Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nicole M, Duffy"'
Autor:
Sean A. Halpin, Nicole M. Duffy
Publikováno v:
Journal of Affective Disorders Reports, Vol 1, Iss , Pp 100017- (2020)
Background: Most studies of non-suicidal self-injury (NSSI) investigate individuals who are currently self-injuring. The current study aimed to identify factors associated with continuation or cessation of NSSI from adolescence to adulthood. Method:
Externí odkaz:
https://doaj.org/article/664dd6f01909461eae0b6451711ab92d
Autor:
Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Jean-François Truchon, Alexander L. Perryman, Victor Pau, Igor Kurinov, Karl E. Zahn, Marie-Eve Leclaire, Robert Papp, Marie-Claude Mathieu, Martine Hamel, Nicole M. Duffy, Claude Godbout, Matias Casas-Selves, Jean-Pierre Falgueyret, Prasamit S. Baruah, Olivier Nicolas, Rino Stocco, Hugo Poirier, Giovanni Martino, Alexanne Bonneau Fortin, Anne Roulston, Amandine Chefson, Stéphane Dorich, Miguel St-Onge, Purvish Patel, Charles Pellerin, Stéphane Ciblat, Thomas Pinter, Francis Barabé, Majida El Bakkouri, Paranjay Parikh, Christian Gervais, Agnel Sfeir, Yael Mamane, Stephen J. Morris, W. Cameron Black, Frank Sicheri, Michel Gallant
Publikováno v:
Journal of Medicinal Chemistry. 65:13198-13215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947c93bf7b6803db8ed4beb935e92af5
https://doi.org/10.1021/acs.jmedchem.2c00998
https://doi.org/10.1021/acs.jmedchem.2c00998
Autor:
David Gallo, Jordan T. F. Young, Jimmy Fourtounis, Giovanni Martino, Alejandro Álvarez-Quilón, Cynthia Bernier, Nicole M. Duffy, Robert Papp, Anne Roulston, Rino Stocco, Janek Szychowski, Artur Veloso, Hunain Alam, Prasamit S. Baruah, Alexanne Bonneau Fortin, Julian Bowlan, Natasha Chaudhary, Jessica Desjardins, Evelyne Dietrich, Sara Fournier, Chloe Fugère-Desjardins, Theo Goullet de Rugy, Marie-Eve Leclaire, Bingcan Liu, Vivek Bhaskaran, Yael Mamane, Henrique Melo, Olivier Nicolas, Akul Singhania, Rachel K. Szilard, Ján Tkáč, Shou Yun Yin, Stephen J. Morris, Michael Zinda, C. Gary Marshall, Daniel Durocher
Publikováno v:
Nature. 604:749-756
Amplification of the CCNE1 locus on chromosome 19q12 is prevalent in multiple tumour types, particularly in high-grade serous ovarian cancer, uterine tumours and gastro-oesophageal cancers, where high cyclin E levels are associated with genome instab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc789be54b458503be76fad03b732048
https://doi.org/10.1038/s41586-022-04638-9
https://doi.org/10.1038/s41586-022-04638-9
Autor:
Monica, Bubenik, Pavel, Mader, Philippe, Mochirian, Fréderic, Vallée, Jillian, Clark, Jean-François, Truchon, Alexander L, Perryman, Victor, Pau, Igor, Kurinov, Karl E, Zahn, Marie-Eve, Leclaire, Robert, Papp, Marie-Claude, Mathieu, Martine, Hamel, Nicole M, Duffy, Claude, Godbout, Matias, Casas-Selves, Jean-Pierre, Falgueyret, Prasamit S, Baruah, Olivier, Nicolas, Rino, Stocco, Hugo, Poirier, Giovanni, Martino, Alexanne Bonneau, Fortin, Anne, Roulston, Amandine, Chefson, Stéphane, Dorich, Miguel, St-Onge, Purvish, Patel, Charles, Pellerin, Stéphane, Ciblat, Thomas, Pinter, Francis, Barabé, Majida, El Bakkouri, Paranjay, Parikh, Christian, Gervais, Agnel, Sfeir, Yael, Mamane, Stephen J, Morris, W Cameron, Black, Frank, Sicheri, Michel, Gallant
Publikováno v:
Journal of medicinal chemistry. 65(19)
DNA polymerase theta (Polθ) is an attractive synthetic lethal target for drug discovery, predicted to be efficacious against breast and ovarian cancers harboring BRCA-mutant alleles. Here, we describe our hit-to-lead efforts in search of a selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::531f44b082fb5f00fe6c2f82d97a48bc
https://pubmed.ncbi.nlm.nih.gov/36126059
https://pubmed.ncbi.nlm.nih.gov/36126059
Publikováno v:
Psycho-Oncology. 30:421-425
The Institute of Medicine (IOM) report Cancer Care for the Whole Patient: Meeting Psychosocial Needs outlines a standard of care that includes the provision of psychosocial care across the cancer care continuum. 1 Additionally, evidence supports the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9372eb0a9a58adbb2daecff2f06dc29b
https://doi.org/10.1002/pon.5626
https://doi.org/10.1002/pon.5626
Autor:
Hao Huang, Beihua Dong, Frank Sicheri, Yize Li, Robert H. Silverman, Jinle Tang, Christina Gaughan, Daniel Mao, Shuvojit Banerjee, Nicolas Tavernier, Gerald D. Gish, Manisha Talukdar, Salima Daou, Susan R. Weiss, Babal K. Jha, Abiodun A. Ogunjimi, Nicole M. Duffy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The OAS–RNase L system is an innate immunity pathway activated by viral infection. Viral dsRNA stimulates OAS enzymes to produce short 2′,5′-oligoadenylates (2-5A) that activate RNase L, resulting in cleavage of single-stranded (ss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6862d04f43e5ff97c3a16c0c547a9afe
https://doi.org/10.1073/pnas.2006883117
https://doi.org/10.1073/pnas.2006883117
Publikováno v:
Psycho-Oncology. 26:1444-1454
Background There is increasing recognition of the unique physical and psychosocial concerns of the growing population of cancer survivors. An emerging literature demonstrates that fear of cancer recurrence (FCR) is a problematic long-term and late ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daf6cfbde53e37c1a45ad16a92469dcd
https://doi.org/10.1002/pon.4168
https://doi.org/10.1002/pon.4168
Publikováno v:
Journal of Comparative Physiology B. 181:219-238
In water of varying ion content, the gills and kidney of fishes contribute significantly to the maintenance of salt and water balance. However, little is known about the molecular architecture of the tight junction (TJ) complex and the regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986fb3b3d1273d2b23119f89fdcd0875
https://doi.org/10.1007/s00360-010-0517-3
https://doi.org/10.1007/s00360-010-0517-3
Publikováno v:
Psycho-oncology. 26(10)
There is increasing recognition of the unique physical and psychosocial concerns of the growing population of cancer survivors. An emerging literature demonstrates that fear of cancer recurrence (FCR) is a problematic long-term and late effect for ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d27e91348f0bd04d8af7ec2fb612834
https://pubmed.ncbi.nlm.nih.gov/27246348
https://pubmed.ncbi.nlm.nih.gov/27246348
Autor:
Michael Prakesch, Rima Al-awar, Kenneth Lee, Lynn Lehmann, Gennadiy Poda, Danka Vuga, David Chiovitti, Colleen Schweitzer, Marella D. Canny, Julie L. Lucas, John B. Patterson, Nero Thevakumaran, Andras Toro, Nicole M. Duffy, Qingping Zeng, Igor Kurinov, Daniel Durocher, David Uehling, Victor Tam, Brian J. Wilson, Manisha Talukdar, Mario Sanches, Frank Sicheri
Publikováno v:
Nature communications
Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA substrates to re-establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a763c3a28c964003e2743b791e1302b
https://pubmed.ncbi.nlm.nih.gov/25164867
https://pubmed.ncbi.nlm.nih.gov/25164867