert an inhibitory function on BRCA1/2 expression in human ovarian cortex.Pilot study on ovariectomized nude mice xenotransplanted with human vitrified/warmed ovarian cortex and treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d53cbb9fa44958ca88b861749b8fec
https://doi.org/10.1080/09513590.2020.1828328
https://doi.org/10.1080/09513590.2020.1828328
Publikováno v:
Reproductive Sciences. 26:1603-1612
Genital use of talcum powder and its associated risk of ovarian cancer is an important controversial topic. Epithelial ovarian cancer (EOC) cells are known to manifest a persistent prooxidant state. Here we demonstrated that talc induces significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5fc3f8d7e26bbb7be48f322d946bf3
https://doi.org/10.1177/1933719119831773
https://doi.org/10.1177/1933719119831773
Autor:
Rong Fan, Ghassan M. Saed, Amy K Harper, Xin Wang, Robert T. Morris, Thea K Mangu, Nicole M. Fletcher
Publikováno v:
Minerva obstetrics and gynecology.
BACKGROUND Several studies have linked perineal use of talcum powder to increased risk of ovarian cancer (OC). Here, we determined that exposure to talcum powder induces malignant transformation in human normal ovarian cells. METHODS Human primary ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f25bb8d4cfddd53f4738bda5c561f81
https://pubmed.ncbi.nlm.nih.gov/34825792
https://pubmed.ncbi.nlm.nih.gov/34825792
Autor:
Jimmy Belotte, Nicole M Fletcher, Mohammed G Saed, Mohammed S Abusamaan, Gregory Dyson, Michael P Diamond, Ghassan M Saed
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135739 (2015)
Ovarian cancer is the deadliest of all gynecologic cancers. Recent evidence demonstrates an association between enzymatic activity altering single nucleotide polymorphisms (SNP) with human cancer susceptibility. We sought to evaluate the association
Externí odkaz:
https://doaj.org/article/687ad7d9c17d4fe9a82117309b840c88
Publikováno v:
European journal of applied physiology. 121(5)
We explore the motor unit recruitment and control of perfusion of microvascular units in skeletal muscle to determine whether they coordinate to match blood flow to metabolic demand.The PubMed database was searched for historical, current and relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60212b766f8c8db8b36fd02a3144460b
https://pubmed.ncbi.nlm.nih.gov/33538852
https://pubmed.ncbi.nlm.nih.gov/33538852